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Results for “BRCA Mutations”

186 trials

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Showing 20 of 186 results

Testing effectiveness (Phase 2)UnknownNCT04692740
What this trial is testing

Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial)

Who this might be right for
Pancreatic Ductal Adenocarcinoma
Michele Reni 20
Testing effectiveness (Phase 2)UnknownNCT02681562
What this trial is testing

Olaparib in Locally Advanced ER, PgR and HER2 Negative (Triple Negative) and in Locally Advanced Germline BRCA Mutation-positive Breast Cancer Patients

Who this might be right for
Breast CancerTriple Negative Breast Cancer
Istituti Ospitalieri di Cremona 45
Not applicableStudy completedNCT03471572
What this trial is testing

Study to Assess Prevalence of BRCA1 and BRCA2 Mutation Among Ovarian, Primary Peritoneal and Fallopian Tube Cancer Patients in India

Who this might be right for
Ovarian Cancer
AstraZeneca 240
Not applicableLooking for participantsNCT06588322
What this trial is testing

Detection of Homologous Recombination Pathway Gene Mutations in Circulating Tumour DNA From BRCA-mutated Ovarian Cancer Patients Receiving First-line PARP Inhibitor Maintenance Therapy

Who this might be right for
Ovarian Cancer
Institut Claudius Regaud 130
Not applicableLooking for participantsNCT07498829
What this trial is testing

Population Based Germline Testing for Early Detection and Prevention of Cancer

Who this might be right for
Breast Cancer RiskOvarian Cancer RiskCancer Gene Mutation
Queen Mary University of London 6,000
Not applicableActive Not RecruitingNCT02462460
What this trial is testing

Rapid Pancreatic and Ovarian Screening MR Imaging With Motion Corrected T1, T2, and Advanced Diffusion Weighted Imaging for Patients With BRCA Mutation Who Undergo Screening Breast MRI

Who this might be right for
Screening Breast MRI in Patients Who Are BRCA Mutation Carriers
Memorial Sloan Kettering Cancer Center 63
Large-scale testing (Phase 3)Active Not RecruitingNCT01844986
What this trial is testing

Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy.

Who this might be right for
Newly DiagnosedAdvanced Ovarian CancerFIGO Stage III-IV+4 more
AstraZeneca 450
Not applicableStudy completedNCT01251900
What this trial is testing

BRCA Mutations in Latinas

Who this might be right for
Breast Neoplasms
National Cancer Institute (NCI) 266
Not applicableLooking for participantsNCT00823654
What this trial is testing

Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 609
Early research (Phase 1)Study completedNCT01104259
What this trial is testing

Veliparib, Cisplatin, and Vinorelbine Ditartrate in Treating Patients With Recurrent and/or Metastatic Breast Cancer

Who this might be right for
Estrogen Receptor-negative Breast CancerHER2-negative Breast CancerHereditary Breast/Ovarian Cancer - BRCA1+6 more
University of Washington 50
Early research (Phase 1)Not Yet RecruitingNCT07088588
What this trial is testing

Study of SYN608 for the Treatment of Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid CancerMetastatic Solid TumorOvarian Cancer+3 more
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd 105
Not applicableStudy completedNCT04012229
What this trial is testing

IMpact of Breast cAncer Gene Status on Survival in Adjuvant Breast Cancer (IMBASSA)

Who this might be right for
Breast CancerBRCA1 MutationBRCA2 Mutation
Centre Hospitalier Universitaire de Besancon 2,295
Early research (Phase 1)Not Yet RecruitingNCT06614751
What this trial is testing

A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway

Who this might be right for
Solid CancersBRCA MutationHRD Cancer+8 more
Danatlas Pharmaceuticals Co., Ltd 112
Not applicableNot Yet RecruitingNCT05331209
What this trial is testing

Acupuncture With/Without Self-acupressure for Post-oophorectomy Hot Flashes in BRCA Carriers

Who this might be right for
Hot FlashesMenopause Surgical
Shaare Zedek Medical Center 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT06033092
What this trial is testing

Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion

Who this might be right for
BRCA MutationPALB2 Gene MutationDuctal Carcinoma in Situ+6 more
European Institute of Oncology 200
Early research (Phase 1)Study completedNCT00892736
What this trial is testing

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Who this might be right for
Basal-Like Breast CarcinomaBRCA1 Mutation CarrierBRCA2 Mutation Carrier+14 more
National Cancer Institute (NCI) 98
Large-scale testing (Phase 3)Not Yet RecruitingNCT07628504
What this trial is testing

Sac-TMT Sequential Capecitabine Versus Capecitabine in Early-Stage High-Risk Triple-Negative Breast Cancer Without BRCA Mutations

Who this might be right for
Adjuvant Drug Therapy
Fudan University 420
Not applicableStudy completedNCT03470402
What this trial is testing

Decision Support for BRCA Testing in Ethnically Diverse Women

Who this might be right for
Breast CancerBRCA1 MutationBRCA2 Mutation+1 more
Columbia University 276
Not applicableNot Yet RecruitingNCT06860217
What this trial is testing

Robotic Nipple Sparing Mastectomy with Immediate Reconstruction

Who this might be right for
Breast CancerDCISBRCA Mutation
European Institute of Oncology 24
Not applicableNot Yet RecruitingNCT06393543
What this trial is testing

International Registration of Isolated STIC: to Report and Investigate the Risk of Serous Peritoneal Carcinomatosis

Who this might be right for
BRCA MutationSerous Tubal Intraepithelial CarcinomaOvarian Carcinoma+1 more
Radboud University Medical Center 600
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