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Results for “BRCA-Mutated Breast Carcinoma”

105 trials

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Showing 20 of 105 results

Not applicableLooking for participantsNCT03667417
What this trial is testing

Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation

Who this might be right for
Breast CancersOvarian Cancers
Institut Paoli-Calmettes 5,000
Not applicableStudy completedNCT00956384
What this trial is testing

One-stage Breast Reconstruction Using Dermal Matrix/Implant Versus Two-stage Expander/Implant Procedure

Who this might be right for
Breast Cancer
University Health Network, Toronto 198
Not applicableStudy completedNCT03590938
What this trial is testing

Lynparza Breast Cancer Clinical Experience Investigation

Who this might be right for
Breast Cancer
AstraZeneca 111
Testing effectiveness (Phase 2)Looking for participantsNCT05485766
What this trial is testing

Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer

Who this might be right for
Triple Negative Breast NeoplasmsTriple Negative Breast CancerBreast Neoplasms+5 more
Okayama University 23
Not applicableStudy completedNCT05750719
What this trial is testing

BRCA and NACT in TNBC Patients

Who this might be right for
Triple-Negative Breast Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 136
Not applicableUnknownNCT04368442
What this trial is testing

Cohort Study of Patients With HER2-negative MBC and BRCA 1/2 Pathogenic Mutation

Who this might be right for
Breast Cancer Metastatic
Samsung Medical Center 583
Testing effectiveness (Phase 2)Study completedNCT04240106
What this trial is testing

Niraparib Plus Aromatase Inhibitors for Luminal-like(HER2-,ER+) and gBRCA or HDR+ Metastatic Breast Cancer (LUZERN)

Who this might be right for
Breast CancerBreast Cancer Metastatic
MedSIR 14
Testing effectiveness (Phase 2)Study completedNCT03025035
What this trial is testing

Pembrolizumab in Combination With Olaparib in Advanced BRCA-mutated or HDR-defect Breast Cancer

Who this might be right for
Breast Cancer
Yuan Yuan 14
Large-scale testing (Phase 3)Looking for participantsNCT06952803
What this trial is testing

Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Who this might be right for
Prostate Cancer
AstraZeneca 700
Testing effectiveness (Phase 2)Study completedNCT02282345
What this trial is testing

Talazoparib Before Standard Therapy in Treating Patients With Invasive, BRCA-Mutated Breast Cancer

Who this might be right for
Breast AdenocarcinomaDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+2 more
M.D. Anderson Cancer Center 36
Not applicableActive Not RecruitingNCT05748353
What this trial is testing

Endocrine Disruptors and Life STILe in Breast Cancer Development

Who this might be right for
Breast CancerBRCA1 MutationBRCA2 Mutation+3 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 275
Early research (Phase 1)Study completedNCT01445418
What this trial is testing

AZD2281 Plus Carboplatin to Treat Breast and Ovarian Cancer

Who this might be right for
Breast CancerOvarian Cancer
National Cancer Institute (NCI) 103
Not applicableUnknownNCT01329068
What this trial is testing

Patient Empowerment by Group Medical Consultations

Who this might be right for
Breast CancerBRCA Mutation
Radboud University Medical Center 320
Early research (Phase 1)Study completedNCT01339650
What this trial is testing

Study of ABT-767 in Subjects With Breast Cancer 1 and Breast Cancer 2 (BRCA 1 and BRCA 2) Mutations and Solid Tumors or High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Fallopian TubePrimary Peritoneal CancerSolid Tumors (e.g. Breast, Ovarian, Prostate, or Pancreatic) and Ovarian
AbbVie (prior sponsor, Abbott) 93
Not applicableUnknownNCT01034891
What this trial is testing

Women At Risk: The High Risk Breast Cancer Program

Who this might be right for
Breast Cancer
New York Presbyterian Hospital 2,000
Early research (Phase 1)Study completedNCT01104259
What this trial is testing

Veliparib, Cisplatin, and Vinorelbine Ditartrate in Treating Patients With Recurrent and/or Metastatic Breast Cancer

Who this might be right for
Estrogen Receptor-negative Breast CancerHER2-negative Breast CancerHereditary Breast/Ovarian Cancer - BRCA1+6 more
University of Washington 50
Large-scale testing (Phase 3)Active Not RecruitingNCT04915755
What this trial is testing

Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease

Who this might be right for
Neoplasms, Breast
GlaxoSmithKline 40
Testing effectiveness (Phase 2)Looking for participantsNCT05834582
What this trial is testing

Neoadjuvant Fluzoparib in Germline BRCA-mutated Three-negative Breast Cancer Breast Cancer

Who this might be right for
TNBC - Triple-Negative Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 60
Testing effectiveness (Phase 2)Looking for participantsNCT06516289
What this trial is testing

Neoadjuvant Treatment of gBRCA-Mutated HER2-Negative Breast Cancer With HRS-1167 and Famitinib ± Camrelizumab

Who this might be right for
BRCA-Mutated Breast CarcinomaHER2-negative Breast Cancer
Fudan University 130
Not applicableStudy completedNCT02151747
What this trial is testing

Testing BRCA 1/2 Mutation Using Next Generation Sequencing

Who this might be right for
Breast NeoplasmsBreast Cancer
Severance Hospital 12
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