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Results for “BRCA-Mutated Ovarian Carcinoma”

73 trials

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Showing 20 of 73 results

Not applicableUnknownNCT04651933
What this trial is testing

A Training Set for the HRD Model in EOC

Who this might be right for
Epithelial Ovarian CancerBRCA MutationLoss of Heterozygosity+3 more
Lei Li 200
Early research (Phase 1)Active Not RecruitingNCT04673448
What this trial is testing

Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8BRCA-Associated Malignant Neoplasm+24 more
University of Washington 18
Testing effectiveness (Phase 2)Study completedNCT02983799
What this trial is testing

Olaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumor Status

Who this might be right for
Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity
AstraZeneca 272
Large-scale testing (Phase 3)Study completedNCT02282020
What this trial is testing

Olaparib Treatment in Relapsed Germline Breast Cancer Susceptibility Gene (BRCA) Mutated Ovarian Cancer Patients Who Have Progressed at Least 6 Months After Last Platinum Treatment and Have Received at Least 2 Prior Platinum Treatments

Who this might be right for
Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity
AstraZeneca 266
Early research (Phase 1)Study completedNCT04672460
What this trial is testing

A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsSolid TumorsOvarian Cancer+5 more
Pfizer 73
Not applicableStudy completedNCT05775549
What this trial is testing

Characterize the Outcomes of Olaparib Maintenance Monotherapy in Newly Diagnosed BRCAwt Ovarian Cancer

Who this might be right for
Advanced Ovarian Cancer
AstraZeneca 24
Not applicableActive Not RecruitingNCT06497270
What this trial is testing

A 3D Bioprinted Hormone-producing Model for BRCA Mutated Patients After Risk Reducing Surgery: the DISC-OVARY Trial

Who this might be right for
BRCA MutationEstrogen DeficiencySurgical Menopause+3 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 3
Large-scale testing (Phase 3)Active Not RecruitingNCT03740165
What this trial is testing

Study of Chemotherapy With Pembrolizumab (MK-3475) Followed by Maintenance With Olaparib (MK-7339) for the First-Line Treatment of Women With BRCA Non-mutated Advanced Epithelial Ovarian Cancer (EOC) (MK-7339-001/KEYLYNK-001/ENGOT-ov43/GOG-3036)

Who this might be right for
Ovarian CancerFallopian Tube CancerPeritoneal Neoplasms
Merck Sharp & Dohme LLC 1,367
Early research (Phase 1)Not Yet RecruitingNCT07088588
What this trial is testing

Study of SYN608 for the Treatment of Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid CancerMetastatic Solid TumorOvarian Cancer+3 more
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd 105
Early research (Phase 1)Looking for participantsNCT06666270
What this trial is testing

Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid CancerMetastatic Solid TumorOvarian Cancer+4 more
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd 30
Not applicableActive Not RecruitingNCT01608074
What this trial is testing

Radical Fimbriectomy for Young BRCA Mutation Carriers

Who this might be right for
BRCA1 MutationBRCA2 MutationHereditary Breast and Ovarian Cancer
Centre Oscar Lambret 123
Post-approval studies (Phase 4)Study completedNCT02476968
What this trial is testing

To Assess the Efficacy and Safety of Olaparib Maintenance Monotherapy in the Treatment of Ovarian Cancer

Who this might be right for
BRCA or HRR+ Mutated Ovarian Cancer Patients
AstraZeneca 181
Not applicableActive Not RecruitingNCT04009148
What this trial is testing

Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome

Who this might be right for
BRCA-Mutated Ovarian CarcinomaBRIP1 Gene MutationMSH2 A636P+5 more
NYU Langone Health 118
Large-scale testing (Phase 3)UnknownNCT03162276
What this trial is testing

Trial of Inquiry Based Stress Reduction (IBSR) Program for BRCA1/2 Mutation Carriers

Who this might be right for
Hereditary Breast and Ovarian Cancer Syndrome
Sheba Medical Center 118
Large-scale testing (Phase 3)Study completedNCT03402841
What this trial is testing

Multicentre Study of Olaparib Maintenance Monotherapy in Platinum Sensitive Relapsed Non gBRCAm Ovarian Cancer Patients

Who this might be right for
Non-Germline BRCA Mutated Ovarian Cancer
AstraZeneca 279
Not applicableUnknownNCT05409222
What this trial is testing

Study of Quality of Life Post Salpingo-oophorectomy in BRCA1/2 & PALB2 Mutation Carriers (BRCA-HRT)

Who this might be right for
Hereditary Breast and Ovarian Cancer
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 45
Testing effectiveness (Phase 2)Study completedNCT00664781
What this trial is testing

Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer

Who this might be right for
brca1 Mutation Carrierbrca2 Mutation CarrierBreast Cancer+1 more
Cancer Research UK 78
Large-scale testing (Phase 3)Active Not RecruitingNCT01874353
What this trial is testing

Olaparib Treatment in BRCA Mutated Ovarian Cancer Patients After Complete or Partial Response to Platinum Chemotherapy

Who this might be right for
Platinum SensitiveBRCA MutatedRelapsed Ovarian Cancer+1 more
AstraZeneca 327
Not applicableActive Not RecruitingNCT01907789
What this trial is testing

Prophylactic Salpingectomy With Delayed Oophorectomy

Who this might be right for
Ovarian Carcinoma
M.D. Anderson Cancer Center 80
Not applicableStudy completedNCT04532645
What this trial is testing

Olaparib Real-world Utilization and Clinical Outcomes in France, Italy, and the UK

Who this might be right for
Ovary Cancer
AstraZeneca 342
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