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Results for “BRCA1 Mutation”

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Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT05694715
What this trial is testing

Combination Therapy in Cancers With Mutations in DNA Repair Genes

Who this might be right for
Metastatic Solid TumorBRCA1 MutationBRCA2 Mutation+2 more
University of California, San Francisco 24
Not applicableEnded earlyNCT04668521
What this trial is testing

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection

Who this might be right for
Adnexal MassGermline BRCA1 Gene MutationGermline BRCA2 Gene Mutation+1 more
Aspira Women's Health 215
Not applicableLooking for participantsNCT00823654
What this trial is testing

Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 609
Testing effectiveness (Phase 2)Study completedNCT01074970
What this trial is testing

PARP Inhibition for Triple Negative Breast Cancer (ER-/PR-/HER2-)With BRCA1/2 Mutations

Who this might be right for
Breast Cancer
Hoosier Cancer Research Network 135
Testing effectiveness (Phase 2)Active Not RecruitingNCT02393794
What this trial is testing

Cisplatin Plus Romidepsin & Nivolumab in Locally Recurrent or Metastatic Triple Negative Breast Cancer (TNBC)

Who this might be right for
Triple-Negative Breast CancerBreast Cancer
Priyanka Sharma 51
Early research (Phase 1)Study completedNCT01104259
What this trial is testing

Veliparib, Cisplatin, and Vinorelbine Ditartrate in Treating Patients With Recurrent and/or Metastatic Breast Cancer

Who this might be right for
Estrogen Receptor-negative Breast CancerHER2-negative Breast CancerHereditary Breast/Ovarian Cancer - BRCA1+6 more
University of Washington 50
Not applicableStudy completedNCT03066856
What this trial is testing

Dietary Intervention and BRCA Penetrance

Who this might be right for
Dietary ModificationBRCA1 MutationBRCA2 Mutation+1 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 502
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439227
What this trial is testing

Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 33
Large-scale testing (Phase 3)Ended earlyNCT00617656
What this trial is testing

Study to Evaluate Treatment Customized According to RAP80 and BRCA1 in Patients With Advanced Lung Carcinoma

Who this might be right for
Non Small Cell Lung CancerBRCA1 Mutation
Spanish Lung Cancer Group 382
Testing effectiveness (Phase 2)UnknownNCT03337087
What this trial is testing

Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer

Who this might be right for
Metastatic Biliary Tract CarcinomaMetastatic Colorectal CarcinomaMetastatic Gastroesophageal Junction Adenocarcinoma+6 more
Academic and Community Cancer Research United 18
Early research (Phase 1)UnknownNCT02225015
What this trial is testing

Cancer Prevention in Women With a BRCA Mutation

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene MutationBreast Cancer+1 more
Women's College Hospital 300
Not applicableActive Not RecruitingNCT03351803
What this trial is testing

BRCA Founder OutReach (BFOR) Study

Who this might be right for
BRCA1 MutationBRCA2 Mutation
Memorial Sloan Kettering Cancer Center 5,412
Testing effectiveness (Phase 2)Study completedNCT01506609
What this trial is testing

Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide (TMZ) or In Combination With Carboplatin and Paclitaxel Versus Placebo in Participants With Breast Cancer Gene (BRCA)1 and BRCA2 Mutation and Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AbbVie 294
Not applicableActive Not RecruitingNCT02783664
What this trial is testing

Evaluating the Effects of Genetic Testing on Patients' Stress Levels

Who this might be right for
Breast Cancer
Medical College of Wisconsin 164
Not applicableLooking for participantsNCT04960839
What this trial is testing

Prophylactic Irradiation to the Contralateral Breast for BCAs Patients

Who this might be right for
Breast Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine 323
Testing effectiveness (Phase 2)Active Not RecruitingNCT03428802
What this trial is testing

Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene MutationLocally Advanced Solid Neoplasm+17 more
Rutgers, The State University of New Jersey 21
Post-approval studies (Phase 4)Active Not RecruitingNCT05457257
What this trial is testing

Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
AstraZeneca 43
Not applicableStudy completedNCT00579007
What this trial is testing

Decision-making Regarding Prophylactic Mastectomy and Oophorectomy in Women Seeking Genetic Counseling and Testing for BRCA1/2 Mutations

Who this might be right for
Breast CancerOvarian Cancer
Memorial Sloan Kettering Cancer Center 224
Large-scale testing (Phase 3)UnknownNCT04296370
What this trial is testing

Fluzoparib±Apatinib Versus Chemotherapy Treatment of Physician's Choice in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation

Who this might be right for
Treatment in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation
Jiangsu HengRui Medicine Co., Ltd. 474
Not applicableStudy completedNCT00582803
What this trial is testing

Adherence to Intensive Surveillance for Hereditary Breast Cancer

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 85
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