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Results for “BRCA1 Mutations”

280 trials

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Showing 20 of 280 results

Not applicableStudy completedNCT03889171
What this trial is testing

Comparison to Psychological, Medical and Emotional Influencing Communication and Achievement Factors to Oncogenetics Tests

Who this might be right for
CancerColorectal CancerBreast Cancer+1 more
University Hospital, Montpellier 200
Not applicableActive Not RecruitingNCT02783664
What this trial is testing

Evaluating the Effects of Genetic Testing on Patients' Stress Levels

Who this might be right for
Breast Cancer
Medical College of Wisconsin 164
Not applicableLooking for participantsNCT05769517
What this trial is testing

Prediction of Germline BRCA 1/2 Genes From Healthy Ovaries

Who this might be right for
BRCA MutationOvarian CancerUltrasound Therapy; Complications
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 6,465
Not applicableActive Not RecruitingNCT01907789
What this trial is testing

Prophylactic Salpingectomy With Delayed Oophorectomy

Who this might be right for
Ovarian Carcinoma
M.D. Anderson Cancer Center 80
Not applicableTemporarily pausedNCT02993068
What this trial is testing

Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

Who this might be right for
BARD1 Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+12 more
M.D. Anderson Cancer Center 5,200
Testing effectiveness (Phase 2)Study completedNCT01540565
What this trial is testing

Veliparib in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
BRCA1 Mutation CarrierBRCA2 Mutation CarrierOvarian Epithelial Tumor+3 more
National Cancer Institute (NCI) 52
Not applicableActive Not RecruitingNCT04499534
What this trial is testing

BRCA1/2 Flu Vaccine

Who this might be right for
BRCA1 MutationBRCA2 Mutation
Abramson Cancer Center at Penn Medicine 50
Testing effectiveness (Phase 2)WithdrawnNCT06392841
What this trial is testing

Niraparib, Abiraterone Acetate and Prednisone for mHSPC With Deleterious Homologous Recombination Repair Alterations

Who this might be right for
Metastatic Hormone-sensitive Prostate Cancer (mHSPC)Deleterious HRR Gene MutationBRCA1 Gene Mutation+7 more
Qian Qin
Testing effectiveness (Phase 2)Looking for participantsNCT05806515
What this trial is testing

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

Who this might be right for
Prostate AdenocarcinomaStage IIIB Prostate Cancer AJCC v8Stage IIIC Prostate Cancer AJCC v8
SWOG Cancer Research Network 44
Not applicableStudy completedNCT04108117
What this trial is testing

Surgical and Oncologic Outcomes After Robotic Nipple Sparing Mastectomy and Immediate Reconstruction

Who this might be right for
Postoperative ComplicationsRecurrenceBreast Neoplasms+5 more
Severance Hospital 659
Not applicableStudy completedNCT04257474
What this trial is testing

Barriers to Screening Breast MRI Utilization Among Patients at Elevated Risk

Who this might be right for
Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 265
Not applicableWithdrawnNCT00084370
What this trial is testing

Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who Are Undergoing Prophylactic Oophorectomy

Who this might be right for
brca1 Mutation Carrierbrca2 Mutation CarrierOvarian Cancer
University of Alabama at Birmingham
Large-scale testing (Phase 3)Study completedNCT02163694
What this trial is testing

Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AbbVie 513
Not applicableStudy completedNCT02197000
What this trial is testing

A Nutritional Intervention to Decrease Breast Density Among Female BRCA (BReast CAncer Susceptibility Gene) Carriers

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene Mutation
Rabin Medical Center 23
Not applicableActive Not RecruitingNCT02760849
What this trial is testing

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Who this might be right for
Deleterious BARD1 Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+11 more
M.D. Anderson Cancer Center 374
Not applicableLooking for participantsNCT04431024
What this trial is testing

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

Who this might be right for
Familial CancerBRCA1-Associated Protein-1 (BAP1) MutationsTumor Predisposition Syndrome (TPDS)+1 more
National Cancer Institute (NCI) 300
Not applicableLooking for participantsNCT02478892
What this trial is testing

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

Who this might be right for
Pancreatic Cancer
Abramson Cancer Center at Penn Medicine 200
Not applicableLooking for participantsNCT04251052
What this trial is testing

Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Who this might be right for
Ovarian Carcinoma
NRG Oncology 1,956
Early research (Phase 1)Active Not RecruitingNCT05787587
What this trial is testing

PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsBreast CancerOvarian Cancer+6 more
IDEAYA Biosciences 216
Testing effectiveness (Phase 2)Study completedNCT01611727
What this trial is testing

Open-Label,Non-Randomized Trial of Cisplatin Chemotherapy in BRCA1-Positive Metastatic Breast Cancer Patients

Who this might be right for
BRCA1 MutationMetastatic Breast Cancer
Pomeranian Medical University Szczecin 20
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