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Results for “BRCA1 Syndrome”

57 trials

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Showing 20 of 57 results

Testing effectiveness (Phase 2)Study completedNCT02797977
What this trial is testing

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Who this might be right for
Advanced Solid Tumors
Sierra Oncology LLC - a GSK company 153
Not applicableActive Not RecruitingNCT02760849
What this trial is testing

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Who this might be right for
Deleterious BARD1 Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+11 more
M.D. Anderson Cancer Center 374
Testing effectiveness (Phase 2)Study completedNCT02797964
What this trial is testing

A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)
Sierra Oncology LLC - a GSK company 107
Not applicableActive Not RecruitingNCT02653105
What this trial is testing

Women at Risk of Breast Cancer and OLFM4

Who this might be right for
Hereditary Breast and Ovarian Cancer Syndrome
Institut Cancerologie de l'Ouest 150
Not applicableActive Not RecruitingNCT02206360
What this trial is testing

Pancreatic Cancer Early Detection Program

Who this might be right for
Pancreatic CancerPancreas CancerPancreatic Adenocarcinoma+8 more
White Plains Hospital 100
Large-scale testing (Phase 3)Study completedNCT00673335
What this trial is testing

Letrozole in Preventing Breast Cancer in Postmenopausal Women With a BRCA1 or BRCA2 Mutation

Who this might be right for
brca1 Mutation Carrierbrca2 Mutation CarrierBreast Cancer+1 more
UNICANCER 170
Not applicableActive Not RecruitingNCT02194387
What this trial is testing

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

Who this might be right for
Body Mass Index 25 or GreaterBRCA1 Gene MutationBRCA2 Gene Mutation+8 more
M.D. Anderson Cancer Center 337
Not applicableLooking for participantsNCT02516540
What this trial is testing

Efficacy of Lifestyle Intervention in BRCA1/2 Mutation Carriers

Who this might be right for
Hereditary Breast and Ovarian Cancer
Technical University of Munich 600
Not applicableLooking for participantsNCT06726642
What this trial is testing

CfDNA in Hereditary And High-risk Malignancies 2

Who this might be right for
Hereditary Cancer Syndrome
University Health Network, Toronto 1,000
Not applicableLooking for participantsNCT05129605
What this trial is testing

Prostate Cancer Genetic Risk Evaluation and Screening Study

Who this might be right for
Prostatic NeoplasmProstate CancerBRCA2 Mutation+5 more
Massachusetts General Hospital 400
Large-scale testing (Phase 3)Study completedNCT00685256
What this trial is testing

Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)
Georgetown University 245
Testing effectiveness (Phase 2)Study completedNCT02978495
What this trial is testing

Neoadjuvant Carboplatin in Triple Negative Breast Cancer

Who this might be right for
BRCA1 Hereditary Breast and Ovarian Cancer Syndrome
Barretos Cancer Hospital 154
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06654050
What this trial is testing

Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma

Who this might be right for
MesotheliomaMalignant Mesothelioma (MM)Early-stage Mesothelioma+3 more
National Cancer Institute (NCI) 15
Not applicableLooking for participantsNCT04494945
What this trial is testing

Identifying and Caring for Individuals With Inherited Cancer Syndrome

Who this might be right for
BRCA1/2-Associated Hereditary Breast and Ovarian Cancer SyndromeBreast Ductal Carcinoma In SituHematopoietic and Lymphoid System Neoplasm+3 more
OHSU Knight Cancer Institute 27,500
Not applicableStudy completedNCT00001496
What this trial is testing

Establishment of Normal Breast Epithelial Cell Lines From Patients at High Risk for Breast Cancer

Who this might be right for
Breast NeoplasmHereditary Neoplastic Syndrome
National Cancer Institute (NCI) 50
Not applicableEnded earlyNCT04668521
What this trial is testing

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection

Who this might be right for
Adnexal MassGermline BRCA1 Gene MutationGermline BRCA2 Gene Mutation+1 more
Aspira Women's Health 215
Testing effectiveness (Phase 2)Study completedNCT01367639
What this trial is testing

Trial of Inquiry Based Stress Reduction (IBSR) Program for BRCA1/2 Mutation Carriers

Who this might be right for
Hereditary Breast and Ovarian Cancer Syndrome
Sheba Medical Center 67
Not applicableStudy completedNCT02451735
What this trial is testing

Genetic Counseling for Breast Cancer Survivors (GC for BC)

Who this might be right for
Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 157
Not applicableStudy completedNCT03510689
What this trial is testing

Genetics and Heart Health After Cancer Therapy

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, Brca2)Heart Diseases+1 more
Abramson Cancer Center at Penn Medicine 79
Not applicableUnknownNCT01273909
What this trial is testing

Outcomes After Perforator Flap Reconstruction for Breast Reconstruction and/or Lymphedema Treatment

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)Acquired Lymphedema+1 more
The National Institute of Lymphology 1,000
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