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Results for “BRCA1 Syndrome”

60 trials

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Showing 20 of 60 results

Testing effectiveness (Phase 2)Study completedNCT02978495
What this trial is testing

Neoadjuvant Carboplatin in Triple Negative Breast Cancer

Who this might be right for
BRCA1 Hereditary Breast and Ovarian Cancer Syndrome
Barretos Cancer Hospital 154
Not applicableEnded earlyNCT01103128
What this trial is testing

Validation of a Mouse Model of Pancreatic Carcinogenesis

Who this might be right for
Pancreatic Cancer
Columbia University 450
Not applicableActive Not RecruitingNCT04261972
What this trial is testing

Cell-free DNA in Hereditary And High-Risk Malignancies 1

Who this might be right for
Hereditary Cancer Syndrome
University Health Network, Toronto 1,416
Not applicableNot Yet RecruitingNCT07542405
What this trial is testing

A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families

Who this might be right for
BRCA1-Related Hereditary Breast and Ovarian Cancer SyndromeBRCA2-Related Hereditary Breast and Ovarian Cancer SyndromeHereditary Neoplastic Syndrome+1 more
University of Michigan Rogel Cancer Center 150
Early research (Phase 1)Study completedNCT00892736
What this trial is testing

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Who this might be right for
Basal-Like Breast CarcinomaBRCA1 Mutation CarrierBRCA2 Mutation Carrier+14 more
National Cancer Institute (NCI) 98
Not applicableLooking for participantsNCT03702309
What this trial is testing

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Who this might be right for
CancerBreast CancerLung Cancer+15 more
University Health Network, Toronto 2,500
Large-scale testing (Phase 3)Study completedNCT00685256
What this trial is testing

Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)
Georgetown University 245
Testing effectiveness (Phase 2)Study completedNCT00253539
What this trial is testing

Arzoxifene or Tamoxifen in Preventing Breast Cancer in Premenopausal Women at High Risk for Breast Cancer

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)
The Cleveland Clinic 3
Not applicableNot Yet RecruitingNCT07764744
What this trial is testing

Ovarian Cancer Liquid Biopsy for Early Assessment & Detection in Individuals With BRCA1/2 Pathogenic Variants

Who this might be right for
Ovarian NeoplasmsBRCA 1 Gene MutationBRCA 2 Gene Mutation+2 more
Weill Medical College of Cornell University 70
Not applicableEnded earlyNCT04668521
What this trial is testing

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection

Who this might be right for
Adnexal MassGermline BRCA1 Gene MutationGermline BRCA2 Gene Mutation+1 more
Aspira Women's Health 215
Not applicableEnrolling By InvitationNCT06914726
What this trial is testing

Patient Centered Clinical Decision Support for Hereditary Cancer Syndromes

Who this might be right for
Hereditary Breast/Ovarian Cancer (brca1, brca2)Lynch SyndromeGenetic Variation+2 more
HealthPartners Institute 2,488
Not applicableStudy completedNCT03510689
What this trial is testing

Genetics and Heart Health After Cancer Therapy

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, Brca2)Heart Diseases+1 more
Abramson Cancer Center at Penn Medicine 79
Not applicableLooking for participantsNCT05129605
What this trial is testing

Prostate Cancer Genetic Risk Evaluation and Screening Study

Who this might be right for
Prostatic NeoplasmProstate CancerBRCA2 Mutation+5 more
Massachusetts General Hospital 400
Not applicableActive Not RecruitingNCT02653105
What this trial is testing

Women at Risk of Breast Cancer and OLFM4

Who this might be right for
Hereditary Breast and Ovarian Cancer Syndrome
Institut Cancerologie de l'Ouest 150
Testing effectiveness (Phase 2)Study completedNCT02797977
What this trial is testing

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Who this might be right for
Advanced Solid Tumors
Sierra Oncology LLC - a GSK company 153
Not applicableLooking for participantsNCT02705846
What this trial is testing

Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations

Who this might be right for
Prostate Cancer
Institute of Cancer Research, United Kingdom 4,260
Not applicableStudy completedNCT02957981
What this trial is testing

The Genetic Education for Men Trial: Web-Based Education vs. Standard Care

Who this might be right for
Prostate CarcinomaBreast NeoplasmPancreatic Cancer+2 more
Georgetown University 63
Testing effectiveness (Phase 2)Looking for participantsNCT05960773
What this trial is testing

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

Who this might be right for
MesotheliomaMalignant Mesothelioma (MM)Early-stage Mesothelioma+3 more
National Cancer Institute (NCI) 15
Not applicableLooking for participantsNCT07436312
What this trial is testing

Impact of Consumption of Ultra-processed Foods in Individuals at High Risk of Cancer

Who this might be right for
Breast CancerPancreas CancerColon Cancer+3 more
Gustave Roussy, Cancer Campus, Grand Paris 170
Not applicableStudy completedNCT02206360
What this trial is testing

Pancreatic Cancer Early Detection Program

Who this might be right for
Pancreatic CancerPancreas CancerPancreatic Adenocarcinoma+8 more
White Plains Hospital 181
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