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Results for “BRCA2”

257 trials

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Showing 20 of 257 results

Not applicableWithdrawnNCT00899145
What this trial is testing

Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation Carriers

Who this might be right for
BRCA1 Mutation CarrierBRCA2 Mutation CarrierBreast Carcinoma
Gynecologic Oncology Group
Not applicableActive Not RecruitingNCT02321228
What this trial is testing

Early Salpingectomy (Tubectomy) With Delayed Oophorectomy in BRCA1/2 Gene Mutation Carriers

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene MutationOvarian Cancer
University Medical Center Nijmegen 510
Very early researchActive Not RecruitingNCT03943173
What this trial is testing

Olaparib in Treating Patients With Newly Diagnosed BRCA-Mutant Ovarian, Primary Peritoneal, or Fallopian Cancer Before Surgery

Who this might be right for
BRCA-Mutated Ovarian CarcinomaBRCA1 Gene MutationBRCA2 Gene Mutation+28 more
M.D. Anderson Cancer Center 15
Testing effectiveness (Phase 2)Study completedNCT00677079
What this trial is testing

Single Arm Study of BSI-201 in Patients With BRCA-1 or BRCA-2 Associated Advanced Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Primary Peritoneal CancerAdvanced Epithelial Ovarian Cancer
Sanofi 12
Not applicableActive Not RecruitingNCT02760849
What this trial is testing

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Who this might be right for
Deleterious BARD1 Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+11 more
M.D. Anderson Cancer Center 374
Testing effectiveness (Phase 2)Study completedNCT02401347
What this trial is testing

Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumors

Who this might be right for
Advanced Breast CancerHER2/Neu NegativeTriple-Negative Breast Cancer
Melinda Telli 21
Testing effectiveness (Phase 2)Study completedNCT01482715
What this trial is testing

Oral Rucaparib in Patients With a Solid Tumor (Phase I) or With gBRCA Mutation Ovarian Cancer (Phase II)

Who this might be right for
Ovarian CancerFallopian Tube CancerPeritoneal Cancer+1 more
pharmaand GmbH 136
Testing effectiveness (Phase 2)Looking for participantsNCT06201234
What this trial is testing

Evaluating the Addition of Elacestrant (Oral SERD) to Olaparib (PARP-inhibitor) in Patients With Advanced/Metastatic HR+/HER2- Breast Cancer

Who this might be right for
Hormone Receptor Positive HER-2 Negative Breast CancerAdvanced or Metastatic Breast CancerBRCA1 Mutation+1 more
GBG Forschungs GmbH 176
Not applicableEnrolling By InvitationNCT06914726
What this trial is testing

Patient Centered Clinical Decision Support for Hereditary Cancer Syndromes

Who this might be right for
Hereditary Breast/Ovarian Cancer (brca1, brca2)Lynch SyndromeGenetic Variation+2 more
HealthPartners Institute 2,488
Not applicableStudy completedNCT02154633
What this trial is testing

Lessons Learned From the Family Gene Toolkit

Who this might be right for
Women With BRCA 1 or BRCA 2 MutationNon-tested Female Family Members
University of Michigan 13
Not applicableEnded earlyNCT01374685
What this trial is testing

Family Communication of Hereditary Breast and Ovarian Cancer Risk Among African Americans

Who this might be right for
Ovarian NeoplasmCancer GeneticsBreast Cancer
National Human Genome Research Institute (NHGRI) 8
Not applicableActive Not RecruitingNCT01907789
What this trial is testing

Prophylactic Salpingectomy With Delayed Oophorectomy

Who this might be right for
Ovarian Carcinoma
M.D. Anderson Cancer Center 80
Not applicableStudy completedNCT00001468
What this trial is testing

Outcomes of Education and Counseling for BRCA1 Testing

Who this might be right for
Breast NeoplasmsOvarian Neoplasms
National Human Genome Research Institute (NHGRI) 1,500
Not applicableUnknownNCT03319290
What this trial is testing

Increase Surveillance for Breast and Ovarian Cancers, Also to Determine Targeted Risk-reducing and Preventative Strategies

Who this might be right for
Hereditary Cancer
Data Collection Analysis Business Management 2,000
Testing effectiveness (Phase 2)UnknownNCT04556071
What this trial is testing

Efficacy and Safety of Niraparib Combined With Bevacizumab in Platinum Refractory/Resistant Recurrent Ovarian Cancer

Who this might be right for
Ovarian NeoplasmsFallopian Tube NeoplasmsEndocrine Gland Neoplasms+21 more
Xiaoxiang Chen 32
Not applicableActive Not RecruitingNCT04474834
What this trial is testing

Genetic Risk Estimations for Influencing Decision Making in Women at High Risk of Breast Cancer, GENRE 2 Study

Who this might be right for
Breast Cancer
Mayo Clinic 737
Testing effectiveness (Phase 2)Active Not RecruitingNCT02571725
What this trial is testing

PARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian Cancer

Who this might be right for
Ovarian CancerFallopian Tube CancerPeritoneal Neoplasms
New Mexico Cancer Research Alliance 50
Not applicableActive Not RecruitingNCT04613440
What this trial is testing

FaCT Trial (Facilitated Cascade Testing Trial)

Who this might be right for
BRCA1 MutationBRCA2 Mutation
Weill Medical College of Cornell University 524
Not applicableActive Not RecruitingNCT02530008
What this trial is testing

Breast Cancer 2-PREVENT Translational Center of Excellence (TCE) - Metastatic Markers of Recurrent Tumor Phenotype for Breast Cancer

Who this might be right for
Women With Suspected or Confirmed Recurrent Breast Cancer
Abramson Cancer Center at Penn Medicine 600
Not applicableUnknownNCT02959398
What this trial is testing

Evaluation of Tomosynthesis for Characterization and the Management of Breast Lesions

Who this might be right for
Breast NeoplasmsTomosynthesisBRCA1 Protein+1 more
Assistance Publique - Hôpitaux de Paris 2,000
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