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Results for “BRCA2”

255 trials

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Showing 20 of 255 results

Testing effectiveness (Phase 2)Study completedNCT05054725
What this trial is testing

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Who this might be right for
Non-Small Cell Lung Cancer
Revolution Medicines, Inc. 47
Early research (Phase 1)Study completedNCT00892736
What this trial is testing

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Who this might be right for
Basal-Like Breast CarcinomaBRCA1 Mutation CarrierBRCA2 Mutation Carrier+14 more
National Cancer Institute (NCI) 98
Not applicableActive Not RecruitingNCT02760849
What this trial is testing

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Who this might be right for
Deleterious BARD1 Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+11 more
M.D. Anderson Cancer Center 374
Not applicableStudy completedNCT03889171
What this trial is testing

Comparison to Psychological, Medical and Emotional Influencing Communication and Achievement Factors to Oncogenetics Tests

Who this might be right for
CancerColorectal CancerBreast Cancer+1 more
University Hospital, Montpellier 200
Early research (Phase 1)Looking for participantsNCT05694715
What this trial is testing

Combination Therapy in Cancers With Mutations in DNA Repair Genes

Who this might be right for
Metastatic Solid TumorBRCA1 MutationBRCA2 Mutation+2 more
University of California, San Francisco 24
Not applicableNot Yet RecruitingNCT07436312
What this trial is testing

Impact of Consumption of Ultra-processed Foods in Individuals at High Risk of Cancer

Who this might be right for
Breast CancerPancreas CancerColon Cancer+3 more
Gustave Roussy, Cancer Campus, Grand Paris 170
Large-scale testing (Phase 3)UnknownNCT04055038
What this trial is testing

Efficacy of Platinum-based Chemotherapy in Platinum-resistant Ovarian Cancer) (EPITOC)

Who this might be right for
Ovarian CancerOvarian NeoplasmsSerous Adenocarcinoma+3 more
Blokhin's Russian Cancer Research Center 164
Testing effectiveness (Phase 2)WithdrawnNCT03432676
What this trial is testing

Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer

Who this might be right for
ATM Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+7 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT04548752
What this trial is testing

Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

Who this might be right for
Metastatic Pancreatic AdenocarcinomaStage IV Pancreatic Cancer AJCC v8
National Cancer Institute (NCI) 88
Large-scale testing (Phase 3)Study completedNCT00685256
What this trial is testing

Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)
Georgetown University 245
Not applicableTemporarily pausedNCT02993068
What this trial is testing

Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

Who this might be right for
BARD1 Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+12 more
M.D. Anderson Cancer Center 5,200
Not applicableEnded earlyNCT03503097
What this trial is testing

Genetic Testing for Men With Metastatic Prostate Cancer

Who this might be right for
Metastatic Prostate CarcinomaStage IV Prostate Cancer AJCC v8Stage IVB Prostate Cancer AJCC v8
University of Washington 799
Testing effectiveness (Phase 2)Ended earlyNCT03140670
What this trial is testing

Maintenance Rucaparib in BRCA1, BRCA2 or PALB2 Mutated Pancreatic Cancer That Has Not Progressed on Platinum-based Therapy

Who this might be right for
Pancreatic Cancer
Abramson Cancer Center at Penn Medicine 46
Not applicableLooking for participantsNCT02775461
What this trial is testing

Pancreas Registry and High Risk Registry

Who this might be right for
Pancreas CancerPancreatitisChronic Pancreatitis+3 more
Icahn School of Medicine at Mount Sinai 1,368
Not applicableStudy completedNCT00590109
What this trial is testing

Germline BRCA1 and BRCA2 Mutations in Jewish Women Affected by Breast Cancer

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 383
Not applicableActive Not RecruitingNCT02783664
What this trial is testing

Evaluating the Effects of Genetic Testing on Patients' Stress Levels

Who this might be right for
Breast Cancer
Medical College of Wisconsin 164
Testing effectiveness (Phase 2)UnknownNCT01772979
What this trial is testing

Study With Trabectedin in BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype Ovarian Cancer

Who this might be right for
BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype
Catholic University of the Sacred Heart 100
Early research (Phase 1)Active Not RecruitingNCT03586661
What this trial is testing

Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Who this might be right for
Deleterious BRCA1 Gene MutationDeleterious BRCA2 Gene MutationEndometrial Adenocarcinoma+8 more
M.D. Anderson Cancer Center 31
Not applicableStudy completedNCT01992471
What this trial is testing

Multiplex Testing for Breast Cancer Susceptibility: A Pilot Study of Subject Preferences for Information and Responses After Testing

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 197
Not applicableStudy completedNCT02039388
What this trial is testing

Lavage of the Uterine Cavity for the Diagnosis of Serous Tubal Intraepithelial Carcinoma

Who this might be right for
Ovarian Epithelial CancerCarcinoma in SituOvarian Cancer
Medical University of Vienna 701
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