Not applicableActive Not RecruitingNCT04499534What this trial is testingBRCA1/2 Flu VaccineWho this might be right forBRCA1 MutationBRCA2 Mutation Abramson Cancer Center at Penn Medicine 50
Early research (Phase 1)Ended earlyNCT01233505What this trial is testingVeliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid TumorsWho this might be right forAdenocarcinoma of the PancreasAdenocarcinoma of the StomachBRCA1 Mutation Carrier+23 more National Cancer Institute (NCI) 16
Large-scale testing (Phase 3)Active Not RecruitingNCT01905046What this trial is testingMetformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast CancerWho this might be right forAtypical Ductal Breast HyperplasiaBRCA1 Mutation CarrierBRCA2 Mutation Carrier+2 more Alliance for Clinical Trials in Oncology 86
Not applicableActive Not RecruitingNCT01608074What this trial is testingRadical Fimbriectomy for Young BRCA Mutation CarriersWho this might be right forBRCA1 MutationBRCA2 MutationHereditary Breast and Ovarian Cancer Centre Oscar Lambret 123
Not applicableStudy completedNCT03684733What this trial is testingMagnetic Resonance Breast Tissue Characterisation to Improve Risk Stratification for Breast CancerWho this might be right forBRCA1 MutationBRCA2 MutationMammography+1 more Royal Marsden NHS Foundation Trust 28
Early research (Phase 1)Active Not RecruitingNCT04367675What this trial is testingINO 5401 Vaccination in BRCA1/2 Mutation CarriersWho this might be right forBRCA1/2 Mutation Abramson Cancer Center at Penn Medicine 44
Testing effectiveness (Phase 2)Study completedNCT00664781What this trial is testingRucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian CancerWho this might be right forbrca1 Mutation Carrierbrca2 Mutation CarrierBreast Cancer+1 more Cancer Research UK 78
Not applicableLooking for participantsNCT06792721What this trial is testingMEASUREMENT OF CIRCULATING MUTATION BURDENWho this might be right forBreast CarcinomaGenetic Predisposition to CancerBRCA Mutation+2 more Centre Francois Baclesse 30
Not applicableActive Not RecruitingNCT01907789What this trial is testingProphylactic Salpingectomy With Delayed OophorectomyWho this might be right forOvarian Carcinoma M.D. Anderson Cancer Center 80
Not applicableLooking for participantsNCT06127979What this trial is testingChanges in Ki67 Expression in People With Breast Cancer Receiving Endocrine Therapy Before SurgeryWho this might be right forBreast Cancer Memorial Sloan Kettering Cancer Center 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT00080756What this trial is testingDeslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This DiseaseWho this might be right forbrca1 Mutation Carrierbrca2 Mutation CarrierBreast Cancer City of Hope Medical Center 11
Not applicableStudy completedNCT03066856What this trial is testingDietary Intervention and BRCA PenetranceWho this might be right forDietary ModificationBRCA1 MutationBRCA2 Mutation+1 more Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 502
Not applicableStudy completedNCT01874184What this trial is testingGroup-Based Lifestyle Intervention in Measuring Biomarker Levels in Participants at High Risk for Breast CancerWho this might be right forAtypical Ductal Breast HyperplasiaAtypical Lobular Breast HyperplasiaBRCA1 Mutation Carrier+3 more University of Washington 17
Not applicableStudy completedNCT01097278What this trial is testingS0812 High Dose Cholecalciferol in Premenopausal Women at High-Risk for Breast CancerWho this might be right forbrca1 Mutation Carrierbrca2 Mutation CarrierBreast Cancer SWOG Cancer Research Network 208
Not applicableUnknownNCT00897455What this trial is testingStudying Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation CarriersWho this might be right forbrca1 Mutation Carrierbrca2 Mutation CarrierBreast Cancer Gynecologic Oncology Group 10,000
Not applicableWithdrawnNCT01409226What this trial is testing3.0 Tesla Magnetic Resonance Imaging for Breast Cancer Detection in High Risk WomenWho this might be right forBreast CancerBRCA1 MutationBRCA2 Mutation NYU Langone Health
Testing effectiveness (Phase 2)UnknownNCT01772979What this trial is testingStudy With Trabectedin in BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype Ovarian CancerWho this might be right forBRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype Catholic University of the Sacred Heart 100
Testing effectiveness (Phase 2)Study completedNCT01009788What this trial is testingABT-888 and Temozolomide for Metastatic Breast Cancer and BRCA1/2 Breast CancerWho this might be right forBreast CancerMetastatic Breast CancerBRCA1 Gene Mutation+1 more Steven J Isakoff, MD, PhD 63
Not applicableStudy completedNCT00986206What this trial is testingLysophosphatidic Acid Assay in Patients With Ovarian Cancer or Who Are at Risk for Ovarian CancerWho this might be right forbrca1 Mutation Carrierbrca2 Mutation CarrierOvarian Cancer Women and Infants Hospital of Rhode Island 525
Testing effectiveness (Phase 2)Active Not RecruitingNCT02571725What this trial is testingPARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian CancerWho this might be right forOvarian CancerFallopian Tube CancerPeritoneal Neoplasms New Mexico Cancer Research Alliance 50