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Results for “BRCA2 Syndrome”

39 trials

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Showing 20 of 39 results

Testing effectiveness (Phase 2)Study completedNCT02797977
What this trial is testing

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Who this might be right for
Advanced Solid Tumors
Sierra Oncology LLC - a GSK company 153
Not applicableActive Not RecruitingNCT02760849
What this trial is testing

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Who this might be right for
Deleterious BARD1 Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+11 more
M.D. Anderson Cancer Center 374
Testing effectiveness (Phase 2)Study completedNCT02797964
What this trial is testing

A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)
Sierra Oncology LLC - a GSK company 107
Large-scale testing (Phase 3)Study completedNCT00673335
What this trial is testing

Letrozole in Preventing Breast Cancer in Postmenopausal Women With a BRCA1 or BRCA2 Mutation

Who this might be right for
brca1 Mutation Carrierbrca2 Mutation CarrierBreast Cancer+1 more
UNICANCER 170
Not applicableActive Not RecruitingNCT02194387
What this trial is testing

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

Who this might be right for
Body Mass Index 25 or GreaterBRCA1 Gene MutationBRCA2 Gene Mutation+8 more
M.D. Anderson Cancer Center 337
Not applicableLooking for participantsNCT06726642
What this trial is testing

CfDNA in Hereditary And High-risk Malignancies 2

Who this might be right for
Hereditary Cancer Syndrome
University Health Network, Toronto 1,000
Not applicableLooking for participantsNCT05129605
What this trial is testing

Prostate Cancer Genetic Risk Evaluation and Screening Study

Who this might be right for
Prostatic NeoplasmProstate CancerBRCA2 Mutation+5 more
Massachusetts General Hospital 400
Large-scale testing (Phase 3)Study completedNCT00685256
What this trial is testing

Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)
Georgetown University 245
Not applicableEnded earlyNCT04668521
What this trial is testing

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection

Who this might be right for
Adnexal MassGermline BRCA1 Gene MutationGermline BRCA2 Gene Mutation+1 more
Aspira Women's Health 215
Not applicableStudy completedNCT02451735
What this trial is testing

Genetic Counseling for Breast Cancer Survivors (GC for BC)

Who this might be right for
Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 157
Not applicableStudy completedNCT03510689
What this trial is testing

Genetics and Heart Health After Cancer Therapy

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, Brca2)Heart Diseases+1 more
Abramson Cancer Center at Penn Medicine 79
Not applicableUnknownNCT01273909
What this trial is testing

Outcomes After Perforator Flap Reconstruction for Breast Reconstruction and/or Lymphedema Treatment

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)Acquired Lymphedema+1 more
The National Institute of Lymphology 1,000
Testing effectiveness (Phase 2)Study completedNCT01333748
What this trial is testing

Search Allelic Imbalance of Expression of BRCA Genes in Hereditary Risk of Breast and/or Ovarian Cancer

Who this might be right for
Hereditary Breast and Ovarian Cancer Syndrome
Centre Francois Baclesse 530
Not applicableLooking for participantsNCT07039552
What this trial is testing

Development and Validation of an Ovarian Cancer Risk Prediction Model for Family Members of Ovarian Cancer Probands

Who this might be right for
Hereditary Breast and Ovarian Cancer SyndromeBRCA Mutations
Peking University Third Hospital 10,000
Not applicableActive Not RecruitingNCT01230346
What this trial is testing

Culturally-Informed Counseling in Latinas at High Risk for Hereditary Breast or Ovarian Cancer

Who this might be right for
No Evidence of DiseaseBRCA1 SyndromeBRCA2 Syndrome+2 more
City of Hope Medical Center 493
Not applicableLooking for participantsNCT02775461
What this trial is testing

Pancreas Registry and High Risk Registry

Who this might be right for
Pancreas CancerPancreatitisChronic Pancreatitis+3 more
Icahn School of Medicine at Mount Sinai 1,368
Not applicableWithdrawnNCT02309632
What this trial is testing

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

Who this might be right for
Pancreatic NeoplasmsPeutz-Jegher's SyndromeBRCA1 Gene Mutation+5 more
University of Arkansas
Early research (Phase 1)Study completedNCT00535119
What this trial is testing

Veliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Cancer

Who this might be right for
Adult Solid NeoplasmBRCA1 Mutation CarrierBRCA2 Mutation Carrier+1 more
National Cancer Institute (NCI) 107
Not applicableActive Not RecruitingNCT04261972
What this trial is testing

Cell-free DNA in Hereditary And High-Risk Malignancies 1

Who this might be right for
Hereditary Cancer Syndrome
University Health Network, Toronto 1,416
Not applicableLooking for participantsNCT03805919
What this trial is testing

Men at High Genetic Risk for Prostate Cancer

Who this might be right for
Prostatic Neoplasms
National Cancer Institute (NCI) 500
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