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Results for “BTKi”

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Showing 20 of 0 results

Early research (Phase 1)Active Not RecruitingNCT04277637
What this trial is testing

Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies

Who this might be right for
Mature B-Cell Malignancies
BeOne Medicines 437
Testing effectiveness (Phase 2)Looking for participantsNCT07024706
What this trial is testing

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)
AstraZeneca 80
Testing effectiveness (Phase 2)WithdrawnNCT03370185
What this trial is testing

Phase 2 Study of Duvelisib in Previously Treated Patients With Chronic Lymphocytic Leukemia /Small Lymphocytic Lymphoma

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
SecuraBio
Large-scale testing (Phase 3)Looking for participantsNCT07342478
What this trial is testing

ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL

Who this might be right for
CLL / SLLCLL (Chronic Lymphocytic Leukemia)CLL, Refractory+5 more
Newave Pharmaceutical Inc 306
Large-scale testing (Phase 3)Active Not RecruitingNCT04002297
What this trial is testing

Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation

Who this might be right for
Mantle Cell Lymphoma; Non-Hodgkin Lymphoma
BeOne Medicines 510
Testing effectiveness (Phase 2)Looking for participantsNCT07271667
What this trial is testing

Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

Who this might be right for
Chronic Lymphocytic LeukemiaB-cell Malignancies
Curis, Inc. 108
Testing effectiveness (Phase 2)Looking for participantsNCT07520006
What this trial is testing

Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies

Who this might be right for
B-cell LymphomaChronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Nurix Therapeutics, Inc. 150
Large-scale testing (Phase 3)Active Not RecruitingNCT05023980
What this trial is testing

Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Loxo Oncology, Inc. 282
Testing effectiveness (Phase 2)Study completedNCT05432388
What this trial is testing

Study of Efficacy, Safety and Tolerability of Remibrutinib in Adult Participants With an Allergy to Peanuts

Who this might be right for
Allergy, Peanut
Novartis Pharmaceuticals 76
Early research (Phase 1)Ended earlyNCT04978779
What this trial is testing

Evaluate VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome

Who this might be right for
Relapsed Non Hodgkin LymphomaChronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic Leukemia+4 more
Vincerx Pharma, Inc. 6
Not applicableActive Not RecruitingNCT05999877
What this trial is testing

PICAROS - Acalabrutinib RWE on 1L CLL in Spain

Who this might be right for
Chronic Lymphocytic Leukemia
AstraZeneca 192
Not applicableApproved For MarketingNCT05172700
What this trial is testing

Expanded Access Program for Pirtobrutinib for Participants With B-Cell Cancer

Who this might be right for
Leukemia, Lymphocytic, Chronic, B-CellLymphoma, Lymphocytic, SmallLymphoma, Mantle-Cell+2 more
Loxo Oncology, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT07221500
What this trial is testing

NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)
Nurix Therapeutics, Inc. 100
Testing effectiveness (Phase 2)UnknownNCT05871684
What this trial is testing

A Combination Study of CAR-T Therapy in r/r B-NHL

Who this might be right for
Diffuse Large B Cell Lymphoma
Ruijin Hospital 48
Not applicableUnknownNCT06508684
What this trial is testing

Current Status of BTKi Treatment for CLL/SLL in China

Who this might be right for
CLL/SLL
The First Affiliated Hospital with Nanjing Medical University 1,000
Early research (Phase 1)Ended earlyNCT02292225
What this trial is testing

Duvelisib With Obinutuzumab in Patients With CLL/SLL Previously Treated With a BTKi (SYNCHRONY)

Who this might be right for
Lymphocytic Leukemia, ChronicLymphoma, Small Lymphocytic
SecuraBio 3
Testing effectiveness (Phase 2)Study completedNCT04116437
What this trial is testing

Zanubrutinib (BGB-3111) in Participants With Previously Treated B-Cell Lymphoma Intolerant of Prior Bruton Tyrosine Kinase Inhibitor (BTKi) Treatment

Who this might be right for
Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaMantle Cell LymphomaMarginal Zone Lymphoma+1 more
BeiGene 96
Not applicableStudy completedNCT05621148
What this trial is testing

REfractorinesS to Ibrutinib BTKi and Systemic Targeted Therapy

Who this might be right for
CLL, RelapsedCLL, RefractoryBruton Tyrosine Kinase Inhibitor+1 more
French Innovative Leukemia Organisation 152
Not applicableWithdrawnNCT05521178
What this trial is testing

Cardiotoxicities in Patients Receiving BTKi

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Dana-Farber Cancer Institute
Large-scale testing (Phase 3)Looking for participantsNCT07516093
What this trial is testing

Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL

Who this might be right for
B-cell LymphomaChronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Nurix Therapeutics, Inc. 620
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