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Results for “Becotatug Vedotin”

42 trials

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Showing 20 of 42 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07767266
What this trial is testing

Neoadjuvant Pucotenlimab and Becotatug Vedotin for Locally Advanced Penile Cancer

Who this might be right for
Penile CancerPenile Squamous Cell Carcinoma (PSCC)
Sun Yat-sen University 29
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07677475
What this trial is testing

MRG003 Plus Toripalimab Versus Toripalimab as Neoadjuvant Therapy for PD-L1-Positive, Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Dongguan People's Hospital 65
Testing effectiveness (Phase 2)Looking for participantsNCT07381075
What this trial is testing

A Phase II Clinical Trial of Anti-EGFR Antibody-drug Conjugate (ADC) Combined With or Without Immune Checkpoint Inhibitors in the Neoadjuvant Treatment of Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
West China Hospital 90
Early research (Phase 1)Not Yet RecruitingNCT07697040
What this trial is testing

Becotatug Vedotin Plus Cisplatin and Radiotherapy in LA-ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma
Hebei Medical University Fourth Hospital 12
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07766889
What this trial is testing

Neoadjuvant Presurgical Becotatug Vedotin (MRG003) Plus Pucotenlimab (HX008) in Oral Cavity Squamous Cell Carcinoma

Who this might be right for
Oral Squamous Cell CarcinomaHead and Neck CancerLocally Advanced Head and Neck Cancer+1 more
Sun Yat-sen University 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07545083
What this trial is testing

Neoadjuvant Becotatug Vedotin Plus Pucotenlimab in Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma (OSCC)

Who this might be right for
Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma
Shanghai Zhongshan Hospital 26
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07303283
What this trial is testing

Becotatug Vedotin as Adjuvant Therapy For High-risk Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Carcinoma (NPC)Locoregionally Advanced Nasopharyngeal CarcinomaAdjuvant Therapy
Kai Hu 140
Large-scale testing (Phase 3)Looking for participantsNCT07524452
What this trial is testing

Becotatug Vedotin (MRG003) in Combination With PD-1 Inhibitor Versus PD-1 Inhibitor for the Treatment of EGFR-positive, CPS≥1 Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Head and Neck Squamous Cell Carcinoma
Ming-Yuan Chen 430
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07394244
What this trial is testing

Pucotenlimab Combined With Becotatug Vedotin in Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma (CSCC)
Fudan University 38
Testing effectiveness (Phase 2)Looking for participantsNCT07403136
What this trial is testing

Becotatug Vedotin ± Anti-PD-1 in Pretreated Advanced ESCC

Who this might be right for
Esophageal Squamous Cell Carcinoma
Fudan University 104
Testing effectiveness (Phase 2)Looking for participantsNCT07522879
What this trial is testing

Becotatug Vedotin (MRG003) Combined With Epirubicin as Neoadjuvant Therapy for EGFR-Positive, Unresectable Recurrent Sinonasal Adenoid Cystic Carcinoma

Who this might be right for
Adenoid Cystic CarcinomaSinonasal Carcinoma
Eye & ENT Hospital of Fudan University 40
Large-scale testing (Phase 3)Looking for participantsNCT07459296
What this trial is testing

Becotatug Vedotin Plus Sintilimab in Locoregionally Advanced NPC

Who this might be right for
Nasopharyngeal Carcinoma (NPC)
First Affiliated Hospital of Guangxi Medical University 266
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07628855
What this trial is testing

A Prospective, Single-arm, Phase II Clinical Trial of Becotatug Vedotin for Injection Combined With Pucotenlimab Injection as a First-line Treatment for Platinum-intolerant Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
HNPCC
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07589049
What this trial is testing

Becotatug Vedotin Combined With Pucotenlimab as Neoadjuvant Therapy for Resectable Recurrent Head and Neck Squamous Cell Carcinoma After Progression on Immunotherapy: A Prospective Phase II Study

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Sun Yat-sen University 42
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07649980
What this trial is testing

Becotatug Vedotin Plus Pucotenlimab for Advanced Biliary Tract Cancer, Phase II

Who this might be right for
Biliary Tract Cancer (BTC)EGFR-positive Advanced Biliary Tract Carcinoma
HuiKai Li 30
Testing effectiveness (Phase 2)Looking for participantsNCT07536789
What this trial is testing

Becotatug Vedotin (MRG003) in Previously Treated Advanced Hepatocellular Carcinoma

Who this might be right for
Hepato Cellular Carcinoma (HCC)
Fudan University 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07800000
What this trial is testing

Becotatug Vedotin Plus Pucotenlimab and Capecitabine Followed by Concurrent Chemoradiotherapy-Immunotherapy for Locally Advanced Squamous Cell Carcinoma of the Anal Canal

Who this might be right for
Squamous Cell Carcinoma of the Anal Canal
Wang Xin 34
Testing effectiveness (Phase 2)Looking for participantsNCT07814287
What this trial is testing

Becotatug Vedotin Plus Pucotenlimab and Platinum Chemotherapy in Locally Advanced Epidermal Growth Factor Receptor (EGFR)-Positive Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma, HNSCC
Xuekui Liu 40
Early research (Phase 1)Looking for participantsNCT07584499
What this trial is testing

Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)Nasopharyngeal CarcinomaLymphoepithelial Carcinoma+7 more
Sun Yat-sen University 51
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07555860
What this trial is testing

Becotatug Vedotin Plus PD-1 Monoclonal Antibody and Radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Carcinoma
Sun Yat-sen University 28
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