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Results for “Beta Thalassemia-Major”

352 trials

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Showing 20 of 352 results

Not applicableActive Not RecruitingNCT05860595
What this trial is testing

Evaluation the Safety and Efficacy of KL003 Cell Injection in the Treatment of Transfusion-dependent β-thalassemia.

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Institute of Hematology & Blood Diseases Hospital, China 3
Early research (Phase 1)Study completedNCT02712346
What this trial is testing

The Role of Endothelin-1 in Sickle Cell Disease

Who this might be right for
Sickle Cell Anemia
Augusta University 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT06490601
What this trial is testing

Long Term Beta Thalassemia Treatment: Findings From The Extension Period

Who this might be right for
Fetal HemoglobinBeta-ThalassemiaHemoglobinopathies
National Institute of Blood and Marrow Transplant (NIBMT), Pakistan 30
Testing effectiveness (Phase 2)Looking for participantsNCT05735717
What this trial is testing

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Who this might be right for
Hematologic MalignancyAcute LeukemiaRemission+21 more
Masonic Cancer Center, University of Minnesota 70
Not applicableUnknownNCT05105659
What this trial is testing

Assessment of Cognitive Functions, Psychological Symptoms, and Quality of Life Among B Thalassemia Patients and Their Clinical Correlates.

Who this might be right for
B Thalassemia
Assiut University 60
Testing effectiveness (Phase 2)Study completedNCT01749540
What this trial is testing

Study to Evaluate the Safety and Efficacy of Luspatercept (ACE-536) in Participants With Beta-thalassemia (A536-04/MK-6143-002)

Who this might be right for
B-Thalassemia
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA 64
Early research (Phase 1)Looking for participantsNCT06647979
What this trial is testing

Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)Beta-Thalassemia+1 more
Daniel Bauer 10
Not applicableUnknownNCT04962984
What this trial is testing

Thrombin Generation in Beta-thalassemia Major

Who this might be right for
Beta Thalassemia Major Anemia
Central Hospital, Nancy, France 45
Not applicableNot Yet RecruitingNCT07614217
What this trial is testing

Oral Health Status in Children With β-Thalassemia Major

Who this might be right for
B Thalassemia Major
Cairo University 45
Testing effectiveness (Phase 2)UnknownNCT03183375
What this trial is testing

The Efficacy and Safety of HYDROXYUREA in Management of Beta Thalassemia Patients in Karachi Pakistan

Who this might be right for
Thalassemia, Beta
Dr.Saqib Hussain Ansari 100
Not applicableStudy completedNCT05529550
What this trial is testing

Assessment of Nutritional Status and Role of Insulin-like Growth Factor-1 in Children

Who this might be right for
Thalassemia
Menoufia University 102
Testing effectiveness (Phase 2)Ended earlyNCT01571635
What this trial is testing

Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.

Who this might be right for
Beta Thalassemia MajorBeta Thalassemia Intermedia
Celgene 46
Testing effectiveness (Phase 2)Looking for participantsNCT04143724
What this trial is testing

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

Who this might be right for
Beta-Thalassemia
Celgene 99
Not applicableStudy completedNCT04691323
What this trial is testing

The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD.

Who this might be right for
Sickle Cell DiseaseSickle B+ ThalassemiaSickle Beta Zero Thalassemia+1 more
Ann & Robert H Lurie Children's Hospital of Chicago 68
Not applicableUnknownNCT05133388
What this trial is testing

The Prevelence of HBB c.93-21 G-A in β Thalassemia Patients

Who this might be right for
Beta-Thalassemia
Assiut University 150
Not applicableStudy completedNCT04675645
What this trial is testing

Adherence to HU and HRQOL in Patients With Sickle Cell Disease: An Intervention Study Using HU-Go App

Who this might be right for
Sickle Cell DiseaseSickle B+ ThalassemiaSickle Beta Zero Thalassemia+1 more
Ann & Robert H Lurie Children's Hospital of Chicago 33
Not applicableActive Not RecruitingNCT06875219
What this trial is testing

To Evaluate Long- Term Safety and Efficacy of Luspatercept

Who this might be right for
Thalassemia Major
Fondazione per la Ricerca sulle Anemie ed Emoglobinopatie in Italia 350
Very early researchEnrolling By InvitationNCT06328764
What this trial is testing

CS-101 in Patients With β-thalassemia

Who this might be right for
Beta-Thalassemia
CorrectSequence Therapeutics Co., Ltd 10
Testing effectiveness (Phase 2)Study completedNCT07292259
What this trial is testing

Combination of Thalidomide and Hydroxyuria in Transfusion Dependent Thalasemmia

Who this might be right for
Transfusion Dependent Beta Thalassemia
Pakistan Blood and Marrow Transplant (PBMT) Group 100
Not applicableLooking for participantsNCT06734520
What this trial is testing

Clinical Study of Super Transplantation in the Treatment of Severe β-thalassemia

Who this might be right for
Thalassemia Majors (Beta-Thalassemia Major)Haplo-identical Donors
Guangzhou Women and Children's Medical Center 3
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