Not applicableStudy completedNCT02258997What this trial is testingHepcidin Levels in Sickle Cell Disease (SCD)Who this might be right forSickle Cell AnemiaSickle - Beta Thalassemia Kenneth Ataga, MD 42
Testing effectiveness (Phase 2)Looking for participantsNCT07599176What this trial is testingPartial Stem Cell Transplant for Sickle Cell Disease From Matched DonorsWho this might be right forSickle Cell DiseaseBeta-thalassemia National Heart, Lung, and Blood Institute (NHLBI) 90
Not applicableStudy completedNCT03764813What this trial is testingCord Blood Transfusion In Preterm Neonates (CB-TrIP)Who this might be right forPremature Infant DiseaseTransfusion Related ComplicationFetal Hemoglobin Fondazione Policlinico Universitario Agostino Gemelli IRCCS 25
Testing effectiveness (Phase 2)Study completedNCT00390858What this trial is testingA 4-year Extension Study to Core 1-year Study of Iron Chelation Therapy With Deferasirox in β-thalassemia Major Pediatric Patients With Transfusional Iron Overload.Who this might be right forTransfusional Iron Overloadβ-thalassemia MajorPediatric Rare Anemia Novartis Pharmaceuticals 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT05567458What this trial is testingEvaluate Luspatercept (ACE-536) in Chinese Participants Who Require Regular Red Blood Cell Transfusions Due to Beta (β)-Thalassemia.Who this might be right forBeta-thalassemia Bristol-Myers Squibb 94
Early research (Phase 1)Ended earlyNCT07431398What this trial is testingSingle-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Fulcrum Therapeutics 13
Testing effectiveness (Phase 2)Looking for participantsNCT06364774What this trial is testingALS20-101 Lentiviral Gene Therapy for Beta ThalassemiaWho this might be right forBeta-Thalassemia Children's Hospital of Philadelphia 12
Not applicableLooking for participantsNCT07112703What this trial is testingEffect of Incentive Respiratory Training on Pulmonary Functions and Functional Capacity in Children With B-thalassemia MajorWho this might be right forIncentive SpirometerPulmonary FunctionFunctional Capacity+2 more Rawan Mohammed Khairy Mostafa Elsawy 50
Early research (Phase 1)Looking for participantsNCT01245179What this trial is testingStudy of Panobinostat (LBH589) in Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Abdullah Kutlar 18
Not applicableUnknownNCT04962984What this trial is testingThrombin Generation in Beta-thalassemia MajorWho this might be right forBeta Thalassemia Major Anemia Central Hospital, Nancy, France 45
Not applicableUnknownNCT03868306What this trial is testingRed Cell Distribution Width Index Versus Red Cell Distribution Width as Discriminating Guide for Iron Deficiency Anaemia and Beta Thalassemia Trait .Who this might be right forMicrocytic Hypochromic Anemia Assiut University 100
Not applicableLooking for participantsNCT05773729What this trial is testingSafety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemiaWho this might be right forβ-thalassemia Shanghai BDgene Co., Ltd. 10
Large-scale testing (Phase 3)Study completedNCT01740531What this trial is testingStudy to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC TransfusionWho this might be right forThalassemia Major Cerus Corporation 86
Not applicableLooking for participantsNCT06314529What this trial is testingLong-term Follow-up Study of BHC001 for TDTWho this might be right forThalassemia, Beta Bioray Laboratories 6
Very early researchNot Yet RecruitingNCT06678165What this trial is testingA Pilot Study on the Safety and Efficacy of YOLT-204 for Transfusion-Dependent Beta-ThalassemiaWho this might be right forTransfusion Dependent Beta Thalassemia First Affiliated Hospital of Guangxi Medical University 3
Testing effectiveness (Phase 2)Looking for participantsNCT06490627What this trial is testingUnraveling the Impact of Thalidomide at Diverse Doses in Transfusion Dependent Beta ThalassemiaWho this might be right forFetal HemoglobinThalassemia MajorGenetic Disease National Institute of Blood and Marrow Transplant (NIBMT), Pakistan 54
Not applicableStudy completedNCT05687474What this trial is testingBaby Detect : Genomic Newborn ScreeningWho this might be right forCongenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07721480What this trial is testingGene Therapy for Patients With Transfusion-Dependent β-ThalassemiaWho this might be right forBeta Thalassemia Transfusion Dependent Prince of Wales Hospital, Shatin, Hong Kong 6
Post-approval studies (Phase 4)Study completedNCT06606886What this trial is testingEffects of Hydroxyurea and Metformin in Transfusion Dependent Beta-ThalassemiaWho this might be right forTransfusion Dependent Beta-thalassemia Bahria University 96
Testing effectiveness (Phase 2)Study completedNCT01709032What this trial is testingCombination Deferasirox and Deferiprone for Severe Iron Overload in ThalassemiaWho this might be right forThalassemia Major With Severe Transfusional Iron Overload Children's Hospital of Philadelphia 9