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Results for “Biologic; Inadequate”

58 trials

Showing 20 of 58 results

Large-scale testing (Phase 3)Ended earlyNCT03970837
What this trial is testing

Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic (cs)/Biologic (b) Disease Modifying Anti-rheumatic Drugs (DMARDs)

Who this might be right for
Arthritis, Rheumatoid
GlaxoSmithKline 1,764
Testing effectiveness (Phase 2)Study completedNCT00221000
What this trial is testing

Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Mallinckrodt 86
Large-scale testing (Phase 3)Active Not RecruitingNCT06276998
What this trial is testing

LNK01001 Capsule in Subjects With Active Rheumatoid Arthritis (COURAGE-RA)

Who this might be right for
Rheumatoid Arthritis
Lynk Pharmaceuticals Co., Ltd 430
Large-scale testing (Phase 3)WithdrawnNCT04483687
What this trial is testing

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Have an Inadequate Response to Biologic Disease-Modifying Antirheumatic Drug Therapy

Who this might be right for
Ankylosing Spondylitis
Gilead Sciences
Large-scale testing (Phase 3)Active Not RecruitingNCT06020144
What this trial is testing

Study Comparing TLL-018 to Tofacitinib in RA Subjects With Inadequate Response or Intolerance to bDMARDs

Who this might be right for
Rheumatoid Arthritis
Hangzhou Highlightll Pharmaceutical Co., Ltd 459
Large-scale testing (Phase 3)Study completedNCT03104400
What this trial is testing

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD)

Who this might be right for
Psoriatic Arthritis
AbbVie 1,705
Large-scale testing (Phase 3)Study completedNCT02706847
What this trial is testing

Compare Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) With an Inadequate Response or Intolerance to Biologic DMARDs

Who this might be right for
Rheumatoid Arthritis
AbbVie 499
Post-approval studies (Phase 4)Study completedNCT01195272
What this trial is testing

The Effects of RoActemra/Actemra (Tocilizumab) on Neutrophils in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic and/or Non-biologic DMARDs.

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 21
Large-scale testing (Phase 3)Study completedNCT01091675
What this trial is testing

Assessment of the Response to Etoricoxib in Patients With Ankylosing Spondylitis and Inadequate Response to ≥2 NSAIDs

Who this might be right for
Ankylosing Spondylitis
Spanish Foundation of Rheumatology 58
Post-approval studies (Phase 4)Study completedNCT01059773
What this trial is testing

A Safety and Efficacy Study of Ustekinumab in Patients With Plaque Psoriasis Who Have Had an Inadequate Response to Methotrexate

Who this might be right for
Psoriasis
Janssen-Cilag International NV 490
Post-approval studies (Phase 4)Looking for participantsNCT05552287
What this trial is testing

Pharmacokinetic Infliximab Data in Pediatric Crohn's Disease

Who this might be right for
Crohn DiseaseChild, OnlyBiologic; Inadequate
Erasmus Medical Center 50
Large-scale testing (Phase 3)Study completedNCT02873936
What this trial is testing

Filgotinib Versus Placebo in Adults With Active Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Biologic Disease-modifying Anti-rheumatic Drug(s) (DMARDs) Treatment

Who this might be right for
Rheumatoid Arthritis
Gilead Sciences 449
Large-scale testing (Phase 3)Study completedNCT01987479
What this trial is testing

A Study on Safety and Efficacy of Tocilizumab (RoActemra/Actemra) Alone or in Combination With Non-Biologic Antirheumatics in Participants With Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 150
Testing effectiveness (Phase 2)Ended earlyNCT01636843
What this trial is testing

A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Methotrexate

Who this might be right for
InflammationRheumatoid Arthritis
Novo Nordisk A/S 298
Large-scale testing (Phase 3)Study completedNCT03086343
What this trial is testing

Compare Upadacitinib to Abatacept in Subjects With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease- Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response or Intolerance to Biologic DMARDs

Who this might be right for
Rheumatoid Arthritis (RA)
AbbVie 657
Large-scale testing (Phase 3)Study completedNCT03104374
What this trial is testing

A Study Comparing Upadacitinib (ABT-494) to Placebo in Participants With Active Psoriatic Arthritis Who Have a History of Inadequate Response to at Least One Biologic Disease Modifying Anti-Rheumatic Drug

Who this might be right for
Psoriatic Arthritis
AbbVie 642
Not applicableUnknownNCT04438642
What this trial is testing

Biological and Esthetic Evaluation of Ceramic Onlay With Different Preparation Designs

Who this might be right for
Unsatisfactory Restoration of ToothCarious Teeth
Ahmed Adel Mahmoud Gadallah 38
Large-scale testing (Phase 3)Study completedNCT01245439
What this trial is testing

RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 65
Large-scale testing (Phase 3)Study completedNCT01844518
What this trial is testing

Pharmacokinetics, Efficacy and Safety of Abatacept Administered Subcutaneously (SC) in Children and Adolescents With Active Polyarticular Juvenile Idiopathic Arthritis (pJIA) and Inadequate Response (IR) to Biologic or Non Biologic Disease Modifying Anti-rheumatic Drugs (DMARDs)

Who this might be right for
Active Polyarticular Juvenile Idiopathic Arthritis
Bristol-Myers Squibb 219
Not applicableStudy completedNCT01617005
What this trial is testing

Tocilizumab in Participants With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Non-Biological Disease-modifying Anti-rheumatic Drugs (DMARDs)

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 50
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