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Results for “Bispecific”

570 trials

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Showing 20 of 570 results

Large-scale testing (Phase 3)Looking for participantsNCT05549297
What this trial is testing

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

Who this might be right for
Advanced Melanoma
Immunocore Ltd 540
Early research (Phase 1)Study completedNCT00889408
What this trial is testing

DT2219ARL for Relapsed or Refractory CD19 (+), CD 22 (+) B-Lineage Leukemia Or Lymphoma

Who this might be right for
LeukemiaLymphoma
Masonic Cancer Center, University of Minnesota 25
Early research (Phase 1)Ended earlyNCT03927573
What this trial is testing

Study With Bispecific Antibody Engaging T-cells, in Patients With Progressive Cancer Diseases With Positive PSCA Marker

Who this might be right for
Non-small Cell Lung CancerProstate CancerRenal Cancer+1 more
AvenCell Europe GmbH 23
Early research (Phase 1)Active Not RecruitingNCT04606381
What this trial is testing

Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies

Who this might be right for
Neoplasms
Janssen Research & Development, LLC 158
Testing effectiveness (Phase 2)Study completedNCT01730612
What this trial is testing

ImmunoTEP au 68-Ga- IMP-288 for Patients With a Recurrence of HER2 Negative Breast Carcinoma Expressing CEA

Who this might be right for
HER2 Negative Breast Carcinoma Expressing CEA
Nantes University Hospital 23
Early research (Phase 1)Study completedNCT03915379
What this trial is testing

JNJ-67571244 in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Janssen Research & Development, LLC 68
Early research (Phase 1)Active Not RecruitingNCT05362773
What this trial is testing

MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

Who this might be right for
Leukemia, Acute MyeloidMyelodysplastic SyndromesClassical Hodgkin Lymphoma+5 more
MacroGenics 130
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06946836
What this trial is testing

Comparison of Neoadjuvant Cadonilimab Versus Chemotherapy Combined With PD-1 in the Treatment of Resectable Non-Small Cell Lung Cancer With High PD-L1 Expression: A Single-Center, Randomized, Exploratory Clinical Study

Who this might be right for
Resectable Non-small Cell Lung CancerBispecific AntibodyNeoadjuvant Therapy
Shanghai Pulmonary Hospital, Shanghai, China 80
Testing effectiveness (Phase 2)Looking for participantsNCT05125016
What this trial is testing

A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
Regeneron Pharmaceuticals 228
Testing effectiveness (Phase 2)Ended earlyNCT02243787
What this trial is testing

Safety and Tolerability Study of COVA322 in Patients With Stable Chronic Moderate-to-severe Plaque Psoriasis

Who this might be right for
Plaque Psoriasis
Covagen 24
Early research (Phase 1)Looking for participantsNCT07563829
What this trial is testing

NPX372, a B7-H7:CD3 Bispecific Antibody, in Selected Solid Tumor Malignancies

Who this might be right for
Metastatic Malignant Neoplasm
NextPoint Therapeutics, Inc. 81
Large-scale testing (Phase 3)Looking for participantsNCT06091865
What this trial is testing

Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large B-cell Lymphoma (DLBCL)
Regeneron Pharmaceuticals 904
Early research (Phase 1)Not Yet RecruitingNCT07335328
What this trial is testing

Fully Human Bispecific Anti-CD20, Anti-CD19 CAR T Cells for Patients With Relapsed and/or Refractory B Cell Malignancies

Who this might be right for
B-cell Non Hodgkin Lymphoma
Medical College of Wisconsin 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT04868877
What this trial is testing

Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination

Who this might be right for
Non-Small Cell Lung Cancer MetastaticGastric CancerEsophageal Squamous Cell Carcinoma+2 more
Merus B.V. 194
Testing effectiveness (Phase 2)Looking for participantsNCT06367075
What this trial is testing

A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma

Who this might be right for
Advanced Soft-tissue Sarcoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 53
Testing effectiveness (Phase 2)Looking for participantsNCT06540729
What this trial is testing

RC48 in Combination With AK104 and Bevacizumab in OCCC

Who this might be right for
Ovary Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 39
Testing effectiveness (Phase 2)Looking for participantsNCT07049055
What this trial is testing

A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer

Who this might be right for
Pancreatic Cancer, MetastaticPDAC - Pancreatic Ductal Adenocarcinoma
Engeneic Pty Limited 144
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07115654
What this trial is testing

BCMA/CD3 BsAb Therapy for POEMS Syndrome

Who this might be right for
POEMS Syndrome
Institute of Hematology & Blood Diseases Hospital, China 10
Early research (Phase 1)Study completedNCT02748837
What this trial is testing

ERY974 in Patient With Advanced Solid Tumors

Who this might be right for
Solid Tumors
Chugai Pharmaceutical 29
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06885840
What this trial is testing

Study of MCLA-129 in the Treatment of Advanced Non-small Cell Lung Cancer with AGA and MET Amplification.

Who this might be right for
Non-Small Cell Lung Cancer
Betta Pharmaceuticals Co., Ltd. 100
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