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Results for “Bispecific”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT03515551
What this trial is testing

Safety and Efficacy of IMCnyeso in Advanced NY-ESO-1 and/or LAGE-1A Positive Cancers

Who this might be right for
Select Advanced Solid Tumors
Immunocore Ltd 29
Testing effectiveness (Phase 2)Looking for participantsNCT06809517
What this trial is testing

Intrathecal PD-1/VEGF Bispecific Antibody Plus Pemetrexed for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisIntrathecal Drug Delivery
Guangzhou Medical University 34
Testing effectiveness (Phase 2)Looking for participantsNCT07455851
What this trial is testing

A Trial to Study if REGN17372 in Combination With Linvoseltamab is Tolerable for Adult Participants With Relapsed/Refractory Multiple Myeloma

Who this might be right for
Relapsed Refractory Multiple Myeloma (RRMM)
Regeneron Pharmaceuticals 150
Testing effectiveness (Phase 2)Looking for participantsNCT04777084
What this trial is testing

The Efficacy and Safety of the Bispecific Anti-PD-1/PD-L1 Antibody IBI318 Combined with Lenvatinib in NSCLC.

Who this might be right for
Non-Small Cell Lung Cancer
Hunan Province Tumor Hospital 120
Testing effectiveness (Phase 2)Study completedNCT03321981
What this trial is testing

MCLA-128 With Trastuzumab/Chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer.

Who this might be right for
Breast Cancer Metastatic
Merus B.V. 105
Testing effectiveness (Phase 2)Looking for participantsNCT04930432
What this trial is testing

Study of MCLA-129, a Human Bispecific EGFR and cMet Antibody, in Patients With Advanced NSCLC and Other Solid Tumors

Who this might be right for
Solid TumorNon-Small Cell Lung CancerHead and Neck Cancer+1 more
Betta Pharmaceuticals Co., Ltd. 400
Testing effectiveness (Phase 2)Active Not RecruitingNCT06035224
What this trial is testing

Cadonilimab (AK104) Plus Lenvatinib in Previously Immunotherapy-Treated Advanced/Metastatic Clear Cell Renal Cell Carcinoma

Who this might be right for
Clear Cell Renal Cell Carcinoma
RenJi Hospital 28
Early research (Phase 1)Not Yet RecruitingNCT07583316
What this trial is testing

First-in-Human Study of CRPA1A2, a MAGE-A1/HLA-A*02:01 Bispecific T-Cell Engager, in Patients With Solid Tumors

Who this might be right for
Lung Cancer (Locally Advanced or Metastatic)Esophagus CancerHead and Neck Cancer+1 more
Corregene Biotechnology Co., Ltd 192
Early research (Phase 1)Not Yet RecruitingNCT07744243
What this trial is testing

SI-B036 in Patients With Locally Advanced or Metastatic Urological Tumors and Other Solid Tumors

Who this might be right for
Urological CancerSolid Cancer
Sichuan Baili Pharmaceutical Co., Ltd. 30
Testing effectiveness (Phase 2)Looking for participantsNCT07147348
What this trial is testing

A First-in-human, Dose Escalation and Indication Expansion Study of BNT3212 as Monotherapy or in Combination With BNT327 in Adults With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 375
Early research (Phase 1)Study completedNCT04572152
What this trial is testing

AK119 (Anti-CD73) in Combination With AK104 in Subjects With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Akeso 23
Testing effectiveness (Phase 2)Looking for participantsNCT07623525
What this trial is testing

DIAG723 in Adults With Hereditary Hemorrhagic Telangiectasia

Who this might be right for
Hereditary Hemorrhagic TelangiectasiaPulmonary Arterial Hypertension
Diagonal Therapeutics, Inc. 93
Testing effectiveness (Phase 2)WithdrawnNCT04841538
What this trial is testing

ES101 (PD-L1x4-1BB Bispecific Antibody) in Patients With Advanced Malignant Thoracic Tumors

Who this might be right for
Thoracic TumorsNon-small Cell Lung CancerSmall Cell Lung Cancer
Elpiscience Biopharma, Ltd.
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07086326
What this trial is testing

A Phase II Randomized Trial of Neoadjuvant Ivonescimab or Penpulimab Plus Chemotherapy in Resectable NSCLC

Who this might be right for
NSCLCNeoadjuvant TherapyImmunotherapy+2 more
Yang Fan, MD 164
Early research (Phase 1)Looking for participantsNCT06975787
What this trial is testing

Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis

Who this might be right for
Lupus Nephritis (LN)
Regeneron Pharmaceuticals 90
Testing effectiveness (Phase 2)Active Not RecruitingNCT05798156
What this trial is testing

Rituximab in Combination With Glofitamab and Polatuzumab Vedotin in Patients With Previously Untreated Aggressive B-cell Lymphoma Ineligible for R-CHOP

Who this might be right for
Lymphoma, Large B-Cell, Diffuse
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 125
Testing effectiveness (Phase 2)WithdrawnNCT04864522
What this trial is testing

Phase I/II Study of SLAMF7 FPBMC/CS-1 FPBMC in Relapsed/Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
University of Virginia
Testing effectiveness (Phase 2)Looking for participantsNCT07680764
What this trial is testing

Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Locally Advanced Non-Small Cell Lung Cancer (NSCLC)Metastatic Non-Small Cell Lung Cancer (NSCLC)
Bristol-Myers Squibb 160
Early research (Phase 1)Not Yet RecruitingNCT05940116
What this trial is testing

A Phase I Clinical Study of HS-20117 in Participants With Advanced Solid Tumors

Who this might be right for
Non-Small Cell Lung CancerSolid Tumor
Hansoh BioMedical R&D Company 322
Testing effectiveness (Phase 2)Study completedNCT04083534
What this trial is testing

First In Human (FIH) Study of REGN5459 in Adult Patients With Relapsed or Refractory Multiple Myeloma (MM)

Who this might be right for
Relapsed Multiple MyelomaRefractory Multiple Myeloma
Regeneron Pharmaceuticals 43
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