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Results for “Bispecific Antibodies”

467 trials

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Showing 20 of 467 results

Early research (Phase 1)Ended earlyNCT03927573
What this trial is testing

Study With Bispecific Antibody Engaging T-cells, in Patients With Progressive Cancer Diseases With Positive PSCA Marker

Who this might be right for
Non-small Cell Lung CancerProstate CancerRenal Cancer+1 more
AvenCell Europe GmbH 23
Early research (Phase 1)Active Not RecruitingNCT04606381
What this trial is testing

Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies

Who this might be right for
Neoplasms
Janssen Research & Development, LLC 158
Testing effectiveness (Phase 2)Study completedNCT01730612
What this trial is testing

ImmunoTEP au 68-Ga- IMP-288 for Patients With a Recurrence of HER2 Negative Breast Carcinoma Expressing CEA

Who this might be right for
HER2 Negative Breast Carcinoma Expressing CEA
Nantes University Hospital 23
Early research (Phase 1)Study completedNCT03915379
What this trial is testing

JNJ-67571244 in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Janssen Research & Development, LLC 68
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06946836
What this trial is testing

Comparison of Neoadjuvant Cadonilimab Versus Chemotherapy Combined With PD-1 in the Treatment of Resectable Non-Small Cell Lung Cancer With High PD-L1 Expression: A Single-Center, Randomized, Exploratory Clinical Study

Who this might be right for
Resectable Non-small Cell Lung CancerBispecific AntibodyNeoadjuvant Therapy
Shanghai Pulmonary Hospital, Shanghai, China 80
Testing effectiveness (Phase 2)Looking for participantsNCT05125016
What this trial is testing

A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
Regeneron Pharmaceuticals 228
Testing effectiveness (Phase 2)Ended earlyNCT02243787
What this trial is testing

Safety and Tolerability Study of COVA322 in Patients With Stable Chronic Moderate-to-severe Plaque Psoriasis

Who this might be right for
Plaque Psoriasis
Covagen 24
Early research (Phase 1)Looking for participantsNCT07563829
What this trial is testing

NPX372, a B7-H7:CD3 Bispecific Antibody, in Selected Solid Tumor Malignancies

Who this might be right for
Metastatic Malignant Neoplasm
NextPoint Therapeutics, Inc. 81
Large-scale testing (Phase 3)Looking for participantsNCT06091865
What this trial is testing

Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large B-cell Lymphoma (DLBCL)
Regeneron Pharmaceuticals 904
Testing effectiveness (Phase 2)Active Not RecruitingNCT04868877
What this trial is testing

Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination

Who this might be right for
Non-Small Cell Lung Cancer MetastaticGastric CancerEsophageal Squamous Cell Carcinoma+2 more
Merus B.V. 194
Testing effectiveness (Phase 2)Looking for participantsNCT06367075
What this trial is testing

A Trial of Cadonilimab With Adriamycin in Patients With Advanced Soft Tissue Sarcoma

Who this might be right for
Advanced Soft-tissue Sarcoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 53
Testing effectiveness (Phase 2)Looking for participantsNCT07049055
What this trial is testing

A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer

Who this might be right for
Pancreatic Cancer, MetastaticPDAC - Pancreatic Ductal Adenocarcinoma
Engeneic Pty Limited 144
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07115654
What this trial is testing

BCMA/CD3 BsAb Therapy for POEMS Syndrome

Who this might be right for
POEMS Syndrome
Institute of Hematology & Blood Diseases Hospital, China 10
Early research (Phase 1)Study completedNCT02748837
What this trial is testing

ERY974 in Patient With Advanced Solid Tumors

Who this might be right for
Solid Tumors
Chugai Pharmaceutical 29
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06885840
What this trial is testing

Study of MCLA-129 in the Treatment of Advanced Non-small Cell Lung Cancer with AGA and MET Amplification.

Who this might be right for
Non-Small Cell Lung Cancer
Betta Pharmaceuticals Co., Ltd. 100
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06416930
What this trial is testing

Study of Cadonilimab Combined With Chemotherapy in Recurrent / Refractory Pleural Mesothelioma

Who this might be right for
Pleural Mesothelioma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 59
Testing effectiveness (Phase 2)Looking for participantsNCT07070232
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 1,438
Large-scale testing (Phase 3)Looking for participantsNCT07222761
What this trial is testing

Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Who this might be right for
Relapsed and/or Refractory Multiple Myeloma (RRMM)
Regeneron Pharmaceuticals 915
Testing effectiveness (Phase 2)Study completedNCT04900363
What this trial is testing

A Trial of AK112 (PD-1/VEGF Bispecific Antibody) in Patients With NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Akeso 108
Testing effectiveness (Phase 2)Study completedNCT04380805
What this trial is testing

AK104, a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer

Who this might be right for
Recurrent Cervical CancerMetastatic Cervical Cancer
Akeso 30
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