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Results for “Bispecific Antibody”

469 trials

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Showing 20 of 469 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07644208
What this trial is testing

PD-1/IL-2 Bispecific Antibody as Neoadjuvant Therapy for Early Recurrent Hepatocellular Carcinoma After Curative Hepatectomy

Who this might be right for
Hepatocellular Carcinoma (HCC)
Shanghai Zhongshan Hospital 30
Early research (Phase 1)WithdrawnNCT05381935
What this trial is testing

ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
Elpiscience Biopharma, Ltd.
Large-scale testing (Phase 3)Looking for participantsNCT06006117
What this trial is testing

Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone Lymphoma

Who this might be right for
Marginal Zone Lymphoma
The Lymphoma Academic Research Organisation 260
Early research (Phase 1)Study completedNCT05011097
What this trial is testing

A Phase I Clinical Trial of Y150 in the Treatment of Relapsed or Refractory Multiple Myeloma

Who this might be right for
Relapsed or Refractory Multiple Myeloma
Wuhan YZY Biopharma Co., Ltd. 20
Early research (Phase 1)Temporarily pausedNCT05076591
What this trial is testing

IMM2902, a HER2/SIRPα Bispecific MAb-Trap Antibody-receptor Fusion Protein, in Patients with HER2-expressing Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorAdvanced Breast CancerAdvanced Gastric Cancer
ImmuneOnco Biopharmaceuticals (Shanghai) Inc. 135
Testing effectiveness (Phase 2)Ended earlyNCT05159388
What this trial is testing

PRS-344/S095012 (PD-L1x4-1BB Bispecific Antibody) in Patients With Solid Tumors

Who this might be right for
Solid Tumor
Servier Bio-Innovation LLC 46
Large-scale testing (Phase 3)Looking for participantsNCT06091254
What this trial is testing

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma

Who this might be right for
Follicular Lymphoma (FL)
Regeneron Pharmaceuticals 822
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06586294
What this trial is testing

Anti-PD-1 and LAG-3 Bispecific Antibody(AK129) Combined With Chemotherapy With or Without Cadonilimab in the First-line Treatment of Unresectable Locally Advanced or Metastatic G/ GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Akeso 294
Large-scale testing (Phase 3)Not Yet RecruitingNCT07740486
What this trial is testing

A Study Comparing Treatment With Teclistamab and Talquetamab Versus Daratumumab and Lenalidomide in Patients With Multiple Myeloma After Stem Cell Transplant Who Still Have Detectable Disease

Who this might be right for
Multiple Myeloma (MM)
Polish Myeloma Consortium 248
Testing effectiveness (Phase 2)Study completedNCT04083534
What this trial is testing

First In Human (FIH) Study of REGN5459 in Adult Patients With Relapsed or Refractory Multiple Myeloma (MM)

Who this might be right for
Relapsed Multiple MyelomaRefractory Multiple Myeloma
Regeneron Pharmaceuticals 43
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07449156
What this trial is testing

Evaluate Efficacy and Safety of HB0043 in Aadult Patients With Moderate to Severe Acne Vulgaris.

Who this might be right for
Acne Vulgaris
Shanghai Huaota Biopharmaceutical Co., Ltd. 21
Early research (Phase 1)Active Not RecruitingNCT04108195
What this trial is testing

Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma

Who this might be right for
Multiple Myeloma
Janssen Research & Development, LLC 290
Testing effectiveness (Phase 2)Looking for participantsNCT07432022
What this trial is testing

A Phase I/II Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of the EMB-07 Combination Therapy in Patients With Aggressive B-Cell Non-Hodgkin Lymphoma

Who this might be right for
Combination TherapyAggressive B-Cell Non-Hodgkin LymphomaEMB07+1 more
Shanghai EpimAb Biotherapeutics Co., Ltd. 115
Testing effectiveness (Phase 2)Looking for participantsNCT07014319
What this trial is testing

Phase II Trial of Maribavir for CMV in Patients With Lymphoid Malignancy on Bispecific Antibodies

Who this might be right for
Cytomegalovirus (CMV)
Seoul National University Hospital 20
Large-scale testing (Phase 3)Looking for participantsNCT07258511
What this trial is testing

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Janssen Research & Development, LLC 400
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06946836
What this trial is testing

Comparison of Neoadjuvant Cadonilimab Versus Chemotherapy Combined With PD-1 in the Treatment of Resectable Non-Small Cell Lung Cancer With High PD-L1 Expression: A Single-Center, Randomized, Exploratory Clinical Study

Who this might be right for
Resectable Non-small Cell Lung CancerBispecific AntibodyNeoadjuvant Therapy
Shanghai Pulmonary Hospital, Shanghai, China 80
Testing effectiveness (Phase 2)Study completedNCT00464893
What this trial is testing

Phase II Study With Catumaxomab in Patients With Gastric Cancer After Neoadjuvant CTx and Curative Resection

Who this might be right for
Gastric CancerGastric Adenocarcinoma
Neovii Biotech 70
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06837948
What this trial is testing

Neoadjuvant Chemotherapy Combined With Bispecific Antibody Versus Monoclonal Antibody in Locally Advanced NSCLC

Who this might be right for
Locally Advanced Non-Small Cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China 160
Early research (Phase 1)Looking for participantsNCT06826768
What this trial is testing

A Ph Ib Study of REGN5678 Plus Cemiplimab in Patients With mCRPC

Who this might be right for
Prostate Cancer
M.D. Anderson Cancer Center 60
Early research (Phase 1)Not Yet RecruitingNCT07778862
What this trial is testing

SI-B036 in Patients With Locally Advanced or Metastatic Gynecological Tumors and Other Solid Tumors

Who this might be right for
Gynecological TumorsSolid Tumors
Sichuan Baili Pharmaceutical Co., Ltd. 30
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