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Results for “Bispecific Antibody”

404 trials

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Showing 20 of 404 results

Early research (Phase 1)Study completedNCT00938626
What this trial is testing

Treated T Cells Followed by a Stem Cell Transplant in Treating Patients With Multiple Myeloma

Who this might be right for
Multiple Myeloma and Plasma Cell Neoplasm
Barbara Ann Karmanos Cancer Institute 12
Early research (Phase 1)Ended earlyNCT04740034
What this trial is testing

AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate Carcinoma

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
Amgen 42
Testing effectiveness (Phase 2)Looking for participantsNCT06892548
What this trial is testing

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

Who this might be right for
Advanced Lung Cancer
BioNTech SE 594
Early research (Phase 1)Not Yet RecruitingNCT07234474
What this trial is testing

A Phase I Study of YK012 in Primary Membranous Nephropathy

Who this might be right for
Primary Membranous Nephropathy
Excyte Biopharma Ltd 66
Large-scale testing (Phase 3)Looking for participantsNCT06712355
What this trial is testing

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

Who this might be right for
Extensive-stage Small-cell Lung Cancer
BioNTech SE 621
Early research (Phase 1)Ended earlyNCT05077423
What this trial is testing

Trial of CD33xCD3 BsAb in Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
AML, Childhood
Y-mAbs Therapeutics 3
Early research (Phase 1)Looking for participantsNCT06803680
What this trial is testing

BGB-B455 in Adults With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
BeiGene 90
Large-scale testing (Phase 3)Looking for participantsNCT05730036
What this trial is testing

A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma

Who this might be right for
Relapsed Refractory Multiple Myeloma (RRMM)
Regeneron Pharmaceuticals 410
Early research (Phase 1)Looking for participantsNCT07161414
What this trial is testing

Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy

Who this might be right for
Advanced Solid Tumors
AstraZeneca 40
Testing effectiveness (Phase 2)UnknownNCT03797391
What this trial is testing

A Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors

Who this might be right for
NeoplasmsNeoplasm MetastasisNon-Small-Cell Lung Cancer
Shanghai EpimAb Biotherapeutics Co., Ltd. 186
Early research (Phase 1)Looking for participantsNCT06621563
What this trial is testing

Phase Ib Trial of HS-20117 in Combination With Other Drugs in Advanced Solid Tumors

Who this might be right for
Solid TumorsNon-Small Cell Lung CancerColorectal Cancer
Hansoh BioMedical R&D Company 780
Not applicableLooking for participantsNCT05106387
What this trial is testing

An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

Who this might be right for
Chronic Kidney Disease (CKD)
Regeneron Pharmaceuticals 20
Testing effectiveness (Phase 2)WithdrawnNCT03484962
What this trial is testing

Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Liver Cancer

Who this might be right for
Advanced Liver Cancer
Fuda Cancer Hospital, Guangzhou
Testing effectiveness (Phase 2)Study completedNCT01209286
What this trial is testing

Study of the BiTE® Blinatumomab (MT103) in Adult Patients With Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
B-ALL
Amgen Research (Munich) GmbH 36
Testing effectiveness (Phase 2)Looking for participantsNCT07208773
What this trial is testing

YL201 and Ivonescimab (AK112) in Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsNon Small Cell Lung CancerSmall Cell Lung Cancer
MediLink Therapeutics (Suzhou) Co., Ltd. 260
Large-scale testing (Phase 3)Looking for participantsNCT07221253
What this trial is testing

Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

Who this might be right for
Biliary Tract Cancer
AstraZeneca 1,100
Early research (Phase 1)Study completedNCT03340766
What this trial is testing

Study Investigating the Safety and Efficacy of Blinatumomab in Combination With Pembrolizumab in Adults With Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)

Who this might be right for
Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Amgen 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT04556253
What this trial is testing

AK104 in Locally Advanced MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer

Who this might be right for
MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer
Peking University 47
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06586294
What this trial is testing

Anti-PD-1 and LAG-3 Bispecific Antibody(AK129) Combined With Chemotherapy With or Without Cadonilimab in the First-line Treatment of Unresectable Locally Advanced or Metastatic G/ GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Akeso 294
Early research (Phase 1)Active Not RecruitingNCT04108195
What this trial is testing

Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma

Who this might be right for
Multiple Myeloma
Janssen Research & Development, LLC 290
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