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Results for “Blood Brain Barrier”

185 trials

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Showing 20 of 185 results

Testing effectiveness (Phase 2)Study completedNCT02819479
What this trial is testing

Low-dose Intra-arterial Bevacizumab for Edema and Radiation Necrosis Therapeutic Intervention (LIBERTI)

Who this might be right for
Radiation Necrosis
Norton Healthcare 10
Testing effectiveness (Phase 2)Study completedNCT04417088
What this trial is testing

Exablate Blood-Brain Barrier Disruption for the Treatment of rGBM in Subjects Undergoing Carboplatin Monotherapy

Who this might be right for
Recurrent Glioblastoma
InSightec 28
Post-approval studies (Phase 4)Looking for participantsNCT05780905
What this trial is testing

Effects of Semaglutide on Intracranial Blood Flow and Brain-Barrier Permeability in Type-2 Diabetes

Who this might be right for
Diabetes Mellitus, Type 2Stroke (CVA) or Transient Ischemic Attack
University of Washington 50
Not applicableUnknownNCT00258505
What this trial is testing

Monitoring Brain Activity in Human Brain Injury

Who this might be right for
Traumatic Brain InjuryAneurysmal Subarachnoid HemorrhageCerebral Infarction+1 more
Soroka University Medical Center 100
Testing effectiveness (Phase 2)UnknownNCT01830894
What this trial is testing

Feasibility Study of New MRI Protocol in Assessing Early Blood Brain Barrier Disruption (BBBD)in Related to Delay Brain Edema

Who this might be right for
Intra Cerebral Hemorrhage
Sheba Medical Center 30
Not applicableStudy completedNCT04370665
What this trial is testing

Blood-Brain-Barrier Disruption With Cerezyme in Patient's With Parkinson's Disease

Who this might be right for
Parkinson Disease
InSightec 4
Not applicableStudy completedNCT05820230
What this trial is testing

Changes in the Blood-brain Barrier During Maintenance ECT in Formerly Depressed Patients

Who this might be right for
Depression
University of Copenhagen 7
Large-scale testing (Phase 3)Study completedNCT03284463
What this trial is testing

Safety and Efficacy of Glibenclamide Combined With Rt-PA in Acute Cerebral Embolism

Who this might be right for
Acute Stroke
Nanfang Hospital, Southern Medical University 306
Testing effectiveness (Phase 2)Looking for participantsNCT05864534
What this trial is testing

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Who this might be right for
Newly Diagnosed GlioblastomaGlioblastoma, Isocitric Dehydrogenase (IDH)-WildtypeGliosarcoma+1 more
Northwestern University 25
Large-scale testing (Phase 3)Looking for participantsNCT06496971
What this trial is testing

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

Who this might be right for
Glioblastoma MultiformeGlioblastomaGlioblastoma Multiforme, Adult+5 more
NaviFUS Corporation 32
Testing effectiveness (Phase 2)Ended earlyNCT02372409
What this trial is testing

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Who this might be right for
GliomaPilocytic AstrocytomaAnaplastic Astrocytoma+6 more
Washington University School of Medicine 6
Early research (Phase 1)Temporarily pausedNCT04222309
What this trial is testing

Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)

Who this might be right for
GliomaGlioma, MalignantGlioblastoma+4 more
Northwell Health 10
Testing effectiveness (Phase 2)Study completedNCT01399905
What this trial is testing

High and Low Dose Carbidopa Treatment of Parkinson's Disease

Who this might be right for
Parkinson's Disease
Oregon Health and Science University 14
Not applicableTemporarily pausedNCT03322813
What this trial is testing

ExAblate Blood Brain Barrier Disruption (BBBD) for Planned Surgery in Suspected Infiltrating Glioma

Who this might be right for
Glioma
InSightec 15
Testing effectiveness (Phase 2)Looking for participantsNCT07485452
What this trial is testing

Boosting Osimertinib Blood Brain Barrier Penetration

Who this might be right for
Non-Small Cell Lung Cancer
Maastricht University Medical Center 7
Not applicableNot Yet RecruitingNCT07514949
What this trial is testing

The Feasibility and Safety of RK-4 Injection Bypassing Blood-brain Barrier in the Treatment of Acute Large Hemispheric Infarction Using Intracalvariosseous Injection Device

Who this might be right for
StrokeAcute Ischemic StrokeBlood-Brain Barrier
yilong Wang 6
Testing effectiveness (Phase 2)Looking for participantsNCT06818331
What this trial is testing

Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial

Who this might be right for
Glioma
The Third Affiliated hospital of Zhejiang Chinese Medical University 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07583147
What this trial is testing

Role of Neuroinflammation and Blood-Brain Barrier Breakdown in Intracerebral Hemorrhage.

Who this might be right for
Intracerebral Hemorrhage
University Hospital, Toulouse 117
Not applicableStudy completedNCT06353516
What this trial is testing

The Effect of Intravenous Versus Volatile Anesthesia on Postoperative Cognitive Dysfunction in Elderly Patients

Who this might be right for
Postoperative Cognitive Dysfunction
Chung-Ang University Gwangmyeong Hospital 154
Not applicableUnknownNCT06158789
What this trial is testing

Repetitive Blood Brain Barrier Opening for Alzheimer's Disease.

Who this might be right for
Alzheimer Disease
Kyung Won Chang 6
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