Not applicableUnknownNCT05902039What this trial is testingMRI Study of Blood-brain Barrier Function in CADASILWho this might be right forCadasilBlood Brain Barrier Defect Peking University First Hospital 100
Post-approval studies (Phase 4)Study completedNCT03639896What this trial is testingEndothelial Injury Mechanism in Elderly Patients Undergoing Major SurgeryWho this might be right forEndothelial DysfunctionBlood Brain Barrier DefectPostoperative Cognitive Dysfunction The First Affiliated Hospital of Anhui Medical University 464
Not applicableUnknownNCT06203015What this trial is testingThe Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive DisorderWho this might be right forMajor Depressive DisorderInflammationCognitive Dysfunction+3 more Lithuanian University of Health Sciences 150
Large-scale testing (Phase 3)Study completedNCT03996447What this trial is testingEfficacy and Safety of Gadopiclenol for Central Nervous System (CNS) Magnetic Resonance Imaging (MRI)Who this might be right forCNS LesionBlood Brain Barrier Defect Guerbet 260
Testing effectiveness (Phase 2)Study completedNCT02633501What this trial is testingP03277 Dose Finding Study in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI)Who this might be right forCNS LesionBlood Brain Barrier Defect Guerbet 312
Testing effectiveness (Phase 2)Looking for participantsNCT07392723What this trial is testingALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older AdultsWho this might be right forCognitive DysfunctionAlzheimer DiseaseBlood-Brain Barrier+3 more Michal Schnaider Beeri, Ph.D. 20
Very early researchStudy completedNCT02389738What this trial is testingBrain Interstitium Temozolomide Concentration Pre and Post Regadenoson AdministrationWho this might be right forBlood Brain Barrier Defect Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 6
Not applicableLooking for participantsNCT07411612What this trial is testingThe Association Between Postoperative Inflammatory and Neurological Serum Biomarker Concentrations and Occurrence of Postoperative DeliriumWho this might be right forDelirium - PostoperativeNeuronal DamageBlood Brain Barrier Defect+2 more Medical University of Vienna 1,170
Testing effectiveness (Phase 2)Active Not RecruitingNCT04876638What this trial is testingMinocycline for Aneurysmal Subarachnoid Hemorrhage (MASH)Who this might be right forAneurysm, RupturedVasospasm, IntracranialDelayed Cerebral Ischemia+1 more University of Southern California 20
Not applicableWithdrawnNCT04096261What this trial is testingThe Importance of Sleep Quality and the Blood-brain Barrier in Cognitive Disorders and Alzheimer's DiseaseWho this might be right forBlood Brain Barrier DefectSleep DeprivationSleep Apnea+1 more Charite University, Berlin, Germany
Not applicableStudy completedNCT03139682What this trial is testingMicrovascular Injury and Blood-brain Barrier Dysfunction as Novel Biomarkers and Targets for Treatment in Traumatic Brain InjuryWho this might be right forTraumatic Brain InjuryBlood Brain Barrier Defect Nova Scotia Health Authority 2