Testing effectiveness (Phase 2)Study completedNCT01009177What this trial is testingEffect of Bosentan in Patients With Metastatic Melanoma Treated With Dacarbazine (DTIC)Who this might be right forMelanoma Actelion 80
Large-scale testing (Phase 3)Study completedNCT01223352What this trial is testingEffects of Two Dosing Regimens of Bosentan in Children With Pulmonary Arterial HypertensionWho this might be right forPulmonary Arterial Hypertension Actelion 64
Testing effectiveness (Phase 2)Ended earlyNCT00226889What this trial is testingTreatment of Early Systemic Sclerosis by BosentanWho this might be right forSystemic Sclerosis (Scleroderma) Rikshospitalet University Hospital 30
Early research (Phase 1)Study completedNCT00260819What this trial is testingEffects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by HypoxiaWho this might be right forHypoxia-Induced Pulmonary Artery Hypertension Assistance Publique - Hôpitaux de Paris 20
Early research (Phase 1)Study completedNCT04991207What this trial is testingEffect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of BosentanWho this might be right forPulmonary Arterial Hypertension Bial - Portela C S.A. 44
Large-scale testing (Phase 3)Study completedNCT00631475What this trial is testingOpen Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443Who this might be right forIdiopathic Pulmonary Fibrosis Actelion 128
Large-scale testing (Phase 3)Study completedNCT00581607What this trial is testingDouble Blind, Randomized Trial of Bosentan for Sarcoidosis Associated Pulmonary HypertensionWho this might be right forSarcoidosisPulmonary Arterial Hypertension University of Cincinnati 43
Post-approval studies (Phase 4)Study completedNCT00433329What this trial is testingCombination Therapy in Pulmonary Arterial HypertensionWho this might be right forPulmonary Arterial Hypertension Actelion 100
Not applicableStudy completedNCT01258504What this trial is testingInfluence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of BosentanWho this might be right forDrug Interactions Gerd Mikus 13
Not applicableStudy completedNCT02798055What this trial is testingBosentan Treatment of Digital Ulcers Related to Systemic SclerosisWho this might be right forSystematic SclerosisDigital UlcerScleroderma Elpen Pharmaceutical Co. Inc. 148
Early research (Phase 1)Study completedNCT02667704What this trial is testingInfluence of Bosentan on the Pharmacokinetics of NintedanibWho this might be right forHealthy Boehringer Ingelheim 13
Very early researchStudy completedNCT01100736What this trial is testingRole of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)Who this might be right forPulmonary Arterial HypertensionVasodilationVasoconstriction University of Edinburgh 10
Post-approval studies (Phase 4)Study completedNCT00303459What this trial is testingEffects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)Who this might be right forPulmonary Arterial Hypertension Actelion 334
Not applicableStudy completedNCT00478296What this trial is testingPulmonary Hypertension in Trisomy 21 PatientsWho this might be right forCongenital Disorders Children's Healthcare of Atlanta 1
Large-scale testing (Phase 3)UnknownNCT02377271What this trial is testingENDOTHELION Study Group: Effect of Bosentan in NAION PatientsWho this might be right forIschemic Optic Neuropathy University Hospital, Grenoble 86
Early research (Phase 1)Study completedNCT05723874What this trial is testingA Study in Healthy Men to Test Whether Bosentan Influences the Amount of BI 425809 in the BloodWho this might be right forHealthy Boehringer Ingelheim 14
Testing effectiveness (Phase 2)Study completedNCT00777985What this trial is testingPreventive Effects of Bosentan on the Systemic Cardiovascular Consequence of Sleep ApneaWho this might be right forObstructive Sleep ApneaHypertension University Hospital, Grenoble 19
Not applicableUnknownNCT01184404What this trial is testingBosentan Improves Clinical Outcome of Adults With Congenital Heart Disease or Mitral Valve Lesions Who Undergo CArdiac SurgeryWho this might be right forCongenital Heart Disease Berto J Bouma 100
Testing effectiveness (Phase 2)Ended earlyNCT00815347What this trial is testingBosentan for Poorly Controlled AsthmaWho this might be right forAsthma UConn Health 11
Large-scale testing (Phase 3)Study completedNCT00319020What this trial is testingBosentan in Children With Pulmonary Arterial Hypertension Extension StudyWho this might be right forPulmonary Arterial Hypertension Actelion 33