Not applicableActive Not RecruitingNCT02116335What this trial is testingEndothelin Receptor Function and Acute StressWho this might be right forHypertension Augusta University 320
Not applicableStudy completedNCT00478296What this trial is testingPulmonary Hypertension in Trisomy 21 PatientsWho this might be right forCongenital Disorders Children's Healthcare of Atlanta 1
Large-scale testing (Phase 3)Study completedNCT00319033What this trial is testingOpen-label Study With Bosentan in Interstitial Lung DiseaseWho this might be right forInterstitial Lung DiseaseScleroderma Actelion 132
Testing effectiveness (Phase 2)Ended earlyNCT00815347What this trial is testingBosentan for Poorly Controlled AsthmaWho this might be right forAsthma UConn Health 11
Testing effectiveness (Phase 2)Study completedNCT00086463What this trial is testingTrial of Iloprost Inhaled Solution as Add-On Therapy With Bosentan in Subjects With Pulmonary Arterial Hypertension (PAH)Who this might be right forPulmonary Arterial HypertensionAyerza SyndromePulmonary Hypertension Actelion 60
Testing effectiveness (Phase 2)Study completedNCT02317679What this trial is testingTreatment of Resistant Port-wine Stains With Bosentan and Pulsed Dye Laser: a Pilot StudyWho this might be right forPort-wine Stains Centre Hospitalier Universitaire de Nice 4
Not applicableWithdrawnNCT00593905What this trial is testingPharmacogenomics in Pulmonary Arterial HypertensionWho this might be right forPulmonary Arterial HypertensionPulmonary HypertensionPAH WHO Group I West Penn Allegheny Health System
Not applicableStudy completedNCT00266903What this trial is testingEisenmenger's Syndrome in Adults With CHDWho this might be right forCongenital Disorders Children's Healthcare of Atlanta 48
Early research (Phase 1)Study completedNCT00260819What this trial is testingEffects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by HypoxiaWho this might be right forHypoxia-Induced Pulmonary Artery Hypertension Assistance Publique - Hôpitaux de Paris 20
Not applicableUnknownNCT05168215What this trial is testingEffectiveness of Bosentan Therapy in Patients With Systemic scleRosis and Progressive Digital ulcEr Disease.Who this might be right forSclerodermaDigital UlcerAutoimmune Diseases+2 more Elpen Pharmaceutical Co. Inc. 300
Early research (Phase 1)Study completedNCT02667704What this trial is testingInfluence of Bosentan on the Pharmacokinetics of NintedanibWho this might be right forHealthy Boehringer Ingelheim 13
Early research (Phase 1)Study completedNCT07081932What this trial is testingA Study in Healthy Men to Test How Bosentan Influences the Amount of Nerandomilast in the BloodWho this might be right forHealthy Boehringer Ingelheim 16
Large-scale testing (Phase 3)UnknownNCT03841734What this trial is testingStudy of the Benefit of Early Treatment With an Endothelin Inhibitor (Bosentan) in Patients With Sudden Blindness Due to Giant Cell Arteritis: CECIBOWho this might be right forArteritis, Giant CellBlindness and Low Vision Centre Hospitalier Universitaire de Nice 8
Post-approval studies (Phase 4)Study completedNCT01779596What this trial is testingET-blockade and Exercise Induced Blood Flow in T2DMWho this might be right forType 2 Diabetes Mellitus Radboud University Medical Center 22
Early research (Phase 1)Study completedNCT05072106What this trial is testingStudy to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid TumorsWho this might be right forAdvanced Solid Tumor PharmaMar 11
Early research (Phase 1)Study completedNCT04101370What this trial is testingBioequivalence Study of Bosentan 125 mg Tablets Immediate Release (IR) Versus Tracleer® 125 mg Tablets IR In Healthy SubjectsWho this might be right forBioequivalence Geropharm 64
Very early researchStudy completedNCT01100736What this trial is testingRole of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)Who this might be right forPulmonary Arterial HypertensionVasodilationVasoconstriction University of Edinburgh 10
Not applicableWithdrawnNCT03139084What this trial is testingEfficacy and Safety of Upfront Combination of ΒΟsentan and ΤΑdalafil in Pulmonary Arterial HypertensionWho this might be right forPulmonary Hypertension Elpen Pharmaceutical Co. Inc.
Not applicableStudy completedNCT01258504What this trial is testingInfluence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of BosentanWho this might be right forDrug Interactions Gerd Mikus 13
Large-scale testing (Phase 3)Study completedNCT00631475What this trial is testingOpen Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443Who this might be right forIdiopathic Pulmonary Fibrosis Actelion 128