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Results for “Brain Metastases From HER2 and Breast Cancer”

24 trials

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Showing 20 of 24 results

Not applicableNot Yet RecruitingNCT07619534
What this trial is testing

Collection of CSF Samples From Participants With Metastatic Triple Negative Breast Cancer (TNBC) and HER2+ Breast Cancer With no Prior History Nor Active Radiographically Detectable Brain Metastases

Who this might be right for
Breast CancerBreast CarcinomaCancer of the Breast+1 more
National Cancer Institute (NCI) 139
Testing effectiveness (Phase 2)Looking for participantsNCT05386108
What this trial is testing

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Who this might be right for
Breast NeoplasmsBrain NeoplasmsNeoplasms by Site+5 more
Stemline Therapeutics, Inc. 73
Testing effectiveness (Phase 2)UnknownNCT04334330
What this trial is testing

Palbociclib, Trastuzumab,Pyrotinib and Fulvestrant Treatment in Patients With Brain Metastasis From ER/PR Positive, HER-2 Positive Breast Cancer: A Multi-center, Prospective Study in China

Who this might be right for
Breast CancerBrain Metastases
Sun Yat-sen University 34
Early research (Phase 1)Looking for participantsNCT06253871
What this trial is testing

A Phase 1/1b Study of IAM1363 in HER2 Cancers

Who this might be right for
HER2 Mutation-Related TumorsHER2HER2-positive Breast Cancer+10 more
Iambic Therapeutics, Inc 383
Early research (Phase 1)Study completedNCT00470847
What this trial is testing

Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer

Who this might be right for
Breast CancerBrain Metastases
Nancy Lin, MD 35
Testing effectiveness (Phase 2)UnknownNCT04639271
What this trial is testing

Pyrotinib, Trastuzumab And Abraxane in HER2-positive MBC With Brain Metastasis

Who this might be right for
Breast CancerHER2-positive Breast Cancer
Shandong Cancer Hospital and Institute 100
Early research (Phase 1)Active Not RecruitingNCT03696030
What this trial is testing

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

Who this might be right for
Malignant NeoplasmMetastatic Malignant Neoplasm in the BrainMetastatic Malignant Neoplasm in the Leptomeninges+2 more
City of Hope Medical Center 24
Early research (Phase 1)Study completedNCT01921335
What this trial is testing

ARRY-380 + Trastuzuamab for Breast w/ Brain Mets

Who this might be right for
Brain Metastases From HER2 and Breast CancerAdvanced HER2-positive Breast Cancer
Dana-Farber Cancer Institute 41
Early research (Phase 1)Ended earlyNCT05553522
What this trial is testing

Tucatinib, Trastuzumab, and Capecitabine With SRS for Brain Metastases From HER-2 Positive Breast Cancer

Who this might be right for
Brain MetastasesHER2-positive Breast Cancer
Baptist Health South Florida 1
Early research (Phase 1)Study completedNCT02135159
What this trial is testing

Patients With Brain Metastases From HER2-positive Breast Cancer

Who this might be right for
HER2-positive Breast Cancer
Institut du Cancer de Montpellier - Val d'Aurelle 36
Testing effectiveness (Phase 2)Study completedNCT01622868
What this trial is testing

Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer

Who this might be right for
HER2-Positive Breast CarcinomaInvasive Breast CarcinomaMetastatic Malignant Neoplasm in the Brain+2 more
National Cancer Institute (NCI) 143
Large-scale testing (Phase 3)UnknownNCT03613181
What this trial is testing

ANG1005 in Leptomeningeal Disease From Breast Cancer

Who this might be right for
Leptomeningeal CarcinomatosisLeptomeningeal MetastasesBrain Metastases+1 more
Angiochem Inc 150
Testing effectiveness (Phase 2)Looking for participantsNCT04348747
What this trial is testing

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Malignant Neoplasm in the BrainMetastatic Triple-Negative Breast Carcinoma+1 more
Roswell Park Cancer Institute 23
Testing effectiveness (Phase 2)Study completedNCT01441596
What this trial is testing

Lux-Breast 3; Afatinib Alone or in Combination With Vinorelbine in Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer Suffering From Brain Metastases

Who this might be right for
Breast NeoplasmsNeoplasm Metastasis
Boehringer Ingelheim 121
Testing effectiveness (Phase 2)Ended earlyNCT01363986
What this trial is testing

Herceptin (Trastuzumab) in Combination With Whole Brain Radiotherapy in Patients With HER-2 Positive Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 3
Testing effectiveness (Phase 2)Looking for participantsNCT06839560
What this trial is testing

Evaluating the Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With VEX Metronomic Chemotherapy and Concurrent or Delayed Radiotherapy in Patients With Advanced HER2-Negative Breast Cancer With Brain Metastasis

Who this might be right for
Brain Metastasis From Advanced HER2-negative Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 102
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06462079
What this trial is testing

Sacituzumab Govitecan Combined With Head Radiotherapy for Her2-negative Breast Cancer Brain Metastases

Who this might be right for
Brain Metastasis
Guangzhou Medical University 43
Not applicableStudy completedNCT02898727
What this trial is testing

Local Therapy for the Treatment of Brain Metastases From HER2 Positive Breast Cancer

Who this might be right for
Breast Neoplasms
Trans Tasman Radiation Oncology Group 25
Testing effectiveness (Phase 2)Ended earlyNCT01217411
What this trial is testing

RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer

Who this might be right for
Adult Solid NeoplasmExtensive Stage Lung Small Cell CarcinomaHER2/Neu Negative+10 more
National Cancer Institute (NCI) 5
Testing effectiveness (Phase 2)WithdrawnNCT03637868
What this trial is testing

Eribulin in Brain Metastases From HER2-negative Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Institut Paoli-Calmettes
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