Testing effectiveness (Phase 2)Study completedNCT01469247What this trial is testingDiffuse Intrinsic Pontine Glioma (DIPG) Reirradiation (ReRT)Who this might be right forBrain Cancer M.D. Anderson Cancer Center 12
Testing effectiveness (Phase 2)Study completedNCT04238819What this trial is testingAbemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including NeuroblastomaWho this might be right forRelapsed Solid TumorRefractory Solid Tumor Eli Lilly and Company 47
Very early researchActive Not RecruitingNCT03893487What this trial is testingFimepinostat in Treating Brain Tumors in Children and Young AdultsWho this might be right forDiffuse Intrinsic Pontine GliomaRecurrent Anaplastic AstrocytomaRecurrent Glioblastoma+2 more Sabine Mueller, MD, PhD 30
Testing effectiveness (Phase 2)UnknownNCT02233049What this trial is testingBiological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) EradicationWho this might be right forDiffuse Intrinsic Pontine Glioma Gustave Roussy, Cancer Campus, Grand Paris 250
Early research (Phase 1)Ended earlyNCT01400672What this trial is testingImiquimod/Brain Tumor Initiating Cell (BTIC) Vaccine in Brain Stem GliomaWho this might be right forDiffuse Intrinsic Pontine Glioma Masonic Cancer Center, University of Minnesota 8
Early research (Phase 1)Ended earlyNCT03396575What this trial is testingBrain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)Who this might be right forDiffuse Intrinsic Pontine Glioma (DIPG)Brain Stem Glioma University of Florida 11
Early research (Phase 1)Study completedNCT01688401What this trial is testingIntra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).Who this might be right forDiffuse Intrinsic Pontine Glioma (DIPG) Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 3
Testing effectiveness (Phase 2)Temporarily pausedNCT05123534What this trial is testingSonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPGWho this might be right forDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma SonALAsense, Inc. 15
Testing effectiveness (Phase 2)Looking for participantsNCT05278208What this trial is testingLutathera for Treatment of Recurrent or Progressive High-Grade CNS TumorsWho this might be right forHigh Grade GliomaMeningiomaEmbryonal Tumor+10 more Nationwide Children's Hospital 65
Early research (Phase 1)Looking for participantsNCT05298995What this trial is testingGD2-CAR T Cells for Pediatric Brain TumoursWho this might be right forBrain Tumor, PediatricMedulloblastoma, ChildhoodEmbryonal Tumor+4 more Bambino Gesù Hospital and Research Institute 54
Not applicableActive Not RecruitingNCT03739372What this trial is testingClinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade GliomaWho this might be right forGliomaGlioma of BrainCancer+5 more University of California, San Francisco 44
Not applicableLooking for participantsNCT03101813What this trial is testingInternational Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and RepositoryWho this might be right forDiffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-MutantDiffuse Midline Glioma Children's Hospital Medical Center, Cincinnati 1,500
Early research (Phase 1)Ended earlyNCT04804709What this trial is testingNon-Invasive Focused Ultrasound (FUS) With Oral Panobinostat in Children With Progressive Diffuse Midline Glioma (DMG)Who this might be right forDiffuse Intrinsic Pontine GliomaDiffuse Pontine and Thalamic GliomasDiffuse Midline Glioma, H3 K27M-Mutant Columbia University 5
Testing effectiveness (Phase 2)Looking for participantsNCT05843253What this trial is testingStudy of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutantWho this might be right forHigh Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more Nationwide Children's Hospital 120
Testing effectiveness (Phase 2)Looking for participantsNCT05615623What this trial is testingBlood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPGWho this might be right forBrain Tumor InSightec 10
Testing effectiveness (Phase 2)Study completedNCT00036569What this trial is testingA Phase II Study of Pegylated Interferon Alfa 2b (PEG-Intron(Trademark)) in Children With Diffuse Pontine GliomasWho this might be right forDiffuse Intrinsic Pontine Glioma National Cancer Institute (NCI) 32
Testing effectiveness (Phase 2)Ended earlyNCT02607124What this trial is testingA Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation TherapyWho this might be right forHigh Grade GliomaDiffuse Intrinsic Pontine GliomaBithalamic High Grade Glioma Children's Hospital Medical Center, Cincinnati 11
Early research (Phase 1)Study completedNCT04264143What this trial is testingCED of MTX110 Newly Diagnosed Diffuse Midline GliomasWho this might be right forDiffuse Intrinsic Pontine GliomaDiffuse Pontine and Thalamic GliomasDiffuse Midline Glioma Luca Szalontay 9
Early research (Phase 1)Study completedNCT04749641What this trial is testingNeoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine GliomaWho this might be right forDiffuse Intrinsic Pontine Glioma Yang Zhang 16
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06639607What this trial is testingPEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and EpendymomaWho this might be right forDiffuse Midline GliomaDiffuse Midline High-grade GliomaMedulloblastoma+1 more Washington University School of Medicine 68