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Results for “Breast Cancer Brain Metastases”

255 trials

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Showing 20 of 255 results

Post-approval studies (Phase 4)Looking for participantsNCT05376878
What this trial is testing

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain
City of Hope Medical Center 10
Large-scale testing (Phase 3)Ended earlyNCT04395339
What this trial is testing

GM1 Prophylaxis for WBRT Related Cognitive Dysfunction

Who this might be right for
Brain MetastasesRadiotherapy Side EffectCognitive Impairment+2 more
Sun Yat-sen University 51
Testing effectiveness (Phase 2)Looking for participantsNCT04923542
What this trial is testing

SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain Metastases

Who this might be right for
Brain MetastasesHR+ Metastatic Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT04538742
What this trial is testing

A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AstraZeneca 245
Not applicableLooking for participantsNCT06330870
What this trial is testing

Brain Metastasis Development Mechanism in BCBM Patients

Who this might be right for
Breast CancerBrain Metastasis
Samsung Medical Center 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05593094
What this trial is testing

Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsHER2-positive Breast Cancer
Hoffmann-La Roche 210
Early research (Phase 1)Study completedNCT03807765
What this trial is testing

Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases

Who this might be right for
Metastatic Breast CancerBrain Metastases
H. Lee Moffitt Cancer Center and Research Institute 14
Testing effectiveness (Phase 2)Looking for participantsNCT04348747
What this trial is testing

Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Malignant Neoplasm in the BrainMetastatic Triple-Negative Breast Carcinoma+1 more
Roswell Park Cancer Institute 23
Not applicableLooking for participantsNCT07511933
What this trial is testing

Novel Ga68-PSMA PET/CT-tracer to Differentiate Between Radiation Necrosis and Tumor Progression in Brain Metastases

Who this might be right for
Brain Metastases From Non-small Cell Lung Cancer (NSCLC)Brain Metastases From MelanomaBrain Metastases From Breast Cancer
The Netherlands Cancer Institute 100
Testing effectiveness (Phase 2)UnknownNCT03412955
What this trial is testing

A Pilot Study of Eribulin in Breast Cancer (BC) Patients With Brain Metastases Previously Treated With Anthracyclines and Taxanes

Who this might be right for
Breast Cancer
Tan Tock Seng Hospital 14
Testing effectiveness (Phase 2)Looking for participantsNCT05866432
What this trial is testing

Phase II Study of Dato-DXd in Triple-negative Breast Cancer Patients With Newly Diagnosed or Progressing Brain Metastases

Who this might be right for
Breast Cancer Stage IV
Medical University of Vienna 20
Large-scale testing (Phase 3)UnknownNCT05144867
What this trial is testing

Stereotactic Radiosurgery vs Whole Brain Radiotherapy in Breast Cancer With Brain Oligometastasis

Who this might be right for
Breast CancerBrain Metastases, AdultStereotactic Radiosurgery+1 more
Post Graduate Institute of Medical Education and Research, Chandigarh 98
Testing effectiveness (Phase 2)WithdrawnNCT03203616
What this trial is testing

Kadcyla In pAtients With bRAin Metastasis

Who this might be right for
Metastatic HER2-positive Breast Cancer With Brain Metastasis
Jules Bordet Institute
Testing effectiveness (Phase 2)Study completedNCT01622868
What this trial is testing

Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer

Who this might be right for
HER2-Positive Breast CarcinomaInvasive Breast CarcinomaMetastatic Malignant Neoplasm in the Brain+2 more
National Cancer Institute (NCI) 143
Early research (Phase 1)Study completedNCT02223052
What this trial is testing

Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies

Who this might be right for
Hematological NeoplasmsNon-Hodgkin's LymphomaHodgkin's Lymphoma+17 more
Celgene 89
Testing effectiveness (Phase 2)UnknownNCT04158947
What this trial is testing

HER2+ Breast Cancer Patients With Active Brain Metastases Treated With Afatinib & T-DM1 vs. T-DM1 Alone

Who this might be right for
HER2-positive Breast CancerBrain Metastases
xuexin he 130
Testing effectiveness (Phase 2)Ended earlyNCT02669914
What this trial is testing

MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived Tumors

Who this might be right for
Non-Small Cell Lung CancerNonsmall Cell Lung CancerBreast Cancer+15 more
Washington University School of Medicine 4
Testing effectiveness (Phase 2)Looking for participantsNCT06839560
What this trial is testing

Evaluating the Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With VEX Metronomic Chemotherapy and Concurrent or Delayed Radiotherapy in Patients With Advanced HER2-Negative Breast Cancer With Brain Metastasis

Who this might be right for
Brain Metastasis From Advanced HER2-negative Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 102
Large-scale testing (Phase 3)Looking for participantsNCT03418961
What this trial is testing

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

Who this might be right for
CardiotoxicityHER2/Neu PositiveMetastatic Malignant Neoplasm in the Brain+2 more
SWOG Cancer Research Network 491
Testing effectiveness (Phase 2)Study completedNCT00263588
What this trial is testing

Lapatinib for Brain Metastases In ErbB2-Positive Breast Cancer

Who this might be right for
Neoplasms, Breast
Novartis Pharmaceuticals 242
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