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Results for “Brutons Tyrosine Kinase”

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Showing 20 of 0 results

Not applicableLooking for participantsNCT06151730
What this trial is testing

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

Who this might be right for
Chronic Lymphocytic LeukemiaHematopoietic and Lymphoid System NeoplasmMantle Cell Lymphoma+2 more
Mayo Clinic 100
Early research (Phase 1)Active Not RecruitingNCT02717624
What this trial is testing

Acalabrutinib in Combination With Rituximab + (Bendamustine or Venetoclax) in Subjects With MCL

Who this might be right for
Mantle Cell Lymphoma (MCL)
Acerta Pharma BV 72
Early research (Phase 1)Study completedNCT05245396
What this trial is testing

Study Comparing Pharmacokinetics of Different Formulations of Evobrutinib in Healthy Participants

Who this might be right for
Healthy
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 58
Testing effectiveness (Phase 2)Active Not RecruitingNCT02213926
What this trial is testing

An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma

Who this might be right for
Mantle Cell Lymphoma (MCL)
Acerta Pharma BV 124
Testing effectiveness (Phase 2)Study completedNCT04402138
What this trial is testing

Treatment With Acalabrutinib Post Blood or Marrow Transplantation in Subjects With Mantle Cell Lymphoma

Who this might be right for
Mantle Cell Lymphoma
SCRI Development Innovations, LLC 15
Testing effectiveness (Phase 2)Study completedNCT01752426
What this trial is testing

Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLL

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 30
Large-scale testing (Phase 3)Study completedNCT04411641
What this trial is testing

Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (HERCULES)

Who this might be right for
Non-relapsing Secondary Progressive Multiple Sclerosis
Sanofi 1,131
Large-scale testing (Phase 3)Active Not RecruitingNCT04662255
What this trial is testing

Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL)

Who this might be right for
Lymphoma, Mantle-Cell
Loxo Oncology, Inc. 500
Large-scale testing (Phase 3)Study completedNCT01646021
What this trial is testing

Study of Ibrutinib (a Bruton's Tyrosine Kinase Inhibitor), Versus Temsirolimus in Patients With Relapsed or Refractory Mantle Cell Lymphoma Who Have Received at Least One Prior Therapy

Who this might be right for
Mantle Cell Lymphoma
Janssen Research & Development, LLC 280
Large-scale testing (Phase 3)Active Not RecruitingNCT06799000
What this trial is testing

Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE 1)

Who this might be right for
Hidradenitis Suppurativa
Novartis Pharmaceuticals 588
Not applicableEnrolling By InvitationNCT06211413
What this trial is testing

Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors

Who this might be right for
Chronic Lymphocytic LeukemiaAtrial FibrillationHypertension+1 more
Abramson Cancer Center at Penn Medicine 50
Large-scale testing (Phase 3)Looking for participantsNCT01804686
What this trial is testing

A Long-term Extension Study of PCI-32765 (Ibrutinib)

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaMantle Cell Lymphoma+4 more
Janssen Research & Development, LLC 700
Testing effectiveness (Phase 2)Study completedNCT01109069
What this trial is testing

Safety and Tolerability Study of PCI-32765 in B Cell Lymphoma and Chronic Lymphocytic Leukemia

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaDiffuse Well-differentiated Lymphocytic Lymphoma+7 more
Pharmacyclics LLC. 199
Large-scale testing (Phase 3)Study completedNCT01776840
What this trial is testing

The Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma

Who this might be right for
Mantle Cell Lymphoma
Janssen Research & Development, LLC 523
Testing effectiveness (Phase 2)Ended earlyNCT02272686
What this trial is testing

Ibrutinib Post Stem Cell Transplantation (SCT) in Double-Hit B-Cell Lymphoma

Who this might be right for
Lymphoma
M.D. Anderson Cancer Center 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT04234061
What this trial is testing

Clinical Trial to Assess The Efficacy and Safety of the Combination of Tisagenlecleucel And Ibrutinib in Mantle Cell Lymphoma

Who this might be right for
Mantle Cell Lymphoma Recurrent
Peter MacCallum Cancer Centre, Australia 20
Large-scale testing (Phase 3)Looking for participantsNCT07277231
What this trial is testing

Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic Leukemia
BeOne Medicines 500
Testing effectiveness (Phase 2)Looking for participantsNCT07271667
What this trial is testing

Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

Who this might be right for
Chronic Lymphocytic LeukemiaB-cell Malignancies
Curis, Inc. 108
Early research (Phase 1)Ended earlyNCT02292225
What this trial is testing

Duvelisib With Obinutuzumab in Patients With CLL/SLL Previously Treated With a BTKi (SYNCHRONY)

Who this might be right for
Lymphocytic Leukemia, ChronicLymphoma, Small Lymphocytic
SecuraBio 3
Not applicableStudy completedNCT04938141
What this trial is testing

MEOI and HRQoL in CLL Patients Treated With BTKis

Who this might be right for
Chronic Lymphocytic Leukemia
AstraZeneca 23
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