Not applicableNo Longer AvailableNCT02094222What this trial is testingExpanded Access Protocol for an Intermediate Size Population - RAVICTI for Byler DiseaseWho this might be right forByler Disease Robert Squires, Jr.
Not applicableLooking for participantsNCT06193928What this trial is testingLong-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)Who this might be right forAlagille SyndromeProgressive Familial Intrahepatic Cholestasis Mirum Pharmaceuticals, Inc. 70
Not applicableEnded earlyNCT01200082What this trial is testingSulfation of Bile Acids as a Biomarker for Hepatobiliary DiseasesWho this might be right forHepatobiliary Diseases University of Nebraska 430
Not applicableLooking for participantsNCT06777914What this trial is testingFamilial Intrahepatic Cholestasis-related Genes Associated with Disease Susceptibility in Hepato-biliary CancersWho this might be right forHepatobiliary CancersProgressive Familial Intrahepatic Cholestasis (PFIC)Cholestatic Liver Disease IRCCS Azienda Ospedaliero-Universitaria di Bologna 600
Early research (Phase 1)Study completedNCT03082937What this trial is testingAn Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy SubjectsWho this might be right forOrphan Cholestatic Liver DiseasesProgressive Familial Intrahepatic CholestasisAlagille Syndrome+1 more Albireo 6
Not applicableNo Longer AvailableNCT01949766What this trial is testingTransition From Buphenyl to RAVICTI for the Therapy of Byler DiseaseWho this might be right forByler Disease University of Pittsburgh
Not applicableLooking for participantsNCT07317193What this trial is testingDEFINING THE GENETIC DRIVERS OF ADULT-ONSET CHOLESTATIC LIVER DISEASEWho this might be right forCholestatic Liver DiseaseProgressive Familial Intrahepatic Cholestasis Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 60
Large-scale testing (Phase 3)Study completedNCT04185363What this trial is testingAn Extension Study of Maralixibat in Patients With Progressive Familial Intrahepatic Cholestasis (PFIC)Who this might be right forProgressive Familial Intrahepatic Cholestasis (PFIC) Mirum Pharmaceuticals, Inc. 90
Not applicableEnrolling By InvitationNCT03930810What this trial is testingNAtural Course and Prognosis of PFIC and Effect of Biliary DiversionWho this might be right forProgressive Familial Intrahepatic Cholestasis University Medical Center Groningen 1,500
Large-scale testing (Phase 3)WithdrawnNCT03353454What this trial is testingA Placebo-controlled Study of Maralixibat (SHP625) in Pediatric Subjects With Progressive Familial Intrahepatic Cholestasis (PFIC)Who this might be right forProgressive Familial Intrahepatic Cholestasis (PFIC) Mirum Pharmaceuticals, Inc.
Not applicableLooking for participantsNCT05704517What this trial is testingProgressive Familial Intrahepatic Cholestasis in Indian Children - Establishing an Indian PFIC RegistryWho this might be right forProgressive Familial Intrahepatic Cholestasis Institute of Liver and Biliary Sciences, India 200
Large-scale testing (Phase 3)Study completedNCT03659916What this trial is testingLong Term Safety & Efficacy Study Evaluating The Effect of A4250 in Children With PFICWho this might be right forProgressive Familial Intrahepatic Cholestasis Albireo, an Ipsen Company 116
Not applicableUnknownNCT04071197What this trial is testingGastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport DisordersWho this might be right forProgressive Familial Intrahepatic Cholestasis National Liver Institute, Egypt 20
Not applicableStudy completedNCT05687474What this trial is testingBaby Detect : Genomic Newborn ScreeningWho this might be right forCongenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more Centre Hospitalier Universitaire de Liege 6,824
Not applicableNot Yet RecruitingNCT06506734What this trial is testingDental Dyschromia and Quality of Life in Early Prolonged HyperbilirubinemiaWho this might be right forDental Diseases University Hospital, Toulouse 120
Large-scale testing (Phase 3)Study completedNCT03566238What this trial is testingThis Study Will Investigate the Efficacy and Safety of A4250 in Children With PFIC Types 1 or 2Who this might be right forPFIC1PFIC2 Albireo 62
Not applicableLooking for participantsNCT06778174What this trial is testingProspective Analysis of the Treatment of Progressive Familial Intrahepatic Cholestasis (TreatFIC)Who this might be right forProgressive Familial Intrahepatic Cholestasis University Medical Center Groningen 200
Not applicableStudy completedNCT02131623What this trial is testingValidation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver DiseaseWho this might be right forAlagille SyndromeProgressive Familial Intrahepatic Cholestasis Mirum Pharmaceuticals, Inc. 23
Not applicableApproved For MarketingNCT04483531What this trial is testingOdevixibat for the Treatment of Progressive Familial Intrahepatic CholestasisWho this might be right forProgressive Familial Intrahepatic Cholestasis Albireo
Not applicableNot Yet RecruitingNCT07293897What this trial is testingA Database Study of Maralixibat (TAK-625) in Participants With Alagille Syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC)Who this might be right forAlagille Syndrome (ALGS)Progressive Familial Intrahepatic Cholestasis (PFIC) Takeda 50