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Results for “C3 Glomerulonephritis”

24 trials

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Showing 20 of 24 results

Large-scale testing (Phase 3)Looking for participantsNCT03955445
What this trial is testing

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

Who this might be right for
C3 GlomerulopathyImmune-complex-membranoproliferative Glomerulonephritis
Novartis Pharmaceuticals 225
Testing effectiveness (Phase 2)Looking for participantsNCT06209736
What this trial is testing

Safety and Efficacy Study of OMS906 in Patients With C3G and ICGN

Who this might be right for
C3 GlomerulopathyIdiopathic Immune Complex-Mediated Glomerulonephritis
Omeros Corporation 20
Large-scale testing (Phase 3)Active Not RecruitingNCT05809531
What this trial is testing

An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc. 100
Testing effectiveness (Phase 2)Study completedNCT03095118
What this trial is testing

Daratumumab in Treatment of PGNMID and C3 GN

Who this might be right for
Membranoproliferative Glomerulonephritis
Fernando Fervenza 12
Large-scale testing (Phase 3)Study completedNCT05067127
What this trial is testing

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc. 124
Testing effectiveness (Phase 2)Active Not RecruitingNCT04572854
What this trial is testing

Study Assessing the Safety and Efficacy of Pegcetacoplan in Post-Transplant Recurrence of C3G or IC-MPGN

Who this might be right for
C3GIC-MPGNRenal Transplant+9 more
Apellis Pharmaceuticals, Inc. 13
Not applicableUnknownNCT06126471
What this trial is testing

Prevalence and Pathological Features of C3 Dominant Glomerulonephritis Among Egyptian Population

Who this might be right for
C3 Nephropathy
Sohag University 100
Testing effectiveness (Phase 2)Study completedNCT03124368
What this trial is testing

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

Who this might be right for
C3 GlomerulonephritisDense Deposit DiseaseC3 Glomerulopathy+2 more
Alexion Pharmaceuticals, Inc. 6
Testing effectiveness (Phase 2)Study completedNCT03453619
What this trial is testing

Phase II Study Assessing Safety and Efficacy of APL-2 in Glomerulopathies

Who this might be right for
IgA NephropathyLupus NephritisMembranous Nephropathy+2 more
Apellis Pharmaceuticals, Inc. 21
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06786338
What this trial is testing

SGB-9768 in Patients with Complement-mediated Kidney Diseases

Who this might be right for
IgA Nephropathy (IgAN)C3 GlomerulopathyIC-MPGN
Suzhou Sanegene Bio Inc. 38
Testing effectiveness (Phase 2)Study completedNCT03301467
What this trial is testing

Controlled Trial Evaluating Avacopan in C3 Glomerulopathy

Who this might be right for
C3 Glomerulopathy (C3G)
Amgen 57
Testing effectiveness (Phase 2)Study completedNCT03369236
What this trial is testing

A Proof-of-Concept Study of Danicopan for 6 Months of Treatment in Participants With C3 Glomerulopathy (C3G)

Who this might be right for
C3 GlomerulopathyC3 GlomerulonephritisDense Deposit Disease
Alexion Pharmaceuticals, Inc. 13
Testing effectiveness (Phase 2)WithdrawnNCT06419205
What this trial is testing

Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

Who this might be right for
IgA NephropathyLupus Nephritis (LN)C3 (Complement Component 3) Glomerulopathy
Q32 Bio Inc.
Early research (Phase 1)WithdrawnNCT02302755
What this trial is testing

TP10 Use in Patients With C3 Glomerulopathy (C3G)

Who this might be right for
Dense Deposit Disease
University of Iowa
Testing effectiveness (Phase 2)Looking for participantsNCT04183101
What this trial is testing

Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

Who this might be right for
C3 GlomerulopathyMembranoproliferative GlomerulonephritisComplement Abnormality+2 more
Region Skane 30
Early research (Phase 1)Ended earlyNCT01791686
What this trial is testing

Clinical Trial of CDX-1135 in Pediatric and Adult Patients With Dense Deposit Disease

Who this might be right for
Dense Deposit DiseaseMembranoproliferative Glomerulonephritis Type IIC3 Glomerulonephritis
Celldex Therapeutics 1
Testing effectiveness (Phase 2)Ended earlyNCT03459443
What this trial is testing

A Proof of Concept Study for a 12 Month Treatment in Patients With C3G or IC-MPGN Treated With ACH-0144471

Who this might be right for
C3 GlomerulonephritisC3 GlomerulopathyImmune Complex Membranoproliferative Glomerulonephritis+2 more
Alexion Pharmaceuticals, Inc. 22
Testing effectiveness (Phase 2)Study completedNCT03832114
What this trial is testing

Study on Efficacy and Safety of LNP023 in C3 Glomerulopathy Patients Transplanted and Not Transplanted

Who this might be right for
Glomerulonephritis
Novartis Pharmaceuticals 27
Not applicableApproved For MarketingNCT04729062
What this trial is testing

C3G/Primary IC-MPGN EAP

Who this might be right for
C3GIC-MPGNC3 Glomerulopathy+9 more
Apellis Pharmaceuticals, Inc.
Early research (Phase 1)Study completedNCT01221181
What this trial is testing

Eculizumab Therapy for Dense Deposit Disease and C3 Nephropathy

Who this might be right for
Dense Deposit DiseaseMembranoproliferative Glomerulonephritis
Columbia University 6
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