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Results for “CAR NK”

171 trials

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Showing 20 of 171 results

Early research (Phase 1)UnknownNCT04004637
What this trial is testing

CD7 CAR-T Cells for Patients With R/R CD7+ NK/T Cell Lymphoma,T-lymphoblastic Lymphoma and Acute Lymphocytic Leukemia

Who this might be right for
T-lymphoblastic LymphomaNK/T Cell LymphomaAcute Lymphocytic Leukemia
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10
Early research (Phase 1)UnknownNCT05213195
What this trial is testing

NKG2D CAR-NK Cell Therapy in Patients With Refractory Metastatic Colorectal Cancer

Who this might be right for
Refractory Metastatic Colorectal Cancer
Zhejiang University 38
Very early researchActive Not RecruitingNCT06596057
What this trial is testing

Safety and Efficacy of CD19 CAR-T/CAR-NK Cells

Who this might be right for
Safety and Efficacy
The Second Hospital of Shandong University 10
Very early researchUnknownNCT03692767
What this trial is testing

Study of Anti-CD22 CAR NK Cells in Relapsed and Refractory B Cell Lymphoma

Who this might be right for
Refractory B-Cell Lymphoma
Allife Medical Science and Technology Co., Ltd. 9
Early research (Phase 1)Active Not RecruitingNCT06358430
What this trial is testing

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Who this might be right for
Colorectal CancerMinimal Residual Disease
M.D. Anderson Cancer Center 10
Testing effectiveness (Phase 2)Looking for participantsNCT07627711
What this trial is testing

Dual-Target CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma

Who this might be right for
Pancreatic Ductal Adenocarcinoma (PDAC)Unresectable Locally AdvancedMetastatic Disease
Beijing Biotech 42
Early research (Phase 1)UnknownNCT04796675
What this trial is testing

Cord Blood Derived Anti-CD19 CAR-Engineered NK Cells for B Lymphoid Malignancies

Who this might be right for
Acute Lymphocytic LeukemiaChronic Lymphocytic LeukemiaNon Hodgkin's Lymphoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 27
Early research (Phase 1)Study completedNCT05563545
What this trial is testing

Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Shanghai Simnova Biotechnology Co.,Ltd. 2
Very early researchLooking for participantsNCT07283315
What this trial is testing

Exploratory Clinical Study of Second-generation CD19/BCMA Chimeric Antigen Receptor NK Cell Injection in Treating Paediatric B Cell-related Autoimmune Diseases

Who this might be right for
Paediatric B Cell-related Autoimmune DiseasesAutoimmune DiseasesCAR
The Children's Hospital of Zhejiang University School of Medicine 12
Early research (Phase 1)Looking for participantsNCT05410717
What this trial is testing

CLDN6/GPC3/Mesothelin/AXL-CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
Stage IV Ovarian CancerTestis Cancer, RefractoryEndometrial Cancer Recurrent+1 more
Second Affiliated Hospital of Guangzhou Medical University 200
Early research (Phase 1)Active Not RecruitingNCT04288726
What this trial is testing

Allogeneic CD30.CAR-EBVSTs in Patients With Relapsed or Refractory CD30-Positive Lymphomas

Who this might be right for
Extranodal Natural Killer/T-Cell Lymphoma, Nasal TypeClassical Hodgkin Lymphoma
Baylor College of Medicine 27
Not applicableUnknownNCT05776355
What this trial is testing

NKG2D CAR-NK & Ovarian Cancer

Who this might be right for
Ovarian Cancer
Hangzhou Cheetah Cell Therapeutics Co., Ltd 18
Testing effectiveness (Phase 2)UnknownNCT02274584
What this trial is testing

CAR T Cells Targeting CD30 Positive Lymphomas (4SCAR30273)

Who this might be right for
Lymphomas
Peking University 20
Very early researchUnknownNCT05194709
What this trial is testing

Study of Anti-5T4 CAR-NK Cell Therapy in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Wuxi People's Hospital 40
Very early researchNot Yet RecruitingNCT07243366
What this trial is testing

Allogeneic CD19-CAR-NK Cells in Patients With Refractory Myasthenia Gravis

Who this might be right for
Refractory Myasthenia Gravis
Guangdong ProCapZoom Biosciences Co., Ltd. 15
Testing effectiveness (Phase 2)WithdrawnNCT03579927
What this trial is testing

CAR.CD19-CD28-zeta-2A-iCasp9-IL15-Transduced Cord Blood NK Cells, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Participants With B-cell Lymphoma

Who this might be right for
CD19 PositiveMantle Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma+4 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Looking for participantsNCT05092451
What this trial is testing

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

Who this might be right for
B-Cell LymphomaMyelodysplastic Syndromes (MDS)Acute Myeloid Leukemia (AML)+7 more
M.D. Anderson Cancer Center 80
Testing effectiveness (Phase 2)Study completedNCT06006403
What this trial is testing

Safety and Efficacy of CD123-targeted CAR-NK for Relapsed/Refractory Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasm

Who this might be right for
Acute Myeloid LeukemiaBlastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)Relapse Leukemia+1 more
Chongqing Precision Biotech Co., Ltd 5
Testing effectiveness (Phase 2)Looking for participantsNCT07486089
What this trial is testing

Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC)

Who this might be right for
Breast Cancer (Locally Advanced or Metastatic)HER2-positive Breast CancerTriple-Negative Breast Cancer (TNBC)
Beijing Biotech 60
Early research (Phase 1)Looking for participantsNCT07579208
What this trial is testing

A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma

Who this might be right for
Phase 1NK CellIL13Ra+4 more
M.D. Anderson Cancer Center 36
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