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Results for “CAR-T Cell Immunotherapy”

240 trials

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Showing 20 of 240 results

Early research (Phase 1)WithdrawnNCT04094766
What this trial is testing

Safety and Efficacy of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy in R/R Acute B Lymphoblastic Leukemia

Who this might be right for
Refractory B Acute Lymphoblastic LeukemiaRelapse B Acute Lymphoblastic Leukemia
Second Affiliated Hospital of Xi'an Jiaotong University
Early research (Phase 1)UnknownNCT03086954
What this trial is testing

Study Evaluating the Efficacy and Safety With CAR-T Immunotherapy for CD19 Positive Lymphoma

Who this might be right for
Lymphoma
Sinobioway Cell Therapy Co., Ltd. 24
Not applicableLooking for participantsNCT06541327
What this trial is testing

Cellular Immunotherapy for Relapsed or Refractory Lymphoma Data Collection

Who this might be right for
Lymphoma, Non-Hodgkin
Ruijin Hospital 1,000
Testing effectiveness (Phase 2)WithdrawnNCT02723942
What this trial is testing

CAR-T Cell Immunotherapy for HCC Targeting GPC3

Who this might be right for
GPC3 Positive Hepatocellular CarcinomaCAR-T Cell Immunotherapy
Fuda Cancer Hospital, Guangzhou
Large-scale testing (Phase 3)Ended earlyNCT05664217
What this trial is testing

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Who this might be right for
Non-Hodgkin LymphomaRelapsed/Refractory Diffuse Large B-cell Lymphoma
Nektar Therapeutics 15
Testing effectiveness (Phase 2)Looking for participantsNCT04422912
What this trial is testing

A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

Who this might be right for
Pemphigus Vulgaris
Cabaletta Bio 40
Early research (Phase 1)Looking for participantsNCT05354375
What this trial is testing

Clinical Study of PSMA-targeted CAR-T Cells in the Treatment of Castration-resistant Prostate Cancer

Who this might be right for
Immunotherapy
The Affiliated Hospital of Xuzhou Medical University 20
Early research (Phase 1)Looking for participantsNCT04969354
What this trial is testing

Clinical Study of CAIX-targeted CAR-T Cells in the Treatment of Advanced Renal Cell Carcinoma

Who this might be right for
Immunotherapy
The Affiliated Hospital of Xuzhou Medical University 20
Early research (Phase 1)Active Not RecruitingNCT02935257
What this trial is testing

Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19

Who this might be right for
Leukemia, Lymphoblastic, Acute, Lymphoma
University College, London 72
Testing effectiveness (Phase 2)UnknownNCT04430530
What this trial is testing

4SCAR-T Therapy Post CD19-targeted Immunotherapy

Who this might be right for
CD19 Negative B-cell Malignancies
Shenzhen Geno-Immune Medical Institute 100
Early research (Phase 1)UnknownNCT02721407
What this trial is testing

Anti-CD22 CAR-T Therapy for CD19-refractory or Resistant Lymphoma Patients

Who this might be right for
Recurrent Adult Diffuse Large Cell LymphomaRecurrent Follicular LymphomaRecurrent Mantle Cell Lymphoma+3 more
Xinqiao Hospital of Chongqing 20
Testing effectiveness (Phase 2)Ended earlyNCT05588440
What this trial is testing

A Clinical Study of ONCT-808 in Subjects With Relapsed or Refractory B-Cell Malignancies

Who this might be right for
Relapsed/Refractory Aggressive B-Cell Malignancies
Oncternal Therapeutics, Inc 9
Early research (Phase 1)Looking for participantsNCT05672147
What this trial is testing

CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaRecurrent Adult Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia+1 more
City of Hope Medical Center 27
Not applicableLooking for participantsNCT04981119
What this trial is testing

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

Who this might be right for
Solid Tumor, AdultColorectal CancerNon Small Cell Lung Cancer+14 more
A2 Biotherapeutics Inc. 200
Early research (Phase 1)Looking for participantsNCT06196294
What this trial is testing

GPC3/Mesothelin-CAR-γδT Cells Against Cancers

Who this might be right for
Pancreas CancerLung CancerLiver Cancer+3 more
Second Affiliated Hospital of Guangzhou Medical University 30
Testing effectiveness (Phase 2)UnknownNCT02134262
What this trial is testing

Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes

Who this might be right for
Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Jichi Medical University 18
Early research (Phase 1)Active Not RecruitingNCT01683279
What this trial is testing

A Pediatric Trial of Genetically Modified Autologous T Cells Directed Against CD19 for Relapsed CD19+ Acute Lymphoblastic Leukemia

Who this might be right for
B Cell Leukemia
Seattle Children's Hospital 6
Early research (Phase 1)Active Not RecruitingNCT03500991
What this trial is testing

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

Who this might be right for
Central Nervous System Tumor, PediatricGliomaEpendymoma+6 more
Seattle Children's Hospital 10
Testing effectiveness (Phase 2)Looking for participantsNCT06538012
What this trial is testing

TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer

Who this might be right for
Lung CancerLung Cancer MetastaticLung Cancer, Non-small Cell+1 more
Essen Biotech 85
Early research (Phase 1)Looking for participantsNCT03198052
What this trial is testing

GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers

Who this might be right for
Lung CancerCancerImmunotherapy+1 more
Second Affiliated Hospital of Guangzhou Medical University 30
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