Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “CBS Deficiency”

10 trials

Showing 10 of 10 results

Not applicableLooking for participantsNCT06556615
What this trial is testing

Health Related Quality of Life (HrQoL) in Classical Homocystinuria (CBS Deficiency)

Who this might be right for
Homocystinuria
University Children's Hospital, Zurich 80
Testing effectiveness (Phase 2)Ended earlyNCT05154890
What this trial is testing

A Multiple Ascending Dose Study of ACN00177 (Pegtarviliase) in Subjects With CBS Deficiency

Who this might be right for
Homocystinuria Due to Cystathionine Beta-Synthase Deficiency
Aeglea Biotherapeutics 13
Testing effectiveness (Phase 2)Temporarily pausedNCT04015557
What this trial is testing

Effect of Acetaminophen and N-Acetylcysteine on Liver Metabolism on Homocystinuria

Who this might be right for
CBS Deficiency
Hospital de Clinicas de Porto Alegre 10
Large-scale testing (Phase 3)Active Not RecruitingNCT06247085
What this trial is testing

Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment

Who this might be right for
Homocystinuria
Travere Therapeutics, Inc. 70
Not applicableLooking for participantsNCT02998710
What this trial is testing

Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)

Who this might be right for
Homocystinuria Due to CBS Deficiency
Travere Therapeutics, Inc. 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT03406611
What this trial is testing

Pegtibatinase As an Enzyme Therapy for Patients with Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (COMPOSE)

Who this might be right for
Homocystinuria
Travere Therapeutics, Inc. 32
Not applicableEnrolling By InvitationNCT06545305
What this trial is testing

Incidence and Risk Factors of Ocular Complications Among Patients With Homocystinuria

Who this might be right for
Complications
King Fahad Armed Forces Hospital 6
Large-scale testing (Phase 3)Enrolling By InvitationNCT06431893
What this trial is testing

Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

Who this might be right for
Homocystinuria
Travere Therapeutics, Inc. 100
Not applicableUnknownNCT04578145
What this trial is testing

Community Based Screening for HIV Self Testing in FSW in 23 Priority Districts in Indonesia

Who this might be right for
Human Immunodeficiency Virus (HIV)
Kerti Praja Foundation 1,522
Not applicableStudy completedNCT04287881
What this trial is testing

Methylenetetrahydrofolate Reductase Deficiency in Ischemic Stroke

Who this might be right for
Hyperhomocysteinemia, Thrombotic, Cbs-RelatedIschemic StrokeEpilepsy
Istanbul Medeniyet University 32

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation