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Results for “CCND1 Gene Amplification”

4 trials

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Showing 4 of 4 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04439201
What this trial is testing

Testing Palbociclib (PD-0332991) as a Potential Targeted Treatment in Cancers With CCND1, 2, 3 Amplification (MATCH-Subprotocol Z1B)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+2 more
National Cancer Institute (NCI) 40
Early research (Phase 1)Study completedNCT02508467
What this trial is testing

Fisogatinib (BLU-554) in Patients With Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma (HCC)
Blueprint Medicines Corporation 146
Testing effectiveness (Phase 2)Study completedNCT03356223
What this trial is testing

Evaluation of ABEMACICLIB Monotherapy in Patients With Locally Advanced/Metastatic Head and Neck Cancer After Failure of Platinum and Cetuximab or Anti-EGFR-based Therapy and Harboring an Homozygous Deletion of CDKN2A, and/or an Amplification of CCND1 and/or of CDK6

Who this might be right for
Head and Neck CancerAdvanced CancerMetastatic Cancer
Centre Leon Berard 25
Large-scale testing (Phase 3)Study completedNCT02785939
What this trial is testing

Lung-MAP: Palbociclib as Second-Line Therapy in Treating Cell Cycle Gene Alteration Positive Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Who this might be right for
CCND1 Gene AmplificationCCND2 Gene AmplificationCCND3 Gene Amplification+3 more
SWOG Cancer Research Network 53