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Results for “CD19+ Leukemia, B-Cell”

382 trials

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Showing 20 of 382 results

Early research (Phase 1)Ended earlyNCT03103971
What this trial is testing

HuJCAR014 CAR-T Cells in Treating Adult Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia

Who this might be right for
Recurrent Adult Acute Lymphoblastic LeukemiaRecurrent B-Cell Non-Hodgkin LymphomaRecurrent Diffuse Large B-Cell Lymphoma+14 more
Fred Hutchinson Cancer Center 55
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06631040
What this trial is testing

Cell Therapy with Anti-CD19 CAR-NK Cells in Patients with Relapsed or Resistant B-ALL

Who this might be right for
Acute Lymphocytic Leukemia in Relapse
Shahid Beheshti University of Medical Sciences 10
Early research (Phase 1)Active Not RecruitingNCT01430390
What this trial is testing

In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell Malignancies

Who this might be right for
Acute Lymphocytic LeukemiaLymphoma
Memorial Sloan Kettering Cancer Center 19
Testing effectiveness (Phase 2)UnknownNCT04714593
What this trial is testing

Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory Acute B Lymphocytic Leukemia

Who this might be right for
Acute Lymphocytic Leukemia， B-Cell
Shanxi Province Cancer Hospital 24
Early research (Phase 1)Active Not RecruitingNCT02935257
What this trial is testing

Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19

Who this might be right for
Leukemia, Lymphoblastic, Acute, Lymphoma
University College, London 72
Very early researchEnded earlyNCT04034446
What this trial is testing

CD19-CD22 Chimeric Antigen Receptor T (CAR-T) Cell for Treatment of B Cell Acute Lymphoblastic Leukemia (B-ALL)

Who this might be right for
Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
Institute of Hematology & Blood Diseases Hospital, China 2
Testing effectiveness (Phase 2)Looking for participantsNCT05643742
What this trial is testing

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

Who this might be right for
B-cell LymphomaNon-Hodgkin LymphomaB-cell Malignancy+5 more
CRISPR Therapeutics AG 120
Testing effectiveness (Phase 2)Looking for participantsNCT05674175
What this trial is testing

Co-administration of CART22-65s and huCART19 for B-ALL

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaB Lineage Lymphoblastic Lymphoma
Stephan Grupp MD PhD 93
Early research (Phase 1)Ended earlyNCT07556757
What this trial is testing

A Safety and Efficacy Study of CD-19 t-haNK in Patients With B-cell Acute Lymphoblastic Leukemia

Who this might be right for
B-ALLLeukemia
ImmunityBio, Inc. 4
Early research (Phase 1)UnknownNCT05210907
What this trial is testing

Clinical Study of Hospital-manufactured CD19 CAR-T in Children and Adolescents With Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Seoul National University Hospital 5
Early research (Phase 1)UnknownNCT03298828
What this trial is testing

CD19 CAR and PD-1 Knockout Engineered T Cells for CD19 Positive Malignant B-cell Derived Leukemia and Lymphoma

Who this might be right for
Acute Lymphoblastic LeukemiaBurkitt Lymphoma
Third Military Medical University 30
Early research (Phase 1)Ended earlyNCT06343376
What this trial is testing

Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies

Who this might be right for
Recurrent Chronic Lymphocytic LeukemiaRecurrent Diffuse Large B-Cell LymphomaRecurrent Follicular Lymphoma+11 more
Roswell Park Cancer Institute 1
Early research (Phase 1)Looking for participantsNCT06326008
What this trial is testing

Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia, in Relapse
Beijing GoBroad Hospital 48
Early research (Phase 1)Study completedNCT01786135
What this trial is testing

A Safety Study of SGN-CD19A for B-Cell Lymphoma

Who this might be right for
Burkitt LymphomaLymphoma, FollicularLymphoma, Large B-Cell, Diffuse+2 more
Seagen Inc. 64
Testing effectiveness (Phase 2)UnknownNCT02965092
What this trial is testing

CD19 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy in Treating Patients With B-cell Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaB Cell Lymphoma
Wuhan Sian Medical Technology Co., Ltd 80
Testing effectiveness (Phase 2)Study completedNCT01475058
What this trial is testing

CD19 CAR T Cells for B Cell Malignancies After Allogeneic Transplant

Who this might be right for
Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic LeukemiaPhiladelphia Chromosome Positive Adult Precursor Acute Lymphoblastic LeukemiaRecurrent Adult Acute Lymphoblastic Leukemia+4 more
Fred Hutchinson Cancer Center 1
Early research (Phase 1)UnknownNCT06056752
What this trial is testing

QH103 Cell Injection for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Anhui Provincial Hospital 10
Not applicableStudy completedNCT05784415
What this trial is testing

Observational Study of People Living With HIV Treated With CD19-directed CAR T Cell

Who this might be right for
LeukemiaLeukemia, LymphoblasticLymphoma, Large B-Cell, Diffuse+7 more
AIDS Malignancy Consortium 30
Testing effectiveness (Phase 2)Ended earlyNCT04809467
What this trial is testing

A Study Evaluating Safety, PK, and Efficacy of Tafasitamab and Parsaclisib in Participants With Relapsed/Refractory Non Hodgkin Lymphoma (R/R NHL) or Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
Chronic Lymphocytic LeukemiaNon Hodgkin Lymphoma
Incyte Corporation 54
Early research (Phase 1)Study completedNCT03751709
What this trial is testing

Blinatumomab Plus HLA-Mismatched Cellular Therapy for Relapsed/Refractory CD19+ ALL

Who this might be right for
B-Cell Acute Lymphoblastic LeukaemiaALL, AdultB-ALL
Cedars-Sinai Medical Center 22
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