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Results for “CD19+ Relapse/Refractory B-ALL”

193 trials

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Showing 20 of 193 results

Early research (Phase 1)Ended earlyNCT03103971
What this trial is testing

HuJCAR014 CAR-T Cells in Treating Adult Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia

Who this might be right for
Recurrent Adult Acute Lymphoblastic LeukemiaRecurrent B-Cell Non-Hodgkin LymphomaRecurrent Diffuse Large B-Cell Lymphoma+14 more
Fred Hutchinson Cancer Center 55
Testing effectiveness (Phase 2)UnknownNCT04714593
What this trial is testing

Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory Acute B Lymphocytic Leukemia

Who this might be right for
Acute Lymphocytic Leukemia, B-Cell
Shanxi Province Cancer Hospital 24
Very early researchEnded earlyNCT04034446
What this trial is testing

CD19-CD22 Chimeric Antigen Receptor T (CAR-T) Cell for Treatment of B Cell Acute Lymphoblastic Leukemia (B-ALL)

Who this might be right for
Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
Institute of Hematology & Blood Diseases Hospital, China 2
Testing effectiveness (Phase 2)Looking for participantsNCT05674175
What this trial is testing

Co-administration of CART22-65s and huCART19 for B-ALL

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaB Lineage Lymphoblastic Lymphoma
Stephan Grupp MD PhD 93
Early research (Phase 1)UnknownNCT05210907
What this trial is testing

Clinical Study of Hospital-manufactured CD19 CAR-T in Children and Adolescents With Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Seoul National University Hospital 5
Early research (Phase 1)Looking for participantsNCT06326008
What this trial is testing

Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia, in Relapse
Beijing GoBroad Hospital 48
Early research (Phase 1)Study completedNCT01786135
What this trial is testing

A Safety Study of SGN-CD19A for B-Cell Lymphoma

Who this might be right for
Burkitt LymphomaLymphoma, FollicularLymphoma, Large B-Cell, Diffuse+2 more
Seagen Inc. 64
Testing effectiveness (Phase 2)UnknownNCT02965092
What this trial is testing

CD19 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy in Treating Patients With B-cell Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaB Cell Lymphoma
Wuhan Sian Medical Technology Co., Ltd 80
Early research (Phase 1)UnknownNCT06056752
What this trial is testing

QH103 Cell Injection for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Anhui Provincial Hospital 10
Early research (Phase 1)Study completedNCT03751709
What this trial is testing

Blinatumomab Plus HLA-Mismatched Cellular Therapy for Relapsed/Refractory CD19+ ALL

Who this might be right for
B-Cell Acute Lymphoblastic LeukaemiaALL, AdultB-ALL
Cedars-Sinai Medical Center 22
Very early researchUnknownNCT03407859
What this trial is testing

Sequential Treatment With CD20/CD22/CD10-CART After CD19-CART Treatment Base on MRD in Relapsed/Refractory B-ALL

Who this might be right for
Therapy Related Leukemia
Zhujiang Hospital 100
Early research (Phase 1)Study completedNCT05563545
What this trial is testing

Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Shanghai Simnova Biotechnology Co.,Ltd. 2
Testing effectiveness (Phase 2)UnknownNCT03191773
What this trial is testing

Anti-CD19 CAR-T Cell Immunotherapy for Refractory /Relapsed B Cell Malignancies

Who this might be right for
Acute Lymphocytic LeukemiaChronic Lymphocytic LeukemiaLymphoma
Second Affiliated Hospital of Guangzhou Medical University 100
Very early researchUnknownNCT06393335
What this trial is testing

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Who this might be right for
Acute Lymphoblastic LeukemiaNon-hodgkin Lymphoma
The Children's Hospital of Zhejiang University School of Medicine 36
Not applicableTemporarily pausedNCT03229876
What this trial is testing

Safety and Efficacy Evaluation of CD19-UCART

Who this might be right for
Acute Lymphoblastic Leukemia (ALL)Non Hodgkin Lymphoma (NHL)
Bioray Laboratories 20
Early research (Phase 1)Active Not RecruitingNCT02879695
What this trial is testing

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute LeukemiaRefractory B Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 28
Not applicableLooking for participantsNCT06355739
What this trial is testing

CD19-targeted CAR T Cell Autotransfusion for the Treatment of Recurrent/Refractory B-cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in Children With CD19+

Who this might be right for
B Lymphocytic LeukemiaB Lymphoblastic Lymphoma
Zhu Xiaofan 60
Not applicableEnded earlyNCT03050190
What this trial is testing

A Phase I/II Multiple Center Trial of 4SCAR19 Cells in the Treatment of Relapsed and Refractory B Cell Malignancies

Who this might be right for
B-cell Malignancies
Shenzhen Geno-Immune Medical Institute 200
Early research (Phase 1)Study completedNCT02906371
What this trial is testing

Study of the Tocilizumab Optimization Timing for CART19 Associated Cytokine Release Syndrome

Who this might be right for
Lymphoblastic Leukemia, Acute, Childhood
University of Pennsylvania 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT03919240
What this trial is testing

CAR-T Cell Therapy Targeting to CD19 for R/R ALL

Who this might be right for
Acute Lymphoblastic Leukemia With Failed Remission
The First Affiliated Hospital of Soochow University 196
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