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Results for “CD19+ Relapse/Refractory B-ALL”

187 trials

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Showing 20 of 187 results

Early research (Phase 1)Looking for participantsNCT06445803
What this trial is testing

CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia With Failed RemissionB-cell Lymphoma Refractory+1 more
Rong Tao 48
Early research (Phase 1)UnknownNCT05223686
What this trial is testing

To Evaluate the Safety and Tolerability of Human CD19-CD22 Targeted T Cells Injection for Subjects With R/R B-ALL.

Who this might be right for
Acute Lymphoblastic Leukemia
Hrain Biotechnology Co., Ltd. 18
Not applicableLooking for participantsNCT06961669
What this trial is testing

Intravenous Autologous CD19 CAR-T Cells for R/ R MM, B-ALL, and B-Cell Lymphoma

Who this might be right for
Lymphoblastic LeukemiaRelapsed or Refractory Multiple Myeloma (RRMM)
Anhui Provincial Hospital 18
Early research (Phase 1)Ended earlyNCT05292898
What this trial is testing

A Triple-targeted Cell Preparation Targeting CD19/CD20/CD22 in Patients With Relapsed/Refractory B-cell Acute Lymphocytic Leukemia

Who this might be right for
Acute Lymphocytic Leukemia
Institute of Hematology & Blood Diseases Hospital, China 10
Early research (Phase 1)UnknownNCT04154709
What this trial is testing

CTA101 UCAR-T Cell Injection for Treatment of Relapsed or Refractory CD19+ B-cell Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Kai Lin Xu; Jun Nian Zheng 15
Early research (Phase 1)Not Yet RecruitingNCT07491263
What this trial is testing

Clinical Study of Universal CD19 CAR-γδ T Cell Infusion in the Treatment of Relapsed/Refractory Acute B Lymphoblastic Leukemia

Who this might be right for
Relapsed/Refractory CD19-positive B-ALL
Fujian Medical University 6
Testing effectiveness (Phase 2)Looking for participantsNCT03676504
What this trial is testing

Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR

Who this might be right for
Acute Lymphoblastic Leukemia, AdultAcute Lymphoblastic Leukemia, PediatricChronic Lymphocytic Leukemia+3 more
University Hospital Heidelberg 68
Early research (Phase 1)Active Not RecruitingNCT03853616
What this trial is testing

MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM)

Who this might be right for
Acute Lymphoblastic Leukemia RecurrentB-cell Lymphoma RecurrentB-cell Lymphoma Refractory+2 more
Miltenyi Biomedicine GmbH 48
Testing effectiveness (Phase 2)UnknownNCT03902197
What this trial is testing

CD19 hsCAR-T for Refractory/Relapsed CD19+ B-ALL Patients

Who this might be right for
Acute Lymphoblastic Leukemia
Xuanwu Hospital, Beijing 50
Very early researchLooking for participantsNCT04227015
What this trial is testing

CTA101 UCAR-T Cell Injection in Patients With Relapsed or Refractory CD19+ B-line Hematological Malignancy

Who this might be right for
Acute Lymphoblastic LeukemiaNon-hodgkin Lymphoma
He Huang 72
Early research (Phase 1)Not Yet RecruitingNCT07043218
What this trial is testing

A Clinical Study Exploring Universal CAR-T Cell in Patients With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Shanghai Tongji Hospital, Tongji University School of Medicine 36
Testing effectiveness (Phase 2)Study completedNCT01865617
What this trial is testing

Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia

Who this might be right for
CD19-Positive Neoplastic Cells PresentRecurrent Adult Acute Lymphoblastic LeukemiaRecurrent Chronic Lymphocytic Leukemia+10 more
Fred Hutchinson Cancer Center 204
Early research (Phase 1)Looking for participantsNCT07078929
What this trial is testing

Clinical Trial of CMD63 Chimeric Antigen Receptor T-cell (CAR T-cell) in Children With Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Relapse B Acute Lymphoblastic LeukemiaRefactory Childhood Acute Lymphoblastic Leukemia
Chulalongkorn University 16
Testing effectiveness (Phase 2)Looking for participantsNCT05674175
What this trial is testing

Co-administration of CART22-65s and huCART19 for B-ALL

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaB Lineage Lymphoblastic Lymphoma
Stephan Grupp MD PhD 93
Early research (Phase 1)WithdrawnNCT05037669
What this trial is testing

Programmed Allogeneic CRISPR-edited T Cells Engineered to Express Anti-CD19 Chimeric Antigen Receptor (PACE CART19) in Patients With Relapsed Or Refractory CD19+ Leukemia and Lymphoma

Who this might be right for
Acute Lymphoblastic LeukemiaChronic Lymphocytic LeukemiaNon Hodgkin Lymphoma
University of Pennsylvania
Testing effectiveness (Phase 2)Study completedNCT03056339
What this trial is testing

Umbilical & Cord Blood (CB) Derived CAR-Engineered NK Cells for B Lymphoid Malignancies

Who this might be right for
B-Lymphoid MalignanciesAcute Lymphocytic LeukemiaChronic Lymphocytic Leukemia+1 more
M.D. Anderson Cancer Center 49
Early research (Phase 1)Study completedNCT06027957
What this trial is testing

CD19 CAR T-Cell Therapy for R/R Non-Hodgkin Lymphoma and Acute Lymphoblastic Leukemia

Who this might be right for
B-Cell Non Hodgkin LymphomaB-Cell Acute Lymphoblastic Leukemia
Vinmec Research Institute of Stem Cell and Gene Technology 18
Early research (Phase 1)Study completedNCT02746952
What this trial is testing

Dose Escalation Study of UCART19 in Adult Patients With Relapsed / Refractory B-cell Acute Lymphoblastic Leukaemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Institut de Recherches Internationales Servier 25
Early research (Phase 1)UnknownNCT02924753
What this trial is testing

The Safety and Efficacy of CART-19 Cells in B-cell Acute Lymphoblastic Leukemia (B-ALL).

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Henan Cancer Hospital 20
Early research (Phase 1)WithdrawnNCT04094766
What this trial is testing

Safety and Efficacy of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy in R/R Acute B Lymphoblastic Leukemia

Who this might be right for
Refractory B Acute Lymphoblastic LeukemiaRelapse B Acute Lymphoblastic Leukemia
Second Affiliated Hospital of Xi'an Jiaotong University
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