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Results for “CD19-directed CAR T-cell Therapy”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)UnknownNCT05429905
What this trial is testing

Dual Anti-CD22/CD19 Chimeric Antigen Receptor-directed T Cells (CART2219.1) for Relapsed Refractory B-Lineage Leukaemia

Who this might be right for
Lymphoblastic LeukemiaLymphoblastic Leukemia, Acute, ChildhoodLymphoblastic Leukemia in Children+2 more
KK Women's and Children's Hospital 48
Large-scale testing (Phase 3)Ended earlyNCT05664217
What this trial is testing

NKTR-255 vs Placebo Following CD19-directed CAR-T Therapy in Patients With Relapsed/Refractory Large B-cell Lymphoma

Who this might be right for
Non-Hodgkin LymphomaRelapsed/Refractory Diffuse Large B-cell Lymphoma
Nektar Therapeutics 15
Early research (Phase 1)Study completedNCT04655677
What this trial is testing

C-CAR039 Treatment in Subjects With r/r NHL SubjectsNon-Hodgkin's Lymphoma

Who this might be right for
B-cell Non-Hodgkin's Lymphoma
Peking Union Medical College Hospital 10
Testing effectiveness (Phase 2)Looking for participantsNCT06839976
What this trial is testing

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

Who this might be right for
SLESystemic Lupus Erythematosus (SLE)CAR T Cell+4 more
Children's Hospital of Philadelphia 24
Early research (Phase 1)Not Yet RecruitingNCT07725406
What this trial is testing

Low-Dose TBI Plus CAR T-Cell Therapy for Relapsed/Refractory DLBCL and Multiple Myeloma

Who this might be right for
Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)Relapsed or Refractory Multiple Myeloma (MM)
Weill Medical College of Cornell University 32
Early research (Phase 1)Looking for participantsNCT06522932
What this trial is testing

PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy

Who this might be right for
Non Hodgkin Lymphoma
Michael Randall 32
Early research (Phase 1)Looking for participantsNCT05535855
What this trial is testing

UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1

Who this might be right for
Acute Lymphoid LeukemiaAcute Lymphoblastic Leukemia
University of Colorado, Denver 29
Not applicableStudy completedNCT05784415
What this trial is testing

Observational Study of People Living With HIV Treated With CD19-directed CAR T Cell

Who this might be right for
LeukemiaLeukemia, LymphoblasticLymphoma, Large B-Cell, Diffuse+7 more
AIDS Malignancy Consortium 30
Testing effectiveness (Phase 2)Looking for participantsNCT05480449
What this trial is testing

Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)

Who this might be right for
B Cell Acute Lymphoblastic Leukemia (B-ALL)B Lineage Lymphoblastic Lymphoma
Stephan Grupp MD PhD 115
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07569965
What this trial is testing

Frontline Risk-Adapted Optimization of Novel Targeted Immunotherapy Evaluation in High-Risk MCL

Who this might be right for
Mantle Cell Lymphoma (MCL)
Miltenyi Biomedicine GmbH 52
Early research (Phase 1)Active Not RecruitingNCT01683279
What this trial is testing

A Pediatric Trial of Genetically Modified Autologous T Cells Directed Against CD19 for Relapsed CD19+ Acute Lymphoblastic Leukemia

Who this might be right for
B Cell Leukemia
Seattle Children's Hospital 6
Early research (Phase 1)Looking for participantsNCT07532525
What this trial is testing

Pomalidomide After CAR T-cell Therapy for the Treatment of Relapsed or Refractory CD19+ B-cell Leukemia or Lymphoma

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent B-Cell Non-Hodgkin LymphomaRefractory B Acute Lymphoblastic Leukemia+1 more
University of Michigan Rogel Cancer Center 12
Testing effectiveness (Phase 2)Looking for participantsNCT05850234
What this trial is testing

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

Who this might be right for
Relapsed/Refractory Multiple Myeloma
AstraZeneca 232
Early research (Phase 1)Study completedNCT04696432
What this trial is testing

C-CAR039 Treatment in Subjects With r/r NHL SubjectsNon-Hodgkin's Lymphoma

Who this might be right for
Non-Hodgkin's B-cell Lymphoma
Tianjin Medical University Cancer Institute and Hospital 7
Early research (Phase 1)Active Not RecruitingNCT06294236
What this trial is testing

Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM)

Who this might be right for
Lupus ErythematosusSystemic Lupus ErythematosusSLE (Systemic Lupus)+3 more
Sana Biotechnology 7
Testing effectiveness (Phase 2)WithdrawnNCT06009107
What this trial is testing

HY004 Treatment in Adult Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r B-ALL)

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Juventas Cell Therapy Ltd.
Testing effectiveness (Phase 2)Looking for participantsNCT07003295
What this trial is testing

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

Who this might be right for
Recurrent Mantle Cell LymphomaRefractory Mantle Cell Lymphoma
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)Temporarily pausedNCT07098364
What this trial is testing

ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Recurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedRecurrent Grade 3b Follicular Lymphoma+9 more
Fred Hutchinson Cancer Center 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT05404048
What this trial is testing

PD-L1 PET-imaging During CAR T-cell Therapy

Who this might be right for
Large B-cell Lymphoma
University Medical Center Groningen 20
Early research (Phase 1)Looking for participantsNCT07073547
What this trial is testing

A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

Who this might be right for
Multiple Myeloma
AstraZeneca 40
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