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Results for “CDK4/6 Inhibitors”

92 trials

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Showing 20 of 92 results

Large-scale testing (Phase 3)Active Not RecruitingNCT02246621
What this trial is testing

Nonsteroidal Aromatase Inhibitors Plus Abemaciclib (LY2835219) in Postmenopausal Women With Breast Cancer

Who this might be right for
Breast Cancer
Eli Lilly and Company 493
Not applicableLooking for participantsNCT04526587
What this trial is testing

Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaPrognostic Stage IV Breast Cancer AJCC v8
Roswell Park Cancer Institute 700
Not applicableStudy completedNCT05770713
What this trial is testing

A Real-life Study to Learn About the Use and Effects of the CDK4/6 Inhibitors in Canadian Patients With Breast Cancer.

Who this might be right for
Breast Cancer
Pfizer 48
Not applicableLooking for participantsNCT07617025
What this trial is testing

Prognostic and Predictive Role of Intrinsic Molecular Subtypes in BRCA-associated Breast Cancer

Who this might be right for
Breast Cancer
Angela Toss 100
Not applicableActive Not RecruitingNCT06926088
What this trial is testing

Impact of BMI on CDK4/6 Inhibitors Efficacy and Safety in Advanced Breast Cancer

Who this might be right for
Advanced Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 500
Not applicableStudy completedNCT07498413
What this trial is testing

Epidemiology and Treatment of HR+/HER2- Breast Cancer in England

Who this might be right for
Breast Cancer
Novartis Pharmaceuticals 218,677
Not applicableLooking for participantsNCT06666439
What this trial is testing

Longitudinal Tumor Burden Quantification Using Circulating Tumor DNA in Metastatic Lobular Breast Cancer

Who this might be right for
Metastatic Invasive Lobular Carcinoma (mILC)
Julia Foldi 20
Testing effectiveness (Phase 2)Looking for participantsNCT06947811
What this trial is testing

Almonertinib Combined With Palbociclib in Patients With Advanced Solid Tumors Harboring KRAS Mutations

Who this might be right for
EGFR Tyrosine Kinase Inhibitors Plus Cyclin-dependent Kinase 4/6 Inhibitor
Sun Yat-sen University 71
Not applicableUnknownNCT06243432
What this trial is testing

Estrogen Receptors and HER2 Levels' Expression in Luminal Metastatic Breast Cancer

Who this might be right for
Advanced Breast Carcinoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 600
Not applicableStudy completedNCT05153135
What this trial is testing

Description of Treatment Patterns and Description and Comparison of Healthcare Resource Utilization and Costs of Women With Metastatic HR+/HER2- Breast Cancer Treated With CDK4/6 Inhibitors

Who this might be right for
Metastatic Breast Cancer
Novartis Pharmaceuticals 4,320
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07173556
What this trial is testing

A Phase Ib/II Study of QLC1401 Combined With CDK4/6 or mTOR Inhibitors in ER+/HER2- Advanced Breast Cancer

Who this might be right for
Advanced Breast Cancer
Qilu Pharmaceutical Co., Ltd. 96
Not applicableStudy completedNCT06367335
What this trial is testing

Characteristics and Predictors of Liver Injury in Cyclin-dependent Kinase Inhibitors 4/6 (CDK4/6)-Treated Patients With Advanced Breast Cancer

Who this might be right for
DILI
University of Milano Bicocca 128
Testing effectiveness (Phase 2)Study completedNCT03839823
What this trial is testing

Study to Compare the Combination of Ribociclib Plus Goserelin Acetate With Hormonal Therapy Versus Combination Chemotherapy in Premenopausal or Perimenopausal Patients With Advanced or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Novartis Pharmaceuticals 222
Early research (Phase 1)Looking for participantsNCT06139107
What this trial is testing

RADIANT: Pre-op Radiation With Abemaciclib and Letrozole

Who this might be right for
Breast Cancer
Mridula George, MD 15
Testing effectiveness (Phase 2)Study completedNCT04010357
What this trial is testing

Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC

Who this might be right for
Small-cell Lung CancerLarge Cell Neuroendocrine Carcinoma of the LungExtrapulmonary Small Cell Carcinoma
Case Comprehensive Cancer Center 14
Not applicableUnknownNCT05814224
What this trial is testing

Monitoring luminAl Breast Cancer Through the Evaluation of Mutational and epiGeNEtic alteraTIons of Circulating ESR1 DNA

Who this might be right for
Hormone Receptor Positive Breast CarcinomaBreast NeoplasmsNeoplasms, Breast+4 more
Centro di Riferimento Oncologico - Aviano 164
Not applicableLooking for participantsNCT07407439
What this trial is testing

Real-world Studies of CDK4/6 Inhibitors

Who this might be right for
Breast Cancer
Tianjin Medical University Cancer Institute and Hospital 245
Not applicableStudy completedNCT07647042
What this trial is testing

A Real-World Study of Early Breast Cancer Patients Eligible for Treatment With CDK4/6 Inhibitors

Who this might be right for
Breast Cancer
Novartis Pharmaceuticals 750
Large-scale testing (Phase 3)Looking for participantsNCT07544056
What this trial is testing

BEBT-209 Plus Chemotherapy in Patients With Locally Advanced or Metastatic Triple-Negative Breast Cancer

Who this might be right for
Locally Advanced Triple-negative Breast CancerMetastatic Triple-negative Breast Cancer
BeBetter Med Inc 446
Large-scale testing (Phase 3)Not Yet RecruitingNCT07382687
What this trial is testing

Famitinib Combined With SHR-A1811, Versus SHR-A1811 for CDK4/6 Inhibitors-resistent Advanced HR+/HER2- Breast Cancer With SNF4 Subtype

Who this might be right for
Breast Cancer
Fudan University 248
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