Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “CDKL5 Deficiency Disease”

19 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 19 of 19 results

Not applicableStudy completedNCT02738281
What this trial is testing

Natural History of Rett Syndrome & Related Disorders

Who this might be right for
Rett SyndromeMECP2 Duplication dIsorderCDKL5 Disorder+1 more
University of Alabama at Birmingham 1,044
Large-scale testing (Phase 3)Not Yet RecruitingNCT05249556
What this trial is testing

Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old

Who this might be right for
CDKL5 Deficiency Disorder
Immedica Pharma AB 20
Not applicableLooking for participantsNCT05558371
What this trial is testing

International CDKL5 Clinical Research Network

Who this might be right for
CDKL5CDKL5 Deficiency DisorderCDD
University of Colorado, Denver 1,000
Not applicableStudy completedNCT06663163
What this trial is testing

The Association Between Fever and CDKL5 Deficiency Disorder: a Nationwide Survey

Who this might be right for
CDKL5 Deficiency Disorder
Xuanwu Hospital, Beijing 131
Not applicableActive Not RecruitingNCT05373719
What this trial is testing

Observational Study in Patients With Cyclin-dependent Kinase-like 5 Deficiency Disorder

Who this might be right for
Cyclin-Dependent Kinase-Like 5 Deficiency Disorder
Loulou Foundation 112
Testing effectiveness (Phase 2)Study completedNCT03650452
What this trial is testing

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies

Who this might be right for
EpilepsyDravet SyndromeLennox-Gastaut Syndrome
Takeda 141
Testing effectiveness (Phase 2)Study completedNCT03694275
What this trial is testing

A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)

Who this might be right for
15q Duplication SyndromeCDKL5 Deficiency Disease
Takeda 20
Testing effectiveness (Phase 2)Study completedNCT05364021
What this trial is testing

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox Gastaut Syndrome
Longboard Pharmaceuticals 52
Not applicableStudy completedNCT06447675
What this trial is testing

Efficacy and Safety Evaluation of Hyperthermic Baths in the Treatment of Seizures in CDKL5 Deficiency Disorder

Who this might be right for
CDKL5 Deficiency Disorder
Xuanwu Hospital, Beijing 8
Not applicableLooking for participantsNCT06448663
What this trial is testing

Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD)

Who this might be right for
CDKL5
University of Milan 20
Testing effectiveness (Phase 2)Study completedNCT05626634
What this trial is testing

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox-Gastaut Syndrome
Longboard Pharmaceuticals 41
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Large-scale testing (Phase 3)Active Not RecruitingNCT05064878
What this trial is testing

Investigate the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder

Who this might be right for
CDKL5 Deficiency DisorderGeneralized Tonic Clonic SeizureEpileptic Spasm+1 more
Zogenix, Inc. 87
Not applicableNo Longer AvailableNCT04678479
What this trial is testing

Ganaxolone Expanded Access Program Compassionate Use

Who this might be right for
CDKL5 Disorder
Marinus Pharmaceuticals
Not applicableLooking for participantsNCT04486768
What this trial is testing

International CDKL5 Registry

Who this might be right for
CDKL5 Deficiency Disorder (CDD)
University of Pennsylvania 500
Not applicableAvailableNCT06149663
What this trial is testing

Intermediate-Size Expanded Access Protocol (EAP) for LP352

Who this might be right for
Dravet SyndromeLennox Gastaut SyndromeDevelopmental and Epileptic Encephalopathies
Longboard Pharmaceuticals
Testing effectiveness (Phase 2)Ended earlyNCT03635073
What this trial is testing

Soticlestat in Adults and Children With Rare Epilepsies

Who this might be right for
EpilepsyDravet Syndrome (DS)Lennox-Gastaut Syndrome (LGS)
Takeda 156
Testing effectiveness (Phase 2)Study completedNCT03861871
What this trial is testing

Fenfluramine in CDKL5 Deficiency Disorder (CDD)

Who this might be right for
CDD
NYU Langone Health 7
Large-scale testing (Phase 3)Study completedNCT03572933
What this trial is testing

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder

Who this might be right for
CDKL5 Deficiency Disorder
Marinus Pharmaceuticals 101