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Results for “CLDN18.2 Positive Solid Tumors”

21 trials

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Showing 20 of 21 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07460375
What this trial is testing

Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
LigaChem Biosciences, Inc. 191
Early research (Phase 1)Study completedNCT05199519
What this trial is testing

Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Preliminary Efficacy of IBI345

Who this might be right for
CLDN18.2 Positive Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd. 7
Early research (Phase 1)Looking for participantsNCT05857332
What this trial is testing

SG1906 for CLDN18.2-Positive Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Hangzhou Sumgen Biotech Co., Ltd. 60
Early research (Phase 1)UnknownNCT05472857
What this trial is testing

Clinical Study of CLDN18.2-targeting CAR T Cells in Advanced Solid Tumors With Positive CLDN18.2 Expression

Who this might be right for
Gastric CancerPancreatic CancerAdvanced Ovarian Carcinoma+1 more
Suzhou Immunofoco Biotechnology Co., Ltd 30
Early research (Phase 1)Looking for participantsNCT06084286
What this trial is testing

Dual-targeting CLDN18.2 and PD-L1 CAR-T for Patients with CLDN18.2-positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Sichuan University 29
Not applicableUnknownNCT05952375
What this trial is testing

Exploratory Clinical Trial on the Safety, Efficacy, and Pharmacokinetics of XKDCT086 (iPD-1-Claudin18.2-CAR-T) in Claudin 18.2 Positive Advanced Solid Malignant Tumors: a Single Center, Single Arm, Dose-increasing Trial

Who this might be right for
Gastric Cancer
The Affiliated Hospital of Qingdao University 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT05862324
What this trial is testing

TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3)

Who this might be right for
Metastatic Solid Tumor
Triumvira Immunologics, Inc. 113
Testing effectiveness (Phase 2)Looking for participantsNCT06038396
What this trial is testing

RC118 Plus Toripalimab / RC148 in Patients with Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 48
Early research (Phase 1)Looking for participantsNCT06350006
What this trial is testing

SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor

Who this might be right for
CLDN18.2-positive Advanced Solid Tumor
Shanghai Hengrui Pharmaceutical Co., Ltd. 924
Testing effectiveness (Phase 2)Looking for participantsNCT05205850
What this trial is testing

RC118 in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 135
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06446388
What this trial is testing

Study of QLS31905 and/or QL1706 Combination With Chemotherapy in the Advanced Malignant Solid Tumors

Who this might be right for
Advanced Solid Tumor
Qilu Pharmaceutical Co., Ltd. 360
Early research (Phase 1)Study completedNCT04400383
What this trial is testing

Clinical Trial to Evaluate AB011 Injection in Patients With CLDN18.2-positive Advanced Solid Tumors

Who this might be right for
Solid TumorGastric CancerPancreatic Adenocarcinoma
CARsgen Therapeutics Co., Ltd. 62
Testing effectiveness (Phase 2)Looking for participantsNCT07432295
What this trial is testing

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

Who this might be right for
Solid TumorAdvanced CancerMetastatic Cancer+3 more
I-Mab Biopharma US Limited 180
Testing effectiveness (Phase 2)Ended earlyNCT05008445
What this trial is testing

Study of LM-102 in Patients With Advance Solid Tumors

Who this might be right for
Advanced Solid Tumor
LaNova Medicines Development Co., Ltd. 11
Testing effectiveness (Phase 2)Study completedNCT05161390
What this trial is testing

Study of LM-302 in Patients With Advance Solid Tumors

Who this might be right for
Advanced Solid Tumor
LaNova Medicines Zhejiang Co., Ltd. 153
Testing effectiveness (Phase 2)Ended earlyNCT04683939
What this trial is testing

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors

Who this might be right for
Solid TumorGastric CancerGastroesophageal Junction Adenocarcinoma+5 more
BioNTech SE 13
Early research (Phase 1)UnknownNCT05837299
What this trial is testing

IMC008 for Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Changhai Hospital 18
Not applicableUnknownNCT04989010
What this trial is testing

Safety Study of 89Zr-Anti-CLDN18.2 mAbs PET Imaging in Patients With CLDN18.2 Positive Solid Tumors

Who this might be right for
Solid Tumor, Adult
Wuxi No. 4 People's Hospital 20
Early research (Phase 1)Ended earlyNCT04735796
What this trial is testing

Study of LM-102 in Subjects in Advanced Tumors

Who this might be right for
Advanced Solid Tumors
LaNova Medicines Limited 9
Testing effectiveness (Phase 2)UnknownNCT06041035
What this trial is testing

QLS31905 Combination Chemotherapy as First-Line Treatment in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Qilu Pharmaceutical Co., Ltd. 115
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