Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “COVID-19 (Severe Coronavirus Disease 2019)”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Not applicableStudy completedNCT04609462
What this trial is testing

High-Flow Nasal Cannula in Severe COVID-19 With Acute Hypoxemic Respiratory Failure.

Who this might be right for
Covid19Acute Hypoxemic Respiratory Failure
Fundacion Clinica Valle del Lili 199
Testing effectiveness (Phase 2)Ended earlyNCT04377659
What this trial is testing

Tocilizumab for Prevention of Respiratory Failure in Patients With Severe COVID-19 Infection

Who this might be right for
COVID-19
Memorial Sloan Kettering Cancer Center 9
Early research (Phase 1)Study completedNCT05870839
What this trial is testing

Study of VXCO-100, a SARS-CoV Candidate Vaccine in Healthy Adults in the United States

Who this might be right for
SARS-CoVSARS-CoV-2
Vaccine Company, Inc. 121
Early research (Phase 1)UnknownNCT05083000
What this trial is testing

Reducing Hypoxia in Patients With Coronavirus Disease (COVID-19) Using Topotecan With Standard of Care

Who this might be right for
COVID-19 Respiratory Infection
National University Hospital, Singapore 24
Large-scale testing (Phase 3)UnknownNCT04641481
What this trial is testing

An Efficacy and Safety Clinical Trial of an Investigational COVID-19 Vaccine (BBV152) in Adult Volunteers

Who this might be right for
Covid19SARS-CoV Infection
Bharat Biotech International Limited 25,800
Testing effectiveness (Phase 2)UnknownNCT04622865
What this trial is testing

Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19

Who this might be right for
SARS-CoV 2COVID-19Coronavirus Disease 2019
AB Science 200
Early research (Phase 1)Study completedNCT04646044
What this trial is testing

A Placebo Controlled Trial of Bempegaldesleukin (BEMPEG; NKTR-214) With Standard of Care in Patients With Mild COVID-19

Who this might be right for
Covid-19Coronavirus Disease 2019
Nektar Therapeutics 30
Not applicableStudy completedNCT04745611
What this trial is testing

Neurological and Neuropsychological Sequelae of COVID-19 Infection

Who this might be right for
COVID-19 Infection
Maastricht University 329
Large-scale testing (Phase 3)Ended earlyNCT04516811
What this trial is testing

Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19

Who this might be right for
COVID-19SARS-CoV-2 InfectionSevere Acute Respiratory Syndrome Coronavirus 2
South African National Blood Service 102
Large-scale testing (Phase 3)Ended earlyNCT04928430
What this trial is testing

Efficacy and Safety of XAV-19 for the Treatment of Moderate-to-severe COVID-19

Who this might be right for
COVID-19
Xenothera SAS 290
Post-approval studies (Phase 4)Study completedNCT04746365
What this trial is testing

Ivermectin Role in Covid-19 Clinical Trial

Who this might be right for
Covid19
Elaraby Hospital 300
Early research (Phase 1)Ended earlyNCT04652765
What this trial is testing

Camostat With Bicalutamide for COVID-19

Who this might be right for
Covid19SARS-CoV InfectionCoronavirus Infection
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 6
Testing effectiveness (Phase 2)Study completedNCT04530136
What this trial is testing

Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19

Who this might be right for
Confirmed Coronavirus Disease
Pharming Technologies B.V. 38
Large-scale testing (Phase 3)Ended earlyNCT04952519
What this trial is testing

Efficacy of Amantadine Treatment in COVID-19 Patients

Who this might be right for
Patients With Moderate or Severe COVID-19
Noblewell 193
Large-scale testing (Phase 3)Study completedNCT04380519
What this trial is testing

Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection (COVID-19)

Who this might be right for
COVID-19
R-Pharm International, LLC 372
Early research (Phase 1)Study completedNCT05844202
What this trial is testing

Safety, Tolerability and Immunogenicity of Alveavax-v1.2, a BA.2/Omicron-optimized, DNA Vaccine for COVID-19 Prevention

Who this might be right for
Sars-CoV-2 Infection
Alvea Holdings, LLC 130
Not applicableEnded earlyNCT04619719
What this trial is testing

Hyperbaric Oxygen for COVID-19 Patients With Moderate to Severe Hypoxemia

Who this might be right for
Covid19
Legacy Health System 27
Testing effectiveness (Phase 2)UnknownNCT04352465
What this trial is testing

Efficacy and Safety of MTX-loaded Nanoparticles to Treat Severe COVID-19 Patients

Who this might be right for
COVID-19
Azidus Brasil 42
Not applicableStudy completedNCT05104411
What this trial is testing

Rehabilitation in Severely Ill Inpatients With COVID-19

Who this might be right for
COVID-19
Seoul National University Bundang Hospital 37
Testing effectiveness (Phase 2)WithdrawnNCT04290871
What this trial is testing

Nitric Oxide Gas Inhalation for Severe Acute Respiratory Syndrome in COVID-19.

Who this might be right for
Coronavirus Covid-19 Infection Variant OmicronSARS (Severe Acute Respiratory Syndrome)
Xijing Hospital
Next Page