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Results for “CTLA-4”

354 trials

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Showing 20 of 354 results

Testing effectiveness (Phase 2)Looking for participantsNCT07290010
What this trial is testing

The Efficacy and Safety of Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy as the First-line Treatment for Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Hebei Medical University Fourth Hospital 25
Very early researchLooking for participantsNCT06248697
What this trial is testing

Exploratory Study of MSLN-CAR T Cells Secreting PD1/CTLA-4 Nanoantibody for the Treatment of Advanced Solid Tumors

Who this might be right for
Solid Tumor
Shanghai Cell Therapy Group Co.,Ltd 16
Early research (Phase 1)Study completedNCT04945421
What this trial is testing

IBI310 in Combination With Siltilimab in Subjects With Anti-PD-1/PD-L1 Resistance R/M NPC

Who this might be right for
NPC
Innovent Biologics (Suzhou) Co. Ltd. 30
Testing effectiveness (Phase 2)Ended earlyNCT03457142
What this trial is testing

Abatacept, Ixazomib Citrate, and Dexamethasone in Treating Patients With Multiple Myeloma Resistant to Chemotherapy

Who this might be right for
Recurrent Plasma Cell MyelomaRefractory Plasma Cell Myeloma
Roswell Park Cancer Institute 15
Testing effectiveness (Phase 2)Study completedNCT00005854
What this trial is testing

Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+1 more
Fred Hutchinson Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT02938793
What this trial is testing

Durvalumab in Combination With Tremelimumab in Subjects With Advanced Rare Solid Tumors

Who this might be right for
CancerRare Disease
Prisma Health-Upstate 92
Early research (Phase 1)Active Not RecruitingNCT04606316
What this trial is testing

Surgical Nivolumab And Ipilimumab For Recurrent GBM

Who this might be right for
GlioblastomaGBMGlioblastoma Multiforme+1 more
Patrick Wen, MD 63
Early research (Phase 1)UnknownNCT05256719
What this trial is testing

Clinical Study of Recombinant Humanized CTLA-4-FC Fusion Protein Injection in Healthy Subjects

Who this might be right for
Health Volunteer
Beijing VDJBio Co., LTD. 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT05608044
What this trial is testing

Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Agenus Inc. 234
Early research (Phase 1)Study completedNCT00076934
What this trial is testing

Safety of RG2077 in Patients With Multiple Sclerosis

Who this might be right for
Multiple SclerosisMultiple Sclerosis, Relapsing-Remitting
National Institute of Allergy and Infectious Diseases (NIAID) 20
Early research (Phase 1)Ended earlyNCT02070406
What this trial is testing

Gene-Modified T Cells, Vaccine Therapy, and Ipilimumab in Treating Patients With Locally Advanced or Metastatic Malignancies

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Jonsson Comprehensive Cancer Center 4
Testing effectiveness (Phase 2)Active Not RecruitingNCT04140526
What this trial is testing

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

Who this might be right for
Non Small Cell Lung CancerAdvanced Solid TumorMetastatic Melanoma+16 more
OncoC4, Inc. 733
Early research (Phase 1)Study completedNCT02261220
What this trial is testing

MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
MedImmune LLC 380
Testing effectiveness (Phase 2)Study completedNCT01853618
What this trial is testing

Tremelimumab With Chemoembolization or Ablation for Liver Cancer

Who this might be right for
Heptocellular CancerBiliary Tract NeoplasmsLiver Cancer+2 more
National Cancer Institute (NCI) 61
Testing effectiveness (Phase 2)UnknownNCT06509971
What this trial is testing

QL1706 (an Anti-PD-1/CTLA-4 Combined Antibody) Combined With Albumin-bound Paclitaxel and Bevacizumab in the Treatment of Platinum-resistant Recurrent Ovarian Cancer

Who this might be right for
Platinum-resistant Recurrent Ovarian Cancer
West China Second University Hospital 39
Testing effectiveness (Phase 2)Study completedNCT03518606
What this trial is testing

Metronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours

Who this might be right for
Advanced Solid TumoursBreast CancerHead and Neck Cancer+2 more
UNICANCER 126
Testing effectiveness (Phase 2)Study completedNCT01804465
What this trial is testing

Sipuleucel-T With Immediate vs. Delayed Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Blockade for Prostate Cancer

Who this might be right for
Prostate Cancer
University of California, San Francisco 50
Testing effectiveness (Phase 2)Study completedNCT03852251
What this trial is testing

AK104, a PD-1/CTLA-4 Bispecific Antibody, for Advanced Solid Tumors or With mXELOX/XELOX as First-line Therapy for Advanced Gastric or GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaAdvanced Solid TumorsGastroesophageal Junction Adenocarcinoma
Akeso 338
Testing effectiveness (Phase 2)UnknownNCT06406673
What this trial is testing

A Phase II Clinical Study of Cadonilimab in Treatment-naïve or Relapsed Extensive Small Cell Lung Cancer

Who this might be right for
Extensive Small Cell Lung Cancer
Henan Cancer Hospital 70
Testing effectiveness (Phase 2)Study completedNCT02821754
What this trial is testing

A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)

Who this might be right for
Biliary Tract NeoplasmsLiver CancerHepatocellular Carcinoma+2 more
National Cancer Institute (NCI) 54
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