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Results for “CTLA-4”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT04338724
What this trial is testing

A Phase I Study of CS1002 in Subjects With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
CStone Pharmaceuticals 6
Early research (Phase 1)Active Not RecruitingNCT02879695
What this trial is testing

Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent Mixed Phenotype Acute LeukemiaRefractory B Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 28
Testing effectiveness (Phase 2)Ended earlyNCT03894215
What this trial is testing

RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer

Who this might be right for
Cervical Cancer
Agenus Inc. 211
Testing effectiveness (Phase 2)Looking for participantsNCT05187338
What this trial is testing

Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors

Who this might be right for
Lung CancerLiver CancerColorectal Cancer+8 more
Second Affiliated Hospital of Guangzhou Medical University 100
Not applicableStudy completedNCT04253080
What this trial is testing

Expression of IL4 Induced Gene 1 in Patients With Cutaneous Melanoma: Value in Prognosis and/or in Predictive Response to Immune Checkpoint Inhibitors

Who this might be right for
Cutaneous Melanoma
Assistance Publique - Hôpitaux de Paris 127
Testing effectiveness (Phase 2)WithdrawnNCT03982173
What this trial is testing

Basket Trial for Combination Therapy With Durvalumab (Anti-PDL1) (MEDI4736) and Tremelimumab (Anti-CTLA4) in Patients With Metastatic Solid Tumors

Who this might be right for
Metastatic Colorectal CancerTriple Negative Breast CancerProstate Adenocarcinoma+2 more
Gustave Roussy, Cancer Campus, Grand Paris
Testing effectiveness (Phase 2)Looking for participantsNCT06967103
What this trial is testing

QL1706 for the Neoadjuvant Treatment of HR+/HER2- Breast Cancer

Who this might be right for
Breast CancerHR+/HER2- Breast Cancer
Henan Cancer Hospital 238
Testing effectiveness (Phase 2)Looking for participantsNCT07232654
What this trial is testing

Iparomlimab/Tuvonralimab Injection Plus CCRT in LACC

Who this might be right for
LOCALLY ADVANCED CERVICAL CANCERS
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 30
Testing effectiveness (Phase 2)Ended earlyNCT06173505
What this trial is testing

Study of Vudalimab or Pembrolizumab in Combination With Chemotherapy as First-line Treatment in Patients With Advanced NSCLC

Who this might be right for
Nonsquamous Non-small Cell Lung Cancer
Xencor, Inc. 28
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07515469
What this trial is testing

A Prospective, Single-Arm, Exploratory Study of the Safety and Efficacy of Neoadjuvant Treatment With QL1706, an Anti-PD-1/Anti-CTLA-4 Bispecific Antibody, in Resectable Stage IB and IIA Hepatocellular Carcinoma With High Recurrence Risk

Who this might be right for
HCC - Hepatocellular CarcinomaIparomlimab and Tuvonralimab InjectionNeoadjuvant Immunotherapy
Tianjin Medical University Cancer Institute and Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06741644
What this trial is testing

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
CStone Pharmaceuticals 800
Testing effectiveness (Phase 2)Active Not RecruitingNCT06508606
What this trial is testing

AK117 (Anti-CD47 mAb) Plus Cetuximab or AK104 (Anti-PD-1/CTLA-4 bsAb) as Second-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
West China Hospital 20
Early research (Phase 1)Active Not RecruitingNCT05631899
What this trial is testing

CAR-DC Vaccine and ICIs in Local Advanced/Metastatic Solid Tumors

Who this might be right for
Solid Tumor, AdultEphA2 OverexpressionKRAS G12V+2 more
Chinese PLA General Hospital 9
Testing effectiveness (Phase 2)Study completedNCT04225390
What this trial is testing

Preconditioning of Tumor, Tumor Microenvironment and the Immune System to Immunotherapy

Who this might be right for
Immunotherapy
University of Erlangen-Nürnberg Medical School 38
Testing effectiveness (Phase 2)Active Not RecruitingNCT04556253
What this trial is testing

AK104 in Locally Advanced MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer

Who this might be right for
MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer
Peking University 47
Testing effectiveness (Phase 2)Study completedNCT03249142
What this trial is testing

Immunotherapy With Neo-adjuvant Chemotherapy for OVarian Cancer

Who this might be right for
Ovarian Cancer
ARCAGY/ GINECO GROUP 69
Testing effectiveness (Phase 2)Study completedNCT01896869
What this trial is testing

FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 83
Very early researchActive Not RecruitingNCT02812420
What this trial is testing

Durvalumab and Tremelimumab in Treating Patients With Muscle-Invasive, High-Risk Urothelial Cancer That Cannot Be Treated With Cisplatin-Based Therapy Before Surgery

Who this might be right for
HydronephrosisInfiltrating Bladder Urothelial Carcinoma Sarcomatoid VariantInfiltrating Bladder Urothelial Carcinoma, Micropapillary Variant+16 more
M.D. Anderson Cancer Center 54
Early research (Phase 1)Not Yet RecruitingNCT07619001
What this trial is testing

Evaluate the PK Similarity of AK104 in Healthy Chinese Male Participations

Who this might be right for
Healthy Male Adults Participants
Akeso 158
Testing effectiveness (Phase 2)WithdrawnNCT04007588
What this trial is testing

A Phase II Trial of Neoadjuvant Treatment With PD-1 Inhibition (Nivolumab) With or Without IDO Inhibition (BMS-986205) and With or Without CTLA-4 Inhibition (Ipilimumab) in Resectable Stage III or IV Melanoma

Who this might be right for
Melanoma Stage IIIMelanoma Stage IV
Dana-Farber Cancer Institute
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