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Results for “CYP3A Inhibitor”

41 trials

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Showing 20 of 41 results

Early research (Phase 1)Study completedNCT03624959
What this trial is testing

Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A

Who this might be right for
Healthy Volunteer
Celgene 100
Early research (Phase 1)Study completedNCT03512548
What this trial is testing

Study in Healthy Subjects to Determine the Effect of an Inhibitor on Exposure to Relacorilant and Its Metabolites

Who this might be right for
Healthy
Corcept Therapeutics 52
Early research (Phase 1)Study completedNCT03028103
What this trial is testing

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Who this might be right for
Diffuse Large B Cell LymphomaPrimary Mediastinal LymphomaMantle Cell Lymphoma+2 more
Epizyme, Inc. 32
Early research (Phase 1)Looking for participantsNCT07402915
What this trial is testing

Drug-drug Interaction Study With AZD5335 and Itraconazole in Participants With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Who this might be right for
Fallopian Tube CancerOvarian CancerPrimary Peritoneal
AstraZeneca 24
Early research (Phase 1)Study completedNCT01323257
What this trial is testing

TMC435-TiDP16-C115 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Erythromycin and Between TMC435 and Darunavir/Ritonavir (DRV/r)

Who this might be right for
Hepatitis C Virus
Tibotec Pharmaceuticals, Ireland 49
Early research (Phase 1)Study completedNCT02058277
What this trial is testing

A Drug Interaction Study Between Bosutinib And Aprepitant In Healthy Volunteers

Who this might be right for
Healthy
Pfizer 20
Early research (Phase 1)Study completedNCT05720767
What this trial is testing

HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study

Who this might be right for
Relapsed or Refractory Lymphoma
Hutchmed 28
Early research (Phase 1)Study completedNCT03222310
What this trial is testing

Evaluate the Effect of a Potent Cytochrome P450 (CYP) 3A Inhibitor on Ipatasertib

Who this might be right for
Healthy Volunteers
Hoffmann-La Roche 15
Early research (Phase 1)Study completedNCT04372407
What this trial is testing

Assess the Effect of a Strong CYP3A Inhibitor, on Surufatinib in Healthy Subjects

Who this might be right for
Healthy
Hutchison Medipharma Limited 13
Early research (Phase 1)Ended earlyNCT05494866
What this trial is testing

A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients with Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
CYP3A InhibitorAdvanced Stage or Metastatic Pancreatic Ductal AdenocarcinomaPancreatic Cancer+2 more
German Cancer Research Center 6
Early research (Phase 1)Study completedNCT03259542
What this trial is testing

Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor

Who this might be right for
Drug Interaction PotentiationHealthy
Corcept Therapeutics 33
Early research (Phase 1)Study completedNCT06495944
What this trial is testing

Impact of Itraconazole on the Pharmacokinetics and Safety of Dazucorilant in Healthy, Adult Participants

Who this might be right for
Healthy Adults
Corcept Therapeutics 21
Early research (Phase 1)Study completedNCT05492318
What this trial is testing

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

Who this might be right for
Drug-Drug InteractionHeathy Volunteer
Italfarmaco 26
Early research (Phase 1)Study completedNCT05602597
What this trial is testing

HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPI

Who this might be right for
Relapsed or Refractory Lymphoma
Hutchmed 59
Early research (Phase 1)Study completedNCT03333824
What this trial is testing

Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer

Who this might be right for
Solid Tumours
AstraZeneca 33
Early research (Phase 1)Study completedNCT07697157
What this trial is testing

The Study on Effects of CYP3A and P-glycoprotein Inhibitor Itraconazole and CYP Enzyme Inducer Rifampin of HMPL-453 Tartrate Tablets

Who this might be right for
Health, Subjective
Hutchmed 40
Early research (Phase 1)Study completedNCT03301181
What this trial is testing

Phase 1 Study to Investigate Effect of Rifampin and Itraconazole on the Pharmacokinetics of BGB-3111 in Healthy Subjects

Who this might be right for
Healthy Volunteers: Asian, Non-Asian
BeiGene 40
Early research (Phase 1)Study completedNCT05372367
What this trial is testing

A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor

Who this might be right for
Solid Tumors
Boehringer Ingelheim 33
Early research (Phase 1)Study completedNCT02175407
What this trial is testing

Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects

Who this might be right for
PharmacokineticsDDI (Drug-Drug Interaction)Healthy Subjects
Astellas Pharma Europe B.V. 14
Testing effectiveness (Phase 2)Active Not RecruitingNCT07341100
What this trial is testing

Study to Evaluate the Preliminary Efficacy of SKB264 and the Effect of Clarithromycin on the PK of SKB264 in OC

Who this might be right for
Ovarian Epithelial Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 20
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