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Results for “CYP3A Inhibitor”

38 trials

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Showing 20 of 38 results

Early research (Phase 1)Study completedNCT03535662
What this trial is testing

A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers

Who this might be right for
Pharmacokinetic Study in Healthy Male Volunteers
Nerre Therapeutics Ltd. 16
Early research (Phase 1)Ended earlyNCT05494866
What this trial is testing

A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients with Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
CYP3A InhibitorAdvanced Stage or Metastatic Pancreatic Ductal AdenocarcinomaPancreatic Cancer+2 more
German Cancer Research Center 6
Early research (Phase 1)Study completedNCT02809768
What this trial is testing

Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole, Itraconazole, or Rifampin in Healthy Subjects

Who this might be right for
Healthy Participants
Eisai Inc. 48
Early research (Phase 1)Study completedNCT03383692
What this trial is testing

Study of DS-8201a for Participants With Advanced Solid Malignant Tumors

Who this might be right for
Neoplasm Metastasis
Daiichi Sankyo Co., Ltd. 40
Early research (Phase 1)Study completedNCT04958226
What this trial is testing

Assess the Effect of Capivasertib on Midazolam in Patients With Advanced Solid Tumours

Who this might be right for
Solid Tumour
AstraZeneca 21
Early research (Phase 1)Study completedNCT05492318
What this trial is testing

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

Who this might be right for
Drug-Drug InteractionHeathy Volunteer
Italfarmaco 26
Early research (Phase 1)Study completedNCT02175407
What this trial is testing

Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects

Who this might be right for
PharmacokineticsDDI (Drug-Drug Interaction)Healthy Subjects
Astellas Pharma Europe B.V. 14
Early research (Phase 1)Study completedNCT05720767
What this trial is testing

HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study

Who this might be right for
Relapsed or Refractory Lymphoma
Hutchmed 28
Early research (Phase 1)Study completedNCT05372367
What this trial is testing

A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor

Who this might be right for
Solid Tumors
Boehringer Ingelheim 33
Early research (Phase 1)Study completedNCT01984229
What this trial is testing

The Effects of Posaconazole on Alectinib (RO5424802) Pharmacokinetics in Healthy Volunteers

Who this might be right for
Healthy Volunteer
Hoffmann-La Roche 23
Early research (Phase 1)Study completedNCT05826574
What this trial is testing

Assess Pharmacokinetics (PK) of Brensocatib Alone and With Multiple Doses of Rifampin or Esomeprozole in Healthy Participants

Who this might be right for
Healthy Volunteers
Insmed Incorporated 32
Early research (Phase 1)Study completedNCT03499106
What this trial is testing

A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers

Who this might be right for
Healthy
Cyclerion Therapeutics 24
Early research (Phase 1)Study completedNCT02381080
What this trial is testing

Interaction Study of Ibrutinib and Cytochrome P450 (CYP) 3A Inhibitors in Participants With B-cell Malignancy

Who this might be right for
B-Cell Chronic Lymphocytic Leukemia
Janssen Research & Development, LLC 26
Early research (Phase 1)Study completedNCT05602597
What this trial is testing

HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPI

Who this might be right for
Relapsed or Refractory Lymphoma
Hutchmed 59
Early research (Phase 1)Study completedNCT02259010
What this trial is testing

Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma

Who this might be right for
Advanced Solid TumorsRelapsed/Refractory Lymphoma
Millennium Pharmaceuticals, Inc. 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07341100
What this trial is testing

Study to Evaluate the Preliminary Efficacy of SKB264 and the Effect of Clarithromycin on the PK of SKB264 in OC

Who this might be right for
Ovarian Epithelial Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 20
Early research (Phase 1)Study completedNCT03259542
What this trial is testing

Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor

Who this might be right for
Drug Interaction PotentiationHealthy
Corcept Therapeutics 33
Early research (Phase 1)Study completedNCT01323257
What this trial is testing

TMC435-TiDP16-C115 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Erythromycin and Between TMC435 and Darunavir/Ritonavir (DRV/r)

Who this might be right for
Hepatitis C Virus
Tibotec Pharmaceuticals, Ireland 49
Early research (Phase 1)Study completedNCT03624959
What this trial is testing

Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A

Who this might be right for
Healthy Volunteer
Celgene 100
Early research (Phase 1)Study completedNCT03451110
What this trial is testing

Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects

Who this might be right for
Healthy Subjects
Eisai Inc. 50
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