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Results for “CYP3A Inhibitor”

39 trials

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Showing 20 of 39 results

Early research (Phase 1)Study completedNCT01984229
What this trial is testing

The Effects of Posaconazole on Alectinib (RO5424802) Pharmacokinetics in Healthy Volunteers

Who this might be right for
Healthy Volunteer
Hoffmann-La Roche 23
Early research (Phase 1)Study completedNCT03301181
What this trial is testing

Phase 1 Study to Investigate Effect of Rifampin and Itraconazole on the Pharmacokinetics of BGB-3111 in Healthy Subjects

Who this might be right for
Healthy Volunteers: Asian, Non-Asian
BeiGene 40
Early research (Phase 1)Study completedNCT04557397
What this trial is testing

Fruquintinib CYP3A Inhibitor and Inducer Study

Who this might be right for
Drug Drug Interaction
Hutchison Medipharma Limited 28
Early research (Phase 1)Study completedNCT01323257
What this trial is testing

TMC435-TiDP16-C115 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Erythromycin and Between TMC435 and Darunavir/Ritonavir (DRV/r)

Who this might be right for
Hepatitis C Virus
Tibotec Pharmaceuticals, Ireland 49
Early research (Phase 1)Study completedNCT03499106
What this trial is testing

A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers

Who this might be right for
Healthy
Cyclerion Therapeutics 24
Early research (Phase 1)Study completedNCT05602597
What this trial is testing

HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPI

Who this might be right for
Relapsed or Refractory Lymphoma
Hutchmed 59
Early research (Phase 1)Study completedNCT02381080
What this trial is testing

Interaction Study of Ibrutinib and Cytochrome P450 (CYP) 3A Inhibitors in Participants With B-cell Malignancy

Who this might be right for
B-Cell Chronic Lymphocytic Leukemia
Janssen Research & Development, LLC 26
Early research (Phase 1)Study completedNCT04551963
What this trial is testing

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

Who this might be right for
B-cell Malignancies
BeiGene 26
Early research (Phase 1)Study completedNCT03535662
What this trial is testing

A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers

Who this might be right for
Pharmacokinetic Study in Healthy Male Volunteers
Nerre Therapeutics Ltd. 16
Early research (Phase 1)Study completedNCT04510649
What this trial is testing

Surufatinib DDI With a PPI and a CYP3A Inducer

Who this might be right for
Healthy
Hutchison Medipharma Limited 28
Early research (Phase 1)Ended earlyNCT05494866
What this trial is testing

A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients with Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
CYP3A InhibitorAdvanced Stage or Metastatic Pancreatic Ductal AdenocarcinomaPancreatic Cancer+2 more
German Cancer Research Center 6
Early research (Phase 1)Study completedNCT02175407
What this trial is testing

Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects

Who this might be right for
PharmacokineticsDDI (Drug-Drug Interaction)Healthy Subjects
Astellas Pharma Europe B.V. 14
Early research (Phase 1)Study completedNCT02809768
What this trial is testing

Study to Assess Pharmacokinetic Drug-Drug Interaction Between Avatrombopag When Co-Administered With Fluconazole, Itraconazole, or Rifampin in Healthy Subjects

Who this might be right for
Healthy Participants
Eisai Inc. 48
Early research (Phase 1)Looking for participantsNCT07402915
What this trial is testing

Drug-drug Interaction Study With AZD5335 and Itraconazole in Participants With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Who this might be right for
Fallopian Tube CancerOvarian CancerPrimary Peritoneal
AstraZeneca 24
Early research (Phase 1)Study completedNCT03961997
What this trial is testing

Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants

Who this might be right for
AdultDrug InteractionsHealthy Volunteers+1 more
Pfizer 16
Early research (Phase 1)Study completedNCT03333824
What this trial is testing

Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer

Who this might be right for
Solid Tumours
AstraZeneca 33
Early research (Phase 1)Study completedNCT06543043
What this trial is testing

Evaluate the Effects of Phenytoin and Itraconazole on Sonrotoclax (BGB-11417) in Healthy Volunteers

Who this might be right for
Not Determined
BeiGene 30
Early research (Phase 1)Study completedNCT05720767
What this trial is testing

HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study

Who this might be right for
Relapsed or Refractory Lymphoma
Hutchmed 28
Early research (Phase 1)Study completedNCT03259542
What this trial is testing

Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor

Who this might be right for
Drug Interaction PotentiationHealthy
Corcept Therapeutics 33
Early research (Phase 1)Study completedNCT02259010
What this trial is testing

Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma

Who this might be right for
Advanced Solid TumorsRelapsed/Refractory Lymphoma
Millennium Pharmaceuticals, Inc. 24
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