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Results for “Cancer (With CNS Involvement)”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07812493
What this trial is testing

Pirtobrutinib Plus Methotrexate-Based Chemoimmunotherapy for Systemic DLBCL With CNS Involvement

Who this might be right for
PirtobrutinibImmunochemotherapyDLBCL - Diffuse Large B Cell Lymphoma+1 more
Pengpeng Xu 24
Testing effectiveness (Phase 2)Ended earlyNCT05022797
What this trial is testing

Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNS

Who this might be right for
Diffuse Large B-Cell LymphomaDrug Toxicity
Fundacion CRIS de Investigación para Vencer el Cáncer 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT05256290
What this trial is testing

Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations

Who this might be right for
Non-Small Cell Lung CancerAdvanced Non-Small Cell Squamous Lung CancerMetastatic Lung Non-Small Cell Carcinoma+7 more
Black Diamond Therapeutics, Inc. 200
Not applicableUnknownNCT05305885
What this trial is testing

Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 100
Testing effectiveness (Phase 2)Looking for participantsNCT07206498
What this trial is testing

Evaluate Safety and Efficacy of WSD0922-FU Combo With Osimertinib for NSCLC

Who this might be right for
Non Small Cell Lung Cancer (NSCLC)
Wayshine Biopharm, Inc. 48
Testing effectiveness (Phase 2)Study completedNCT00541138
What this trial is testing

Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord Tumors

Who this might be right for
Brain and Central Nervous System TumorsMetastatic CancerUnspecified Adult Solid Tumor, Protocol Specific
City of Hope Medical Center 50
Early research (Phase 1)Ended earlyNCT03711422
What this trial is testing

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal DiseaseCentral Nervous System Metastases
National Cancer Centre, Singapore 2
Not applicableStudy completedNCT02341950
What this trial is testing

Clinical Trial of a Serious Game for Individuals With SCI/D

Who this might be right for
Spinal Cord InjurySpinal Cord InvolvementSpina Bifida+6 more
University of Michigan 184
Not applicableWithdrawnNCT01312506
What this trial is testing

Collection of Cerebrospinal Fluid and Tumor Tissue in Subjects With Metastatic Melanoma and Controls

Who this might be right for
Metastatic MelanomaCNS Metastases
University of Pittsburgh
Large-scale testing (Phase 3)Looking for participantsNCT06500481
What this trial is testing

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
NRG Oncology 115
Testing effectiveness (Phase 2)Study completedNCT00801216
What this trial is testing

High-dose Sequential Chemoimmunotherapy for B-cell Lymphomas With Central Nervous System Involvement

Who this might be right for
B-cell Lymphomas
Andrés José Maria Ferreri 40
Early research (Phase 1)Study completedNCT01048008
What this trial is testing

Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer

Who this might be right for
Advanced CancerBrain Involvement
DEKK-TEC, Inc. 22
Early research (Phase 1)WithdrawnNCT06137651
What this trial is testing

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Who this might be right for
Breast CarcinomaMetastatic Malignant Neoplasm in the BrainMetastatic Malignant Neoplasm in the Leptomeninges
Northwestern University
Early research (Phase 1)Ended earlyNCT00031577
What this trial is testing

Paclitaxel Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Children's Hospital of Philadelphia 11
Testing effectiveness (Phase 2)Study completedNCT00450866
What this trial is testing

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer

Who this might be right for
Breast CancerMetastatic Cancer
David Peereboom, MD 55
Testing effectiveness (Phase 2)Study completedNCT00553943
What this trial is testing

Phase II Study to Evaluate the Combination of Rituximab and DepoCyte® in the C5R Chemotherapy Protocol in Patients Between the Ages of 18 and 60 Years With Primary Cerebral Non-Hodgkin Lymphoma and Systemic Diffuse Large B-cell Lymphoma With Neuromeningeal Invasion at Diagnosis

Who this might be right for
Lymphoma, Non-HodgkinDiffuse Large B-cell Lymphoma
Lymphoma Study Association 60
Testing effectiveness (Phase 2)Ended earlyNCT00570908
What this trial is testing

Brain Mets - Capecitabine Plus Sunitinib and WBRT

Who this might be right for
Breast Cancer
Baylor Breast Care Center 12
Not applicableLooking for participantsNCT06026735
What this trial is testing

Non-small Cell Lung Cancer With Central Nervous System Metastasis

Who this might be right for
Lung Cancer With Central Nervous System Metastasis
National Taiwan University Hospital 30
Large-scale testing (Phase 3)Looking for participantsNCT07413939
What this trial is testing

RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive

Who this might be right for
HER2-positive Breast Cancer
Hoffmann-La Roche 650
Testing effectiveness (Phase 2)UnknownNCT02927340
What this trial is testing

Lorlatinib in Advanced ALK and ROS1 Rearranged Lung Cancer With CNS Metastasis in the Absence of Measurable Extracranial Lesions

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)
Massachusetts General Hospital 30
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