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Results for “Cancer Gene Mutation”

2,750 trials

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Showing 20 of 2,750 results

Testing effectiveness (Phase 2)WithdrawnNCT05279859
What this trial is testing

Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia
Erasca, Inc.
Not applicableLooking for participantsNCT04151342
What this trial is testing

CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

Who this might be right for
CancerMalignancies MultipleMalignant Solid Tumor+7 more
University Health Network, Toronto 5,500
Not applicableUnknownNCT05604573
What this trial is testing

DNA Mutation Detection in Circulating Tumor DNA and Tissue by mmADPS for Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Seoul National University Hospital 150
Not applicableUnknownNCT04909073
What this trial is testing

Observational Study of Afatinib 30 mg Daily

Who this might be right for
Non-Small Cell Lung CancerEpidermal Growth Factor Receptor Mutation
National University Hospital, Singapore 69
Testing effectiveness (Phase 2)WithdrawnNCT02355431
What this trial is testing

Itacitinib in Combination With Erlotinib in Non Small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor (EGFR) Activating Mutations

Who this might be right for
Solid Tumors and Hematologic MalignancyNSCLC (Non-small Cell Lung Carcinoma)
Incyte Corporation
Not applicableNot Yet RecruitingNCT07244588
What this trial is testing

Shaving as an Safe Alternative to Frozen Section Analysis

Who this might be right for
Early Stage Breast Cancer
Mark Ezzat Gerges 30
Large-scale testing (Phase 3)UnknownNCT02387086
What this trial is testing

Gefitinib Combined With Thalidomide to Treat NSCLC

Who this might be right for
NSCLC
Bai Jun 380
Early research (Phase 1)Looking for participantsNCT06484556
What this trial is testing

T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

Who this might be right for
Tumor, Solid
Tao Zhang 9
Not applicableUnknownNCT03837054
What this trial is testing

Does Chemotherapy Train the Mutation of the Pig-A Gene? (PIGA)

Who this might be right for
Breast Cancer Female
Assistance Publique Hopitaux De Marseille 30
Testing effectiveness (Phase 2)UnknownNCT02407366
What this trial is testing

Icotinib With Concurrent Radiotherapy vs. Chemoradiotherapy in Non-small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
People's Hospital of Guangxi Zhuang Autonomous Region 80
Not applicableLooking for participantsNCT05378204
What this trial is testing

Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer.

Who this might be right for
Breast Cancer
Institut Claudius Regaud 120
Not applicableStudy completedNCT04560270
What this trial is testing

CIrculating Tumor DNA for Monitoring Response to First Line Chemotherapy in Unresectable PANcreatic Cancer

Who this might be right for
Pancreatic CancerCirculating Tumor DNAKRAS Mutation-Related Tumors
Poitiers University Hospital 69
Testing effectiveness (Phase 2)UnknownNCT01131429
What this trial is testing

A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR Mutations

Who this might be right for
Neoplasms, LungCarcinoma, Non-Small Cell LungDrug Therapy+1 more
Chinese PLA General Hospital 60
Early research (Phase 1)Study completedNCT01636622
What this trial is testing

Study of Vemurafenib, Carboplatin, and Paclitaxel

Who this might be right for
Advanced Cancers
M.D. Anderson Cancer Center 21
Testing effectiveness (Phase 2)Active Not RecruitingNCT03093922
What this trial is testing

Two Dosing Schedules of Atezolizumab in Combination With Gemcitabine and Cisplatin as First-Line Treatment for Metastatic Bladder Cancer

Who this might be right for
Urothelial CarcinomaLocally AdvancedUnresectable
Memorial Sloan Kettering Cancer Center 32
Early research (Phase 1)Active Not RecruitingNCT07038369
What this trial is testing

ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations

Who this might be right for
Advanced Solid TumorsBreast CancerBreast Carcinoma+24 more
Atavistik Bio, Inc 134
Testing effectiveness (Phase 2)Looking for participantsNCT05536505
What this trial is testing

Adjuvant Treatment Based on MRD for EGFR Mutant NSCLC

Who this might be right for
MRD
Guangdong Association of Clinical Trials 180
Testing effectiveness (Phase 2)Ended earlyNCT04030429
What this trial is testing

Crizotinib in c-MET Mutation Metastatic/Recurrent/Persistent Endometrial Cancer

Who this might be right for
Endometrial Cancer Recurrent
National Cheng-Kung University Hospital 40
Not applicableStudy completedNCT03471572
What this trial is testing

Study to Assess Prevalence of BRCA1 and BRCA2 Mutation Among Ovarian, Primary Peritoneal and Fallopian Tube Cancer Patients in India

Who this might be right for
Ovarian Cancer
AstraZeneca 240
Not applicableUnknownNCT02156297
What this trial is testing

Sorafenib to Treat FLT3-ITD AML

Who this might be right for
Acute Myeloid LeukemiaFLT3-ITD Mutation
The First Affiliated Hospital of Soochow University 100
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