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Results for “Cancer Gene Mutation”

2,695 trials

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Showing 20 of 2,695 results

Testing effectiveness (Phase 2)UnknownNCT05005468
What this trial is testing

A Phase II Trial of Camrelizumab Combined With Famitinib for Adjuvant Treatment of Stage II-IIIA NSCLC.

Who this might be right for
NSCLC
Shanghai Chest Hospital 61
Testing effectiveness (Phase 2)Looking for participantsNCT06728410
What this trial is testing

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

Who this might be right for
Intrahepatic CholangiocarcinomaFGFR2 Gene RearrangementFGFR2 Gene Mutation
Mehmet Akce 38
Testing effectiveness (Phase 2)Study completedNCT04042558
What this trial is testing

A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer With EGFR Mutations, ALK Rearrangement or ROS1 Fusion Progressing After Targeted Therapies

Who this might be right for
NSCLC Stage IIIBNSCLC Stage IVEGFR Gene Mutation+2 more
Centre Francois Baclesse 150
Large-scale testing (Phase 3)UnknownNCT02001896
What this trial is testing

Erlotinib Intercalated With Chemotherapy Versus Erlotinib as First Line Treatment in Stage IIIB/IV NSCLC Patients With EGFR Mutation

Who this might be right for
Non-Small Cell Lung Cancer
Xinjiang Medical University 60
Not applicableUnknownNCT05411276
What this trial is testing

A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2

Who this might be right for
HER2 Mutant Non-small Cell Lung Cancer
Beijing Chest Hospital 15
Testing effectiveness (Phase 2)Ended earlyNCT04310397
What this trial is testing

Dabrafenib, Trametinib, and Spartalizumab for the Treatment of BRAF V600E or V600K Mutation Positive Stage IIIB/C/D Melanoma

Who this might be right for
Pathologic Stage IIIB Cutaneous Melanoma AJCC v8Pathologic Stage IIIC Cutaneous Melanoma AJCC v8Pathologic Stage IIID Cutaneous Melanoma AJCC v8
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)WithdrawnNCT02965417
What this trial is testing

Sym004 in Metastatic Colorectal Cancer and ECD-EGFR Patients

Who this might be right for
Metastatic Colorectal Cancer
Symphogen A/S
Testing effectiveness (Phase 2)Ended earlyNCT01555489
What this trial is testing

Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca

Who this might be right for
Stage IV Pancreatic Cancer
Thomas Jefferson University 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT05379946
What this trial is testing

Study to Evaluate D-1553 in Combination With IN10018 in Subjects With Solid Tumors

Who this might be right for
Solid Tumor
InventisBio Co., Ltd 92
Testing effectiveness (Phase 2)UnknownNCT03646968
What this trial is testing

Study of Anlotinib Combined With Docetaxel in Non-Driver Mutation Non-squamous NSCLC: the Save Study

Who this might be right for
Non-Squamous Non Small Cell Lung Cancer
Yongchang Zhang 43
Post-approval studies (Phase 4)Ended earlyNCT01683188
What this trial is testing

HD IL-2 + Vemurafenib in Patients With BRAF Mutation Positive Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Clinigen, Inc. 53
Testing effectiveness (Phase 2)UnknownNCT02681562
What this trial is testing

Olaparib in Locally Advanced ER, PgR and HER2 Negative (Triple Negative) and in Locally Advanced Germline BRCA Mutation-positive Breast Cancer Patients

Who this might be right for
Breast CancerTriple Negative Breast Cancer
Istituti Ospitalieri di Cremona 45
Testing effectiveness (Phase 2)Ended earlyNCT04488003
What this trial is testing

Study of Ulixertinib for Patients With Advanced Malignancies Harboring MEK or Atypical BRAF Alterations

Who this might be right for
Advanced Solid TumorBRAF Gene MutationBRAF Gene Alteration+6 more
BioMed Valley Discoveries, Inc 104
Early research (Phase 1)Looking for participantsNCT06659341
What this trial is testing

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

Who this might be right for
Advanced Solid Tumors Harboring KRAS G12C Mutation
Bayer 104
Early research (Phase 1)Looking for participantsNCT07524322
What this trial is testing

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

Who this might be right for
Breast CancerOvarian CancerEndometrial Cancer+6 more
Regor Pharmaceuticals Inc. 63
Testing effectiveness (Phase 2)Active Not RecruitingNCT04699188
What this trial is testing

Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

Who this might be right for
KRAS G12C Mutant Solid TumorsCarcinoma, Non-Small-Cell LungCarcinoma, Colorectal+7 more
Novartis Pharmaceuticals 344
Testing effectiveness (Phase 2)Study completedNCT01802320
What this trial is testing

Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

Who this might be right for
Colon Mucinous AdenocarcinomaColon Signet Ring Cell AdenocarcinomaRectal Mucinous Adenocarcinoma+13 more
National Cancer Institute (NCI) 18
Testing effectiveness (Phase 2)Study completedNCT03007979
What this trial is testing

Alternative Dosing Schedule of Palbociclib in Metastatic Hormone Receptor Positive Breast Cancer

Who this might be right for
Breast CancerBreast CarcinomaCancer of Breast+1 more
Washington University School of Medicine 55
Not applicableStudy completedNCT00897754
What this trial is testing

Gene Expression in Patients With Advanced or Metastatic Colorectal Cancer Receiving Bevacizumab

Who this might be right for
Colorectal Cancer
ECOG-ACRIN Cancer Research Group 200
Testing effectiveness (Phase 2)Study completedNCT00094445
What this trial is testing

Trial of Curcumin in Advanced Pancreatic Cancer

Who this might be right for
Pancreatic NeoplasmsAdenocarcinoma
M.D. Anderson Cancer Center 50
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