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Results for “Cancers With DNA Repair-Deficiency”

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Showing 20 of 0 results

Not applicableUnknownNCT06447961
What this trial is testing

PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome

Who this might be right for
Lynch SyndromePolyposis Syndrome, Hereditary Mixed, 1Polyposis Syndrome, Hereditary Mixed, 2
London North West Healthcare NHS Trust 66
Large-scale testing (Phase 3)Active Not RecruitingNCT02912559
What this trial is testing

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Who this might be right for
Colon AdenocarcinomaDNA Repair DisorderLynch Syndrome+1 more
National Cancer Institute (NCI) 712
Very early researchWithdrawnNCT06246786
What this trial is testing

Breast/Cyclosporin A/TNBC (Triple Negative Breast Cancer)

Who this might be right for
Triple Negative Breast CancerDNA Damage Repair Deficiency
Virginia G. Kaklamani
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Not applicableStudy completedNCT00187057
What this trial is testing

Study for Treatment of Cancer in Children With Ataxia-telangiectasia

Who this might be right for
Ataxia-Telangiectasia
St. Jude Children's Research Hospital 6
Not applicableStudy completedNCT02645084
What this trial is testing

Identifying Patients With Hereditary and Familial Colorectal Cancer by Using an Online Risk Tool

Who this might be right for
Colorectal CancerLynch SyndromeFamilial Colorectal Cancer
Prof. Evelien Dekker, MD, PhD 104
Testing effectiveness (Phase 2)Study completedNCT03127215
What this trial is testing

Study of Olaparib/Trabectedin vs. Doctor's Choice in Solid Tumors

Who this might be right for
Cancers With DNA Repair-Deficiency
National Center for Tumor Diseases, Heidelberg 102
Not applicableStudy completedNCT04966923
What this trial is testing

Phenotype and Prognosis of Patients With Breast Cancer and Pathogenic Variants of TP53

Who this might be right for
Breast CancerTP53 R337HLi-Fraumeni Syndrome+1 more
Instituto do Cancer do Estado de São Paulo 135
Not applicableStudy completedNCT02198092
What this trial is testing

Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes

Who this might be right for
Familial Adenomatous PolyposisMap SyndromeLynch Syndrome+2 more
University of Pennsylvania 24
Testing effectiveness (Phase 2)Looking for participantsNCT07262619
What this trial is testing

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

Who this might be right for
Advanced Solid TumorsMSI-H or dMMR Advanced Solid TumorsMSI-H/dMMR Gastric Cancer+4 more
Eikon Therapeutics 160
Not applicableStudy completedNCT00450424
What this trial is testing

Educational CD-ROM Compared With Standard Informed Consent for Patients With Colorectal Cancer or a Family History of Colorectal Cancer

Who this might be right for
Colorectal CancerHereditary Non-polyposis Colon Cancer
Fox Chase Cancer Center 239
Not applicableUnknownNCT05728814
What this trial is testing

DOstarlimab in Patients With Recurrent or dMMR/MSI-H Endometrial Cancer

Who this might be right for
Endometrial Cancer
Grupo Español de Investigación en Cáncer de Ovario 100
Early research (Phase 1)Study completedNCT01981525
What this trial is testing

A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome

Who this might be right for
Li-Fraumeni Syndrome
National Cancer Institute (NCI) 26
Testing effectiveness (Phase 2)Ended earlyNCT03875313
What this trial is testing

Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors

Who this might be right for
Solid TumorClear Cell Renal Cell CarcinomaTNBC - Triple-Negative Breast Cancer+4 more
Calithera Biosciences, Inc 33
Not applicableUnknownNCT05909410
What this trial is testing

Perception About Benefits and Risks Related to Combined Hormonal Contraceptives Use in Patients With Lynch Syndrome

Who this might be right for
Lynch SyndromeContraception
Piazza della Vittoria 14 Studio Medico - Ginecologia e Ostetricia 180
Not applicableStudy completedNCT00005892
What this trial is testing

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia

Who this might be right for
Fanconi's AnemiaMyelodysplastic SyndromesLeukemia, Nonlymphocytic, Acute+1 more
Fairview University Medical Center
Large-scale testing (Phase 3)Study completedNCT02975934
What this trial is testing

Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

Who this might be right for
Metastatic Castration Resistant Prostate Cancer
pharmaand GmbH 405
Testing effectiveness (Phase 2)Ended earlyNCT04155190
What this trial is testing

Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

Who this might be right for
Recurrent Basal Cell Carcinoma
Sol-Gel Technologies, Ltd. 50
Not applicableStudy completedNCT04131062
What this trial is testing

Trial to Compare eConsent With Standard Consent Among Prospective Biobank Participants

Who this might be right for
Lynch Syndrome
Geisinger Clinic 703
Testing effectiveness (Phase 2)Looking for participantsNCT07371663
What this trial is testing

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

Who this might be right for
Solid CancersNSCLC (Advanced Non-small Cell Lung Cancer)Gastric (Stomach) Cancer+2 more
Beijing Tide Pharmaceutical Co., Ltd 266
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