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Results for “Carcinomatous Meningitis”

165 trials

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Showing 20 of 165 results

Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Not applicableNot Yet RecruitingNCT07348965
What this trial is testing

Pulsatile High-dose Furmonertinib in EGFR-mutant NSCLC With Leptomeningeal Metastasis

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)Leptomeningeal MetastasisFurmonertinib+1 more
Guangzhou University of Traditional Chinese Medicine 42
Testing effectiveness (Phase 2)Looking for participantsNCT06376292
What this trial is testing

A Prospective Single Arm Phase II Exploratory Study on the Combination of Whole Brain Radiotherapy, Thiotepa Intrathecal Injection and Systemic Treatment of Primary Diseases in the Treatment of Solid Tumor Leptomeningeal Metastasis

Who this might be right for
Solid Tumor Leptomeningeal Metastasis
Second Affiliated Hospital, School of Medicine, Zhejiang University 58
Early research (Phase 1)Ended earlyNCT00089245
What this trial is testing

Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer

Who this might be right for
Brain and Central Nervous System TumorsNeuroblastomaSarcoma
Y-mAbs Therapeutics 177
Not applicableLooking for participantsNCT05746325
What this trial is testing

Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Leptomeninges+2 more
Mayo Clinic 5
Testing effectiveness (Phase 2)Study completedNCT00005811
What this trial is testing

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

Who this might be right for
AIDS-related Diffuse Large Cell LymphomaAIDS-related Diffuse Mixed Cell LymphomaAIDS-related Diffuse Small Cleaved Cell Lymphoma+17 more
National Cancer Institute (NCI) 77
Testing effectiveness (Phase 2)Looking for participantsNCT06901817
What this trial is testing

The Safety and Efficacy of Pemetrexed Combined with Nivolumab Via Intraventricular Injection for the Treatment of Refractory Non-squamous Non-small Cell Lung Cancer with Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastasis
Shanghai Cancer Hospital, China 97
Testing effectiveness (Phase 2)Looking for participantsNCT06809530
What this trial is testing

Intrathecal Dual Checkpoint Inhibitor (PD-1 and CTLA-4) in Combination With Pemetrexed for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisPemetrexedPD-1 Inhibitor+2 more
Guangzhou Medical University 34
Not applicableUnknownNCT00938756
What this trial is testing

Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meningeal Syndrome

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerMetastatic Cancer
Centre Oscar Lambret 80
Early research (Phase 1)Looking for participantsNCT05184816
What this trial is testing

Deferoxamine (DFO) in People With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 35
Not applicableLooking for participantsNCT06399926
What this trial is testing

Efficacy and Safety of Intraventricule Pemetrexed Disodium Administered Via Ommaya Reservoir

Who this might be right for
Leptomeningeal MetastasisLung Cancer
Xiangya Hospital of Central South University 64
Testing effectiveness (Phase 2)Study completedNCT04563871
What this trial is testing

Efficacy and Safety of 80mg Osimertinib in Patients With Non-small Cell Lung Cancer(NSCLC)

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Samsung Medical Center 73
Early research (Phase 1)Active Not RecruitingNCT05598853
What this trial is testing

Intrathecal Double Checkpoint Inhibition

Who this might be right for
Leptomeningeal MetastasisNon-small Cell Lung Cancer Stage IVMelanoma Stage IV
University of Zurich 26
Not applicableLooking for participantsNCT05257967
What this trial is testing

CSF Analysis in EGFR Mutant Non-Small Cell Lung Cancer with Leptomeningeal Disease

Who this might be right for
EGFR Activating MutationLeptomeningeal MetastasisNon Small Cell Lung Cancer
British Columbia Cancer Agency 10
Post-approval studies (Phase 4)UnknownNCT04356222
What this trial is testing

Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisDurvalumab
Hui Bu 30
Early research (Phase 1)Study completedNCT00416923
What this trial is testing

Intrathecal Rituximab in Treating Patients With Recurrent CNS Lymphoma

Who this might be right for
Brain and Central Nervous System TumorsLymphoma
University of California, San Francisco 10
Early research (Phase 1)Not Yet RecruitingNCT07199413
What this trial is testing

Allogeneic, Antigen-Presenting, GM-CSF-secreting, SV-BR-1-GM Whole Cell-Therapeutic Vaccine and Immunotherapy: A Phase I Pilot Safety and Feasibility Study for Solid Tumor Patients With CNS Metastases

Who this might be right for
Brain MetastasesLeptomeningeal Metastasis
Medical College of Wisconsin 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT04343573
What this trial is testing

Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From Solid Tumors

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 102
Testing effectiveness (Phase 2)UnknownNCT04148898
What this trial is testing

Osimertinib With or Without Bevacizumab for EGFR- Mutant Non-small Cell Lung Cancer With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisNon-small Cell Lung CancerEGFR Activating Mutation
Second Affiliated Hospital of Nanchang University 80
Early research (Phase 1)Looking for participantsNCT06431685
What this trial is testing

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

Who this might be right for
NSCLCLow Dose RadiotherapyPD-1 Inhibitor+1 more
Sichuan University 10
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