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Results for “Cardiac Myosins”

8 trials

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Showing 8 of 8 results

Early research (Phase 1)Study completedNCT02882672
What this trial is testing

Changes in Adiponectin and Cardiovascular Disease Risk Factors in Overweight Patients

Who this might be right for
ExerciseCardiac MyosinsPatients
University of Isfahan 60
Testing effectiveness (Phase 2)Study completedNCT01786512
What this trial is testing

COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure

Who this might be right for
Modified Release Oral FormulationLeft Ventricular Systolic DysfunctionChronic Heart Failure+4 more
Cytokinetics 544
Early research (Phase 1)Study completedNCT01737866
What this trial is testing

Pharmacokinetics Study of AMG 423 in Healthy Subjects and Subjects With Various Degrees of Renal Insufficiency

Who this might be right for
Heart Failure
Cytokinetics 13
Not applicableActive Not RecruitingNCT06372457
What this trial is testing

COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Bristol-Myers Squibb 500
Testing effectiveness (Phase 2)Ended earlyNCT04572893
What this trial is testing

Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other Causalities

Who this might be right for
Primary Familial Dilated Cardiomyopathy
Bristol-Myers Squibb 41
Testing effectiveness (Phase 2)Looking for participantsNCT05836259
What this trial is testing

Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

Who this might be right for
Hypertrophic Cardiomyopathy
Tenaya Therapeutics 30
Testing effectiveness (Phase 2)Looking for participantsNCT06793371
What this trial is testing

AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

Who this might be right for
Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)
Cytokinetics 60
Post-approval studies (Phase 4)Study completedNCT01798992
What this trial is testing

Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart

Who this might be right for
Idiopathic Dilated Cardiomyopathy
University of Colorado, Denver 56