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Results for “Cardiac TTR Amyloidosis”

122 trials

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Showing 20 of 122 results

Testing effectiveness (Phase 2)Study completedNCT00694161
What this trial is testing

The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy

Who this might be right for
Cardiomyopathy
Pfizer 35
Large-scale testing (Phase 3)Active Not RecruitingNCT04136171
What this trial is testing

CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

Who this might be right for
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)
Ionis Pharmaceuticals, Inc. 1,438
Not applicableUnknownNCT05087953
What this trial is testing

Autonomic Evaluation of Patients With Hereditary Amyloidotic Cardiomyopathy: Hereditary Amyloidotic Heart Disease

Who this might be right for
Autonomic Nervous System DiseaseAmyloid Neuropathies
University of Sao Paulo General Hospital 60
Not applicableLooking for participantsNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableNot Yet RecruitingNCT07398950
What this trial is testing

Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Who this might be right for
ATTR Amyloidosis With CardiomyopathyHeart Failure
Yale University 150
Not applicableEnded earlyNCT03328338
What this trial is testing

Mitochondrial Function in Transthyretin Amyloidosis

Who this might be right for
Cardiac Amyloidosis
University Hospital Center of Martinique 12
Not applicableStudy completedNCT03842163
What this trial is testing

Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Pfizer 812
Not applicableUnknownNCT05501847
What this trial is testing

Heart Failure: Don't Forget the Role of Amyloidosis

Who this might be right for
Heart Failure
University Hospital Center of Martinique 446
Not applicableUnknownNCT04986826
What this trial is testing

Exercise Effect on Transthyretin Stability

Who this might be right for
Amyloidosis TransthyretinAthlete Heart
Oregon Health and Science University 24
Not applicableEnded earlyNCT04424914
What this trial is testing

Global Prevalence of ATTR-CM in Participants With HFpEF

Who this might be right for
Transthyretin Amyloid CardiomyopathyHeart Failure With Preserved Ejection Fraction
Pfizer 347
Testing effectiveness (Phase 2)Looking for participantsNCT06318260
What this trial is testing

Haemodynamic Effects of Dobutamine in Patients With Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt)

Who this might be right for
ATTR Amyloidosis Wild Type
Steen Hvitfeldt Poulsen 15
Large-scale testing (Phase 3)Looking for participantsNCT06563895
What this trial is testing

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+3 more
Eidos Therapeutics, a BridgeBio company 587
Not applicableLooking for participantsNCT06978660
What this trial is testing

Multicenter Study for the Validation of an AI-based ECG Platform for Early Cardiac Amyloidosis Diagnosis

Who this might be right for
Transthyretin Cardiac Amyloidosis
Idoven 1903 S.L. 2,000
Not applicableUnknownNCT05896904
What this trial is testing

Clinical Comparison of Patients With Transthyretin Cardiac Amyloidosis and Patients With Heart Failure With Reduced Ejection Fraction

Who this might be right for
Transthyretin Amyloid CardiomyopathyHeart Failure
Aarhus University Hospital Skejby 100
Not applicableLooking for participantsNCT05489549
What this trial is testing

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Who this might be right for
Amyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center 500
Early research (Phase 1)Study completedNCT05374564
What this trial is testing

Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR Cardiomyopathy

Who this might be right for
Cardiomyopathies, Primary
Yale University 12
Not applicableActive Not RecruitingNCT06073574
What this trial is testing

CARDIO-TTRansform Magnetic Resonance Imaging (MRI) Sub-study

Who this might be right for
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)
Ionis Pharmaceuticals, Inc. 150
Very early researchStudy completedNCT05023889
What this trial is testing

Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy

Who this might be right for
PolyneuropathiesWild Type ATTR AmyloidosisWild-Type Transthyretin-Related (ATTR)Amyloidosis+2 more
Austin Neuromuscular Center 10
Early research (Phase 1)Ended earlyNCT03417830
What this trial is testing

Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging

Who this might be right for
Amyloidosis
GlaxoSmithKline 2
Not applicableActive Not RecruitingNCT07062848
What this trial is testing

An Observational Study Using Artificial Intelligence (AI) Algorithms on Electrocardiography (ECG), Point-of-care Ultrasound (POCUS), and Transthoracic Echocardiophy (TTE) to Estimate the Under-diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Across a Diverse Range of US Health Systems.

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Yale University 1,500,000
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