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Results for “Cardiac TTR Amyloidosis”

129 trials

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Showing 20 of 129 results

Not applicableStudy completedNCT03842163
What this trial is testing

Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Pfizer 812
Not applicableEnded earlyNCT06338839
What this trial is testing

Transthyretin Amyloidosis Cardiomyopathy in Patients With HFpEF in Russia

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy, Heart Failure With Preserved Ejection Fraction
AstraZeneca 1,770
Post-approval studies (Phase 4)Study completedNCT05633563
What this trial is testing

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis

Who this might be right for
Transthyretin Amyloid CardiopathyMitochondrial Pathology
Steen Hvitfeldt Poulsen 24
Large-scale testing (Phase 3)Study completedNCT03860935
What this trial is testing

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+2 more
Eidos Therapeutics, a BridgeBio company 632
Not applicableStudy completedNCT06073574
What this trial is testing

CARDIO-TTRansform Magnetic Resonance Imaging (MRI) Sub-study

Who this might be right for
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)
Ionis Pharmaceuticals, Inc. 160
Not applicableUnknownNCT04563286
What this trial is testing

Patient-Reported Outcome Measures in Wild-Type and Variant Cardiac Transthyretin Amyloidosis

Who this might be right for
Transthyretin Amyloidosis
University of Messina 250
Not applicableNot Yet RecruitingNCT07591038
What this trial is testing

PET/CT Imaging in Carriers of TTR Mutations

Who this might be right for
ATTRATTR Gene MutationCardiomyopathy+1 more
University of Texas Southwestern Medical Center 80
Large-scale testing (Phase 3)Looking for participantsNCT07052903
What this trial is testing

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals 1,750
Not applicableLooking for participantsNCT06034405
What this trial is testing

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Who this might be right for
Lumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild Type+3 more
Columbia University 1,663
Not applicableEnded earlyNCT04424914
What this trial is testing

Global Prevalence of ATTR-CM in Participants With HFpEF

Who this might be right for
Transthyretin Amyloid CardiomyopathyHeart Failure With Preserved Ejection Fraction
Pfizer 347
Not applicableLooking for participantsNCT04535349
What this trial is testing

Quantitative Analysis of Myocardial Uptake of Bone Radiopharmaceuticals in Patients With Cardiac ATTR Amyloidosis

Who this might be right for
Amyloidosis Transthyretin
University Hospital, Caen 35
Not applicableStudy completedNCT06372301
What this trial is testing

Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid CardiomyopathyAortic Stenosis
Steen Hvitfeldt Poulsen 15
Large-scale testing (Phase 3)Study completedNCT03481972
What this trial is testing

Doxycycline and Tauroursodeoxycholic Acid (Doxy/TUDCA) Plus Standard Supportive Therapy Versus Standard Supportive Therapy Alone in Cardiac Amyloidosis Caused by Transthyretin

Who this might be right for
TTR Cardiac Amyloidosis
Fondazione IRCCS Policlinico San Matteo di Pavia 102
Large-scale testing (Phase 3)Enrolling By InvitationNCT06679946
What this trial is testing

Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Who this might be right for
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Alnylam Pharmaceuticals 700
Large-scale testing (Phase 3)Not Yet RecruitingNCT07116473
What this trial is testing

To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)

Who this might be right for
Amyloidosis in Transthyretin (TTR)Amyloidosis, FamilialAmyloid Cardiomyopathy+7 more
Eidos Therapeutics, a BridgeBio company 250
Not applicableUnknownNCT05087953
What this trial is testing

Autonomic Evaluation of Patients With Hereditary Amyloidotic Cardiomyopathy: Hereditary Amyloidotic Heart Disease

Who this might be right for
Autonomic Nervous System DiseaseAmyloid Neuropathies
University of Sao Paulo General Hospital 60
Post-approval studies (Phase 4)Looking for participantsNCT07306949
What this trial is testing

Real-Life Clinical Efficacy of Acoramidis in Participants With ATTR-CM and Association With Cardiac Biomarkers

Who this might be right for
Transthyretin-type Cardiac Amyloidosis
Alexion Pharmaceuticals, Inc. 200
Not applicableStudy completedNCT01705626
What this trial is testing

Screening for the Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR FAP)

Who this might be right for
Polyneuropathy, AmyloidNeuropathic PainCardiac Failure+2 more
CENTOGENE GmbH Rostock 500
Testing effectiveness (Phase 2)Active Not RecruitingNCT06260709
What this trial is testing

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

Who this might be right for
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Novo Nordisk A/S 80
Not applicableUnknownNCT04956965
What this trial is testing

High Resolution Three-dimensional Maps of the Right Chambers in Patient Diagnosed With Cardiac Amyloidosis

Who this might be right for
Cardiac AmyloidosisCardiac Disease
University Hospital Center of Martinique 24
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