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Results for “Castration-Sensitive Prostate Carcinoma”

74 trials

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Showing 20 of 74 results

Large-scale testing (Phase 3)Looking for participantsNCT07028853
What this trial is testing

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Who this might be right for
Metastatic Castration Sensitive Prostate Cancer (mCSPC)Hormone Sensitive Prostate CancerProstate Cancer+1 more
Pfizer 1,000
Large-scale testing (Phase 3)Active Not RecruitingNCT04497844
What this trial is testing

Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-MutatedProstatic Neoplasms (mCSPC)

Who this might be right for
Prostatic Neoplasms
Janssen Research & Development, LLC 696
Not applicableLooking for participantsNCT07691697
What this trial is testing

PSMA PET-Staged Comprehensive Progression-Directed Radiotherapy for Limited Progression in Prostate Cancer

Who this might be right for
Oligoprogressive Prostate CancerMetastatic Prostate Cancer
Affidea Nu-med Center of Oncological DIagnostics and Therapy 1,000
Early research (Phase 1)Looking for participantsNCT05997615
What this trial is testing

Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

Who this might be right for
Hormone-refractory Prostate Cancer
Astellas Pharma Global Development, Inc. 437
Early research (Phase 1)Active Not RecruitingNCT06229366
What this trial is testing

[Ac-225]-PSMA-62 Trial in Oligometastatic Hormone Sensitive and Metastatic Castration Resistant Prostate Cancer

Who this might be right for
Prostate CancerMetastatic Castration-resistant Prostate CancerOligometastatic Prostate Carcinoma+1 more
Eli Lilly and Company 142
Testing effectiveness (Phase 2)Active Not RecruitingNCT03361735
What this trial is testing

Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate Cancer

Who this might be right for
Prostate Adenocarcinoma
City of Hope Medical Center 25
Not applicableLooking for participantsNCT07290270
What this trial is testing

Real-world Use of Lutetium (177Lu) Vipivotide Tetraxetan in China(PSMAreal CN)

Who this might be right for
Metastatic Prostate Cancer
Novartis Pharmaceuticals 170
Testing effectiveness (Phase 2)Active Not RecruitingNCT04550494
What this trial is testing

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Castration-Resistant Prostate Carcinoma+28 more
National Cancer Institute (NCI) 29
Testing effectiveness (Phase 2)Looking for participantsNCT04633252
What this trial is testing

A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer

Who this might be right for
Cancer Of ProstateProstate Neoplasms
National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)Study completedNCT02649855
What this trial is testing

Docetaxel and PROSTVAC for Metastatic Castration-Sensitive Prostate Cancer

Who this might be right for
Prostate CancerProstate NeoplasmsNeoplasms, Prostatic
National Cancer Institute (NCI) 74
Early research (Phase 1)Looking for participantsNCT04729114
What this trial is testing

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

Who this might be right for
Prostate CancerMetastatic Castration Resistant Prostate CancerMetastatic Castration-sensitive Prostate Cancer
Astellas Pharma Global Development, Inc. 174
Early research (Phase 1)Looking for participantsNCT07339267
What this trial is testing

Evaluate the Safety and Drug Levels of ASP5541 in Chinese Participants With Prostate Cancer

Who this might be right for
Prostate CancerMetastatic Castration-Resistant Prostate CancerMetastatic Hormone Sensitive Prostate Cancer
Astellas Pharma Global Development, Inc. 12
Testing effectiveness (Phase 2)WithdrawnNCT02065323
What this trial is testing

Dovitinib With Androgen Deprivation Therapy (ADT) in Patients With Metastatic Prostate Cancer Receiving Primary ADT

Who this might be right for
Prostate Cancer
Oscar Goodman, Jr.
Large-scale testing (Phase 3)Looking for participantsNCT07723248
What this trial is testing

Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1)

Who this might be right for
Metastatic Castration Resistant Prostate Cancer
ORIC Pharmaceuticals 600
Not applicableStudy completedNCT05149131
What this trial is testing

A Study Called AWARENESS Using Data From Men in Alberta to Observe Treatment Patterns for Metastatic Castration-sensitive Prostate Cancer

Who this might be right for
Metastatic Castration-sensitive Prostate Cancer
Bayer 960
Post-approval studies (Phase 4)UnknownNCT04601441
What this trial is testing

Study to Evaluate ctDNA of mCSPC Patients Receiving Apalutamide in Japan

Who this might be right for
Metastatic Castration-sensitive Prostate Cancer
Kindai University 100
Not applicableLooking for participantsNCT06334120
What this trial is testing

An Observational Study to Learn More About the Safety of Darolutamide in Men With Prostate Cancer in Korea

Who this might be right for
Non-metastatic Castration-resistant Prostate CancerMetastatic Hormone-sensitive Prostate Cancer
Bayer 600
Testing effectiveness (Phase 2)Study completedNCT01875250
What this trial is testing

Enzalutamide in Combination With PSA-TRICOM in Patients With Non-Metastatic Castration Sensitive Prostate Cancer

Who this might be right for
Prostate Cancer
National Cancer Institute (NCI) 38
Early research (Phase 1)Ended earlyNCT05733351
What this trial is testing

Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate Cancer

Who this might be right for
Castration-Sensitive Prostate CarcinomaMetastatic Prostate AdenocarcinomaStage IVB Prostate Cancer AJCC v8
Emory University 4
Testing effectiveness (Phase 2)Active Not RecruitingNCT04267887
What this trial is testing

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Who this might be right for
Castration-Sensitive Prostate CarcinomaMetastatic Prostate CarcinomaStage IVB Prostate Cancer AJCC v8
OHSU Knight Cancer Institute 7
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