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Results for “Cell Hypoxia”

178 trials

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Showing 20 of 178 results

Early research (Phase 1)Study completedNCT01149915
What this trial is testing

Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+3 more
Threshold Pharmaceuticals 40
Large-scale testing (Phase 3)Active Not RecruitingNCT04736706
What this trial is testing

Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 1,854
Not applicableUnknownNCT06007989
What this trial is testing

Assessing the Relationship Between Hypoxia and the Immune Environment in Myeloma Patients (CHIME)

Who this might be right for
Myeloma
The Christie NHS Foundation Trust 10
Not applicableEnded earlyNCT01617980
What this trial is testing

Multimodal Hypoxia Imaging and Intensity Modulated Radiotherapy for Inoperable Non-small-cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
German Cancer Research Center 4
Very early researchLooking for participantsNCT05632562
What this trial is testing

Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma

Who this might be right for
High Grade Glioma
University of Alabama at Birmingham 20
Early research (Phase 1)Ended earlyNCT00826930
What this trial is testing

Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma

Who this might be right for
High Grade Glioma
Diffusion Pharmaceuticals Inc 1
Testing effectiveness (Phase 2)Study completedNCT02802969
What this trial is testing

Improvement of Local Control in Skull Base, Spine and Sacral Chordomas Treated by Surgery and Protontherapy Targeting Hypoxic Cells Revealed by [18F]FAZA) PET/CT Tracers

Who this might be right for
Skull Base ChordomaVertebral Chordoma
Institut Curie 64
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07299123
What this trial is testing

Phase I Clinical Study of Haplo-HSCT Combined With Hypoxic 3D-Cultured Umbilical Cord MSC for the Treatment of SAA

Who this might be right for
Severe Aplastic Anemia (SAA)Severe Aplastic Anemia, RefractorySevere Aplastic Anemia
Chinese PLA General Hospital 40
Large-scale testing (Phase 3)Not Yet RecruitingNCT06477939
What this trial is testing

Study of Adding or Not Liposomal Transcrocetin (L-TC) With Concomitant HypoFractionated Radiation ThErapy and TEmozolomide in Newly Diagnosed GLioblastoma (GBM) Patients

Who this might be right for
Glioblastoma
Institut de cancérologie Strasbourg Europe 554
Testing effectiveness (Phase 2)Looking for participantsNCT07049926
What this trial is testing

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

Who this might be right for
Renal Cell Carcinoma
Merck Sharp & Dohme LLC 140
Large-scale testing (Phase 3)UnknownNCT01880359
What this trial is testing

AF CRT +/- Nimorazole in HNSCC

Who this might be right for
Locally Advanced Head and Neck HPV Negative Squamous Cell Cancers
European Organisation for Research and Treatment of Cancer - EORTC 640
Not applicableAvailableNCT07748299
What this trial is testing

NuvOx Expanded Access

Who this might be right for
GlioblastomaRespiratory Distress SyndromIschemic Stroke+1 more
NuvOx LLC
Testing effectiveness (Phase 2)Study completedNCT00107445
What this trial is testing

EF5 in Finding Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Cervical, Endometrial, or Ovarian Epithelial Cancer

Who this might be right for
Primary Peritoneal Cavity CancerStage I Endometrial CarcinomaStage I Ovarian Epithelial Cancer+13 more
National Cancer Institute (NCI) 60
Early research (Phase 1)Study completedNCT02266394
What this trial is testing

Hypoxia and Inflammatory Injury in Human Renovascular Hypertension

Who this might be right for
Renal Artery StenosisIschemic NephropathyRenovascular Disease+1 more
Mayo Clinic 42
Not applicableStudy completedNCT04409314
What this trial is testing

Hypoxia-Specific Imaging to Predict Outcomes of Chimeric Antigen Receptor T-cell Therapy

Who this might be right for
Recurrent Aggressive Non-Hodgkin LymphomaRecurrent Diffuse Large B-Cell LymphomaRecurrent High Grade B-Cell Lymphoma+9 more
University of California, San Francisco 23
Not applicableUnknownNCT04106401
What this trial is testing

Intravascular Volumes in Hypoxia During Antarctic Confinement

Who this might be right for
HypoxiaConfinement
Ecole Nationale des Sports de Montagne 24
Not applicableEnded earlyNCT00896961
What this trial is testing

EF5 to Evaluate Tumor Hypoxia in Patients With High-Grade Soft Tissue Sarcoma or Mouth Cancer

Who this might be right for
Stage I Adult Soft Tissue SarcomaStage I Squamous Cell Carcinoma of the Lip and Oral CavityStage II Adult Soft Tissue Sarcoma+3 more
National Cancer Institute (NCI) 120
Testing effectiveness (Phase 2)Study completedNCT00041028
What this trial is testing

EF5 in Assessing Tumor Response to Anticancer Therapy in Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
Duke University 60
Early research (Phase 1)Ended earlyNCT03526588
What this trial is testing

Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH)

Who this might be right for
Congenital Diaphragmatic Hernia
The University of Texas Health Science Center, Houston 3
Early research (Phase 1)UnknownNCT01962233
What this trial is testing

Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Hypoxic Ischemic Encephalopathy

Who this might be right for
Hypoxic Ischemic Encephalopathy
Hebei Medical University 10
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