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Results for “Cellular Apoptosis”

387 trials

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Showing 20 of 387 results

Testing effectiveness (Phase 2)Study completedNCT03562871
What this trial is testing

IO102 With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment of Metastatic NSCLC

Who this might be right for
NSCLC
IO Biotech 109
Testing effectiveness (Phase 2)Study completedNCT02860546
What this trial is testing

A Study Evaluating TAS-102 Plus Nivolumab in Patients With MSS CRC

Who this might be right for
Refractory Metastatic Colorectal Cancer
Taiho Oncology, Inc. 18
Early research (Phase 1)Looking for participantsNCT07481175
What this trial is testing

Inhibiting the Anti-apoptotic Factor, BCL-2, at the Time of ART Initiation to Promote Apoptosis of HIV-infected Cells and Restrict the Seeding of the HIV Reservoir (The INITIATE Study)

Who this might be right for
HIV-1
Thomas Aagaard Rasmussen 38
Testing effectiveness (Phase 2)Active Not RecruitingNCT06483334
What this trial is testing

Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04)

Who this might be right for
Metastatic Urothelial CarcinomaLocally Advanced Urothelial Carcinoma
Merck Sharp & Dohme LLC 38
Large-scale testing (Phase 3)Active Not RecruitingNCT03553836
What this trial is testing

Safety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 976
Testing effectiveness (Phase 2)Temporarily pausedNCT03779100
What this trial is testing

Lenvatinib Plus PD-1 Antibody for Unresectable ICC

Who this might be right for
Intrahepatic Cholangiocarcinoma
Shi Ming 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT06305767
What this trial is testing

A Clinical Study of Intismeran Autogene (V940) Treatment and Pembrolizumab in People With Bladder Cancer (V940-005/INTerpath-005)

Who this might be right for
Bladder Cancer
Merck Sharp & Dohme LLC 230
Large-scale testing (Phase 3)Study completedNCT03834506
What this trial is testing

Study of Pembrolizumab (MK-3475) Plus Docetaxel Versus Placebo Plus Docetaxel in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-921/KEYNOTE-921)

Who this might be right for
Prostatic Neoplasms
Merck Sharp & Dohme LLC 1,030
Large-scale testing (Phase 3)Study completedNCT03066778
What this trial is testing

Pembrolizumab (MK-3475) in Combination With Etoposide/Platinum (Cisplatin or Carboplatin) for Participants With Extensive Stage Small Cell Lung Cancer (MK-3475-604/KEYNOTE-604)

Who this might be right for
Small Cell Lung Cancer (SCLC)
Merck Sharp & Dohme LLC 453
Large-scale testing (Phase 3)Study completedNCT00432913
What this trial is testing

Effect of 2 Doses of EPA on Apoptosis and Cell Proliferation on Colon Mucosa

Who this might be right for
Adenomatous Polyps
S.L.A. Pharma AG 120
Not applicableStudy completedNCT05417061
What this trial is testing

Serum and Saliva Sirtuin 6, Lipoxin A4, Caspase8 Levels in Correlation With Periodontal Status in Severe Periodontitis

Who this might be right for
PeriodontitisDiagnose Disease
Istanbul Medipol University Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT06041503
What this trial is testing

Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)

Who this might be right for
Adenocarcinoma of the BladderSquamous Cell Carcinoma of the BladderTesticular Germ Cell Tumors
National Cancer Institute (NCI) 68
Testing effectiveness (Phase 2)Study completedNCT02039674
What this trial is testing

Pembrolizumab (MK-3475) in Combination With Chemotherapy or Immunotherapy in Participants With Non-small Cell Lung Cancer (MK-3475-021/KEYNOTE-021)

Who this might be right for
Non-small Cell Lung Carcinoma
Merck Sharp & Dohme LLC 267
Very early researchActive Not RecruitingNCT04134325
What this trial is testing

Study of PD-1 Inhibitors After CD30.CAR T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma

Who this might be right for
Relapsed Hodgkin LymphomaRefractory Hodgkin Lymphoma
UNC Lineberger Comprehensive Cancer Center 10
Testing effectiveness (Phase 2)Looking for participantsNCT06780085
What this trial is testing

Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC 96
Large-scale testing (Phase 3)Ended earlyNCT04428333
What this trial is testing

Study of GSK3359609 With Pembrolizumab and 5-fluorouracil (5-FU)-Platinum Chemotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Neoplasms, Head and Neck
GlaxoSmithKline 117
Testing effectiveness (Phase 2)UnknownNCT02828878
What this trial is testing

Prevention of Acute Graft Versus Host Disease in Patients Undergoing Allogeneic ApoGraft Stem Cell Transplantation

Who this might be right for
Hematological Malignancies
Cellect Biotechnology 12
Testing effectiveness (Phase 2)Study completedNCT02879617
What this trial is testing

A Clinical Trial of Durvalumab (MEDI4736) as 1st Line Therapy in Advanced Non-small Cell Lung Cancer Patients

Who this might be right for
Non-Small Cell Lung Cancer NSCLC
Academic Thoracic Oncology Medical Investigators Consortium 47
Large-scale testing (Phase 3)Study completedNCT04774380
What this trial is testing

Study of Durvalumab in Combination With Platinum and Etoposide for the First Line Treatment of Patients With Extensive-stage Small Cell Lung Cancer

Who this might be right for
Extensive-stage Small Cell Lung Cancer
AstraZeneca 152
Testing effectiveness (Phase 2)Active Not RecruitingNCT04626479
What this trial is testing

Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 400
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